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Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:  Bao, Weilian;  Liu, Xiaohong;  You, Yan;  Hou, Hui;  Wang, Xu
收藏  |  浏览/下载:57/0  |  提交时间:2021/11/16
Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 12, 页码: 8194-8207
作者:  Du, Daohai;  Xu, Dandan;  Zhu, Licheng;  Stazi, Giulia;  Zwergel, Clemens
收藏  |  浏览/下载:73/0  |  提交时间:2021/08/17
Identification and Assessments of Novel and Potent Small-Molecule Inhibitors of EED-EZH2 Interaction of Polycomb Repressive Complex 2 by Computational Methods and Biological Evaluations 期刊论文
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 1, 页码: 58-63
作者:  Zhu, Kongkai;  Du, Daohai;  Yang, Rui;  Tao, Hongrui;  Zhang, Hua
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/01
The Development of Inhibitors Targeting the Mixed Lineage Leukemia 1 (MLL1)-WD Repeat Domain 5 Protein (WDR5) Protein-Protein Interaction 期刊论文
CURRENT MEDICINAL CHEMISTRY, 2020, 卷号: 27, 期号: 33, 页码: 5530-5542
作者:  Ye, Xiaoqing;  Chen, Gang;  Jin, Jia;  Zhang, Binzhong;  Wang, Yinda
收藏  |  浏览/下载:14/0  |  提交时间:2020/12/24
Development of Small-Molecules Targeting Receptor Activator of Nuclear Factor-kappa B Ligand (RANKL)-Receptor Activator of Nuclear Factor-kappa B (RANK) Protein-Protein Interaction by Structure-Based Virtual Screening and Hit Optimization 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5370-5381
作者:  Jiang, Min;  Peng, Lei;  Yang, Kai;  Wang, Tianqi;  Yan, Xueming
收藏  |  浏览/下载:17/0  |  提交时间:2020/07/01
Tranylcypromine and 6-trifluoroethyl thienopyrimidine hybrid as LSD1 inhibitor 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 6, 页码: 844-847
作者:  Wang, Xiaowen;  Su, Mingbo;  Li, You;  Liu, Tongchao;  Wang, Yujie
收藏  |  浏览/下载:11/0  |  提交时间:2020/07/01
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal -actinin-4 expression and stabilizing integrin-cytoskeleton linkage 期刊论文
ARTHRITIS RESEARCH & THERAPY, 2019, 卷号: 21, 页码: 16
作者:  He, Shijun;  Liu, Xing;  Lin, Zemin;  Liu, Yuting;  Gu, Lei
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/01
Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage 期刊论文
Arthritis Research & Therapy, 2019, 卷号: 21, 期号: 1
作者:  He,Shijun;  Liu,Xing;  Lin,Zemin;  Liu,Yuting;  Gu,Lei
收藏  |  浏览/下载:57/0  |  提交时间:2020/07/01
Review: A Japanese population-based meta-analysis of vonoprazan versus PPI for Helicobacter pylori eradication therapy: Is superiority an illusion? 期刊论文
HELICOBACTER, 2017, 卷号: 22, 期号: 6
作者:  Dong, Shou Quan;  Singh, Tikka Prabhjot;  Wei, Xin;  Yao, Huang;  Wang, Hong Ling
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/05
'Light up' protein-protein interaction through bioorthogonal incorporation of a turn-on fluorescent probe into beta-lactamase 期刊论文
MOLECULAR BIOSYSTEMS, 2016, 卷号: 12, 期号: 12, 页码: 3544-3549
作者:  Hu, Rui;  Yap, Hong-Kin;  Fung, Yik-Hong;  Wang, Yong;  Cheong, Wing-Lam
收藏  |  浏览/下载:20/0  |  提交时间:2017/01/17


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