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科研机构
上海药物研究所 [24]
内容类型
期刊论文 [24]
发表日期
2016 [24]
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发表日期:2016
专题:上海药物研究所
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Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis
期刊论文
CELL RESEARCH, 2016, 卷号: 26, 期号: 12, 页码: 1330-1344
作者:
Zhang, Lin
;
Xiao, Jianfeng
;
Xu, Jianrong
;
Fu, Tianran
;
Cao, Zhiwei
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
fatty acid biosynthesis
dehydratase
ACP
complex structure
Structural basis for DNA recognition by STAT6
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 卷号: 113, 期号: 46, 页码: 13015-13020
作者:
Li, Jing
;
Rodriguez, Jose Pindado
;
Niu, Fengfeng
;
Pu, Mengchen
;
Wang, Jinan
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
STAT6
N4 site DNA recognition
JAK-STAT pathway
antiviral
innate immunity
crystal structure
Three dimensional structural insight of laser drilled orifices in osmotic pump tablets
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2016, 卷号: 93, 页码: 287-294
作者:
Wu, Li
;
Wang, Lebing
;
Wang, Shuxia
;
Xiao, Tiqiao
;
Chen, Min
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Structure
Osmotic pump tablet
Synchrotron radiation X-ray microcomputed
tomography
Laser drilling
Photoswitchable arene ruthenium and pentamethylcyclopentadienyl rhodium complexes containing o-sulfonamide azobenzene ligands: Synthesis, characterization and cytotoxicity
期刊论文
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2016, 卷号: 820, 页码: 111-119
作者:
Deo, Claire
;
Wang, Huan
;
Bogliotti, Nicolas
;
Zang, Yi
;
Retailleau, Pascal
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/01/08
Azobenzene
Cytotoxicity
Rhodium
Ruthenium
Photoisomerization
X-ray structure
Synthesis and cytotoxicity evaluation of 4 '-amino-4 '-dehydroxyloleandrin derivatives
期刊论文
FITOTERAPIA, 2016, 卷号: 113, 页码: 85-90
作者:
Chen, Hu
;
Lei, Min
;
Ma, Biao
;
Liu, Miao
;
Guo, Dean
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2019/01/08
Oleandrin
Antitumor agent
Natural product
Cytotoxicity
Structure-activity relationships (SARs)
The structural basis of the dominant negative phenotype of the G alpha(i1)beta(1)gamma(2) G203A/A326S heterotrimer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 9, 页码: 1259-1272
作者:
Liu, Ping
;
Jia, Ming-zhu
;
Zhou, X. Edward
;
De Waal, Parker W.
;
Dickson, Bradley M.
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/01/08
dominant negative
G alpha(i1)beta(1)gamma(2) heterotrimer
G203A
A326S
crystal structure
GPCR
GDP
Synthesis, structure and cytotoxic activity of diethyltin N-[(2-oxyphenyl)methylene]phenylalaninates
期刊论文
APPLIED ORGANOMETALLIC CHEMISTRY, 2016, 卷号: 30, 期号: 8, 页码: 630-637
作者:
Liu, Qingtao
;
Zhang, Hao
;
Zheng, Xiaoliang
;
Wang, Wenqiang
;
Tian, Laijin
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/24
organotin complex
phenylalanine
cytotoxic activity
crystal structure
Synthesis and decreasing A beta content evaluation of arctigenin-4-yl carbamate derivatives
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 13, 页码: 2988-2991
作者:
Xu, Xingyu
;
Li, Cong
;
Lei, Min
;
Zhu, Zhiyuan
;
Yan, Jianming
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/01/08
Arctigenin (ATG)
Natural product
Arctigenin-4-yl 3-carbamate
Structure-activity relationships (SARs)
Alzheimer's disease (AD)
A fucoidan from Nemacystus decipiens disrupts angiogenesis through targeting bone morphogenetic protein 4
期刊论文
CARBOHYDRATE POLYMERS, 2016, 卷号: 144, 页码: 305-314
作者:
Wang, Wucheng
;
Chen, Huanjun
;
Zhang, Lei
;
Qin, Yi
;
Cong, Qifei
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Nemacystus decipiens
Fucoidan
Structure
Anti-angiogenic activity
Bone morphogenetic protein 4
Discovery, synthesis, and structure-activity relationships of 20S-dammar-24-en-2 alpha,3 beta,12 beta,20-tetrol (GP) derivatives as a new class of AMPK alpha 2 beta 1 gamma 1 activators
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 12, 页码: 2688-2696
作者:
Dong, Chenhuan
;
Xie, Zhifu
;
Yu, Yanyan
;
Li, Jia
;
Liu, Junhua
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Gynostemma yixingense
Dammarane-type
AMPK
AMPK heterotrimer alpha 2 beta 1 gamma 1
Activators
Structure-activity relationships
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