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Stabilizing photo-sensitive colchicine through rebalancing electron distribution of the reactive tropolone ring 期刊论文
CRYSTENGCOMM, 2021, 卷号: 23, 期号: 1, 页码: 30-34
作者:  Ma, Xiaoyu;  Zhu, Bingqing;  Yang, Zeen;  Jiang, Yuhang;  Mei, Xuefeng
收藏  |  浏览/下载:9/0  |  提交时间:2021/05/24
Therapeutic drugs for SARS-CoV-2 treatment: Current state and perspective 期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2021, 卷号: 90, 页码: 19
作者:  Bolarin, Joshua Adedeji;  Oluwatoyosi, Mercy Adaramodu;  Orege, Joshua Iseoluwa;  Ayeni, Emmanuel Ayodeji;  Ibrahim, Yusuf Ajibola
收藏  |  浏览/下载:34/0  |  提交时间:2021/03/29
Gene body demethylation increases expression and is associated with self-pruning during grape genome duplication 期刊论文
HORTICULTURE RESEARCH, 2020, 卷号: 7, 期号: 1
作者:  Zou, Luming;  Liu, Wenwen;  Zhang, Zhan;  Edwards, Everard J.;  Gathunga, Elias Kirabi
收藏  |  浏览/下载:28/0  |  提交时间:2022/03/01
1-Phenyl-dihydrobenzoindazoles as novel colchicine site inhibitors: Structural basis and antitumor efficacy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 448-456
作者:  Jiang, Junhang;  Zhang, Hao;  Wang, Chongqing;  Zhang, Qingsen;  Fang, Shaoyu
收藏  |  浏览/下载:16/0  |  提交时间:2020/07/01
Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 7, 页码: 10
作者:  Zhang, Yu;  Goto, Masuo;  Oda, Akifumi;  Hsu, Pei-Ling;  Guo, Ling-Li
收藏  |  浏览/下载:67/0  |  提交时间:2019/07/29
3,5-Diaryl-1H-pyrazolo[3,4-b]pyridines as potent tubulin polymerization inhibitors: Rational design, synthesis and biological evaluation 期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: Vol.168, 页码: 426-435
作者:  Min'an Zhai;  Shiyuan Liu;  Meiqi Gao;  Long Wang;  Jun Sun
收藏  |  浏览/下载:30/0  |  提交时间:2019/12/13
Synthesis and bioevaluation of diarylpyrazoles as antiproliferative agents 期刊论文
European Journal of Medicinal Chemistry, 2019
作者:  Chao Wang;  Shuang Yang;  Jianan Du;  Jia Ni;  Yue Wu
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/13
Discover 4 beta-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 170, 页码: 73-86
作者:  Zhao, Wei;  He, Long;  Xiang, Tian-Le;  Tang, Ya-Jie
收藏  |  浏览/下载:6/0  |  提交时间:2019/12/11
Tubulin colchicine site binding agent LL01 displays potent antitumor efficiency both in vitro and in vivo with suitable drug-like properties 期刊论文
Investigational New Drugs, 2019
作者:  Wu J.-D.;  Cui Y.-J.;  Zhou Y.-G.;  Tang L.-Q.;  Zhang C.-M.
收藏  |  浏览/下载:11/0  |  提交时间:2019/12/11
Identification of novel and potent small-molecule inhibitors of tubulin with antitumor activities by virtual screening and biological evaluations 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 7, 页码: 659-664
作者:  Liu, Guangpu;  Jiao, Yang;  Huang, Chunxi;  Chang, Ping
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/11


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