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A unique intra-molecular fidelity-modulating mechanism identified in a viral rna-dependent rna polymerase 期刊论文
Nucleic acids research, 2018, 卷号: 46, 期号: 20, 页码: 10840-10854
作者:  Liu, Weichi;  Shi, Xiaoling;  Gong, Peng
收藏  |  浏览/下载:45/0  |  提交时间:2019/05/08
Identification and Analysis of Novel Inhibitors against NS3 Helicase and NS5B RNA-Dependent RNA Polymerase from Hepatitis C Virus 1b (Con1) 期刊论文
FRONTIERS IN MICROBIOLOGY, 2017, 卷号: 8
作者:  Yang, Na;  Sun, Chaomin;  Zhang, Lixin;  Liu, Jianguo;  Song, Fuhang
收藏  |  浏览/下载:31/0  |  提交时间:2018/01/11
Computational study on the binding and unbinding mechanism of HCV NS5B with the inhibitor GS-461203 and substrate using conventional and steered molecular dynamics simulations 期刊论文
CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS, 2016, 卷号: 156, 页码: 72-80
作者:  Pan, DB;  Niu, YZ;  Ning, LL;  Zhang, Y;  Liu, HX
收藏  |  浏览/下载:5/0  |  提交时间:2017/01/12
Structure-based optimization and derivatization of 2-substituted quinolone-based non-nucleoside HCV NS5B inhibitors with submicromolar cellular replicon potency 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 12, 页码: 2900-2906
作者:  Cheng, Yu;  Shen, Jian;  Peng, Run-Ze;  Wang, Gui-Feng;  Zuo, Jian-Ping
收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08
Computational study on the drug resistance mechanism of hepatitis C virus NS5B RNA-dependent RNA polymerase mutants to BMS-791325 by molecular dynamics simulation and binding free energy calculations 会议论文
15th Conference on Chemometrics in Analytical Chemistry, Changsha, PEOPLES R CHINA, JUN 22-26, 2015
作者:  Pan, DB;  Niu, YZ;  Xue, WW;  Bai, QF;  Liu, HX
收藏  |  浏览/下载:3/0  |  提交时间:2017/01/20
Nucleoside Inhibitors of Hepatitis C Virus NS5B Polymerase: A Systematic Review 期刊论文
CURRENT DRUG TARGETS, 2016, 卷号: 17, 期号: 13, 页码: 1560-1576
作者:  Xie, Yuanchao;  Ogah, Comfort Alicha;  Jiang, Xiangrui;  Li, Jianfeng;  Shen, Jingshan
收藏  |  浏览/下载:13/0  |  提交时间:2019/01/08
Recent advances on the synthesis of hepatitis C virus NS5B RNA-dependent RNA-polymerase inhibitors 期刊论文
European Journal of Medicinal Chemistry: Chimie Therapeutique, 2015, 页码: 188-214
作者:  Zhao, Can;  Wang, Yinhu;  Ma, Shutao
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/17
Recent advances on the synthesis of hepatitis C virus NS5B RNA-dependent RNA-polymerase inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 102, 页码: 188-214
作者:  Zhao, Can;  Wang, Yinhu;  Ma, Shutao
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/17
Discovery of flavonoid derivatives as anti-HCV agents via pharmacophore search combining molecular docking strategy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 52, 页码: 33-43
作者:  Liu, Ming-Ming;  Zhou, Lu;  He, Pei-Lan;  Zhang, Yi-Nan;  Zhou, Jia-Yi
收藏  |  浏览/下载:17/0  |  提交时间:2019/01/08
Insight into the Structural Requirements of Benzothiadiazine Scaffold-Based Derivatives as Hepatitis C Virus NS5B Polymerase Inhibitors Using 3D-QSAR, Molecular Docking and Molecular Dynamics 期刊论文
current medicinal chemistry, 2011, 卷号: 18, 期号: 26, 页码: 4019-4028
作者:  Zhang, H-X.;  Li, Y.;  Wang, X.;  Xiao, Z-T.;  Wang, Y-H.
收藏  |  浏览/下载:20/0  |  提交时间:2015/11/12


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