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上海药物研究所 [64]
武汉病毒研究所 [2]
复旦大学上海医学院 [1]
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期刊论文 [60]
学位论文 [4]
会议论文 [3]
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2017 [1]
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Psychiatry [1]
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Activation of D1R/PKA/mTOR signaling cascade in medial prefrontal cortex underlying the antidepressant effects of l-SPD
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Zhang, Bing
;
Guo, Fei
;
Ma, Yuqin
;
Song, Yingcai
;
Lin, Rong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Design, synthesis and evaluation of benzo[a]thieno[3,2-g]quinolizines as novel l-SPD derivatives possessing dopamine D-1, D-2 and serotonin 5-HT1A multiple action profiles
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 21, 页码: 5838-5846
作者:
Li, Zeng
;
Huang, Jiye
;
Sun, Haifeng
;
Zhou, Shengbin
;
Guo, Lin
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
l-SPD
Tetrahydroprotoberberine
Dopamine receptor
Serotonin receptor
Multiple action
L-Stepholidine, a natural dopamine receptor D1 agonist and D2 antagonist, inhibits heroin-induced reinstatement
期刊论文
NEUROSCIENCE LETTERS, 2014, 卷号: 559, 页码: 67-71
作者:
Ma, Baomiao
;
Yue, Kai
;
Chen, Lin
;
Tian, Xiang
;
Ru, Qin
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/01/08
L-Stepholidine
Heroin
Dopamine receptor
Self-administration
Relapse
L-Stepholidine, a naturally occurring dopamine D1 receptor agonist and D2 receptor antagonist, attenuates heroin self-administration and cue-induced reinstatement in rats
期刊论文
NEUROREPORT, 2014, 卷号: 25, 期号: 1, 页码: 7-11
作者:
Yue, Kai
;
Ma, Baomiao
;
Chen, Lin
;
Tian, Xiang
;
Ru, Qin
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2019/01/08
dopamine receptor
heroin
l-stepholidine
relapse
self-administration
L-stepholidine blocks methamphetamine-induced locomotor sensitization in mice
会议论文
作者:
Ma, Bao Miao
;
Yue, Kai
;
Xing, Jun Qiao
;
Gong, Xiao Kang
;
Ru, Qin
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/01/08
L-stepholidine, a naturally occurring dopamine D1 receptor agonist and D2 receptor antagonist, attenuates methamphetamine self-administration in rats
会议论文
作者:
Yue, Kai
;
Ma, Bao Miao
;
Xing, Jun Qiao
;
Gong, Xiao Kang
;
Ru, Qin
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2019/01/08
Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D-1, D-2 and serotonin 5-HT1A multi-action profile
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 4, 页码: 856-868
作者:
Sun, Haifeng
;
Zhu, Liyuan
;
Yang, Huicui
;
Qian, Wangke
;
Guo, Lin
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Asymmetric synthesis
Tetrahydroprotoberberines
Dopamine receptors
Serotonin receptors
Multi-action
New pharmacological profile
Design, synthesis, and pharmacological evaluation of novel tetrahydroprotoberberine derivatives: Selective inhibitors of dopamine D-1 receptor
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2012, 卷号: 20, 期号: 15, 页码: 4862-4871
作者:
Qian, Wangke
;
Lu, Weijian
;
Sun, Haifeng
;
Li, Zeng
;
Zhu, Liyuan
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Tetrahydroprotoberberine
Dopamine receptor
Anti-substance abuse
Antagonist
Molecular Insights into the D1R Agonist and D2R/D3R Antagonist Effects of the Natural Product (-)-Stepholidine: Molecular Modeling and Dynamics Simulations
期刊论文
JOURNAL OF PHYSICAL CHEMISTRY B, 2012, 卷号: 116, 期号: 28, 页码: 8121-8130
作者:
Li, Bian
;
Li, Wei
;
Du, Peng
;
Yu, Kun Qian
;
Fu, Wei
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Dopamine D-1 receptor and serotonin 5-HT1A receptor agonist effects of the natural product (-)-stepholidine: molecular modelling and dynamics simulations
期刊论文
MOLECULAR SIMULATION, 2012, 卷号: 38, 期号: 12
作者:
Gong, Yunguo
;
Fu, Wei
;
Chen, Kaixian
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
molecular dynamics
l-SPD (l-stepholidine)
G-protein-coupled receptor (GPCR)
D-1 receptor
5-HT1A receptor
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