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Notch pathway inhibition using DAPT, a gamma-secretase inhibitor (GSI), enhances the antitumor effect of cisplatin in resistant osteosarcoma 期刊论文
MOLECULAR CARCINOGENESIS, 2019, 卷号: 58, 期号: 1
作者:  Dai, Guo;  Deng, Shuang;  Guo, Weichun;  Yu, Ling;  Yang, Jian
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/05
Alzheimer's disease hypothesis and related therapies 期刊论文
TRANSLATIONAL NEURODEGENERATION, 2018, 卷号: 7
作者:  Du, Xiaoguang;  Wang, Xinyi;  Geng, Meiyu
收藏  |  浏览/下载:22/0  |  提交时间:2019/01/08
IL6 blockade potentiates the anti-tumor effects of gamma-secretase inhibitors in Notch3-expressing breast cancer 期刊论文
CELL DEATH AND DIFFERENTIATION, 2018, 卷号: 25, 期号: 2
作者:  Wang, Dong;  Xu, Jiahui;  Liu, Bingjie;  He, Xueyan;  Zhou, Lei
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/05
Visualization of Alzheimer's Disease Related alpha-/beta-/gamma-Secretase Ternary Complex by Bimolecular Fluorescence Complementation Based Fluorescence Resonance Energy Transfer 期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11, 期号: 1, 页码: 431
作者:  Wang, Xin;  Pei, Gang
收藏  |  浏览/下载:25/0  |  提交时间:2019/04/28
Gamma secretase dependent release of the CD44 cytoplasmic tail upregulates IFIl 6 in cd44 tumor cells, MEFs and macrophages 期刊论文
PLOS ONE, 2018, 卷号: Vol.13 No.12
作者:  Herrlich, Peter;  Ruschel, Anne;  Gereke, Marcus;  Minnich, Kerstin;  Li, Yong
收藏  |  浏览/下载:8/0  |  提交时间:2019/04/24
Cervical Cancer Cell Growth, Drug Resistance, and Epithelial-Mesenchymal Transition Are Suppressed by gamma-Secretase Inhibitor RO4929097 期刊论文
MEDICAL SCIENCE MONITOR, 2018, 卷号: 24
作者:  Wang, Lu;  Dai, Guo;  Yang, Jian;  Wu, Wanrong;  Zhang, Wei
收藏  |  浏览/下载:8/0  |  提交时间:2019/12/05
gamma-Secretase inhibitor reduces immunosuppressive cells and enhances tumour immunity in head and neck squamous cell carcinoma 期刊论文
INTERNATIONAL JOURNAL OF CANCER, 2018, 卷号: 142, 期号: 5
作者:  Mao, Liang;  Zhao, Zhi-Li;  Yu, Guang-Tao;  Wu, Lei;  Deng, Wei-Wei
收藏  |  浏览/下载:13/0  |  提交时间:2019/12/05
Defining the minimum substrate and charge recognition model of gamma-secretase 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 10, 页码: 1412-1424
作者:  Yan, Yan;  Xu, Ting-Hai;  Melcher, Karsten;  Xu, H. Eric
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Dimerization of the transmembrane domain of amyloid precursor protein is determined by residues around the gamma - secretase cleavage sites 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 期号: 38, 页码: 15826-15837
作者:  Yan, Yan;  Xu, Ting-Hai;  Harikumar, Kaleeckal G.;  Miller, Laurence J.;  Melcher, Karsten
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Research advances in the treatment of Alzheimer's disease with polysaccharides from traditional Chinese medicine 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2017, 卷号: 15, 期号: 9, 页码: 641-652
作者:  Liu Qin;  Wang Shun-Chun;  Ding Kan
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08


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