CORC

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CORC

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Structures of human mGlu2 and mGlu7 homo- and heterodimers 期刊论文
NATURE, 2021, 卷号: 594, 期号: 7864, 页码: 589-+
作者:  Du, Juan;  Wang, Dejian;  Fan, Hongcheng;  Xu, Chanjuan;  Tai, Linhua
收藏  |  浏览/下载：26/0  |  提交时间：2021/08/17
Design and synthesis of selective degraders of EGFR(L858R/T790M) mutant 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 192, 页码: 14
作者:  Zhang, Xin;  Xu, Fang;  Tong, Linjiang;  Zhang, Tao;  Xie, Hua
收藏  |  浏览/下载：80/0  |  提交时间：2020/07/01
YL143, a novel mutant selective irreversible EGFR inhibitor, overcomes EGFR(L858R, T790M)-mutant resistance in vitro and in vivo 期刊论文
CANCER MEDICINE, 2018, 卷号: 7, 期号: 4, 页码: 1430-1439
作者:  Zhang, Zhang;  Zou, Jian;  Yu, Lei;  Luo, Jinfeng;  Li, Yan
收藏  |  浏览/下载：70/0  |  提交时间：2019/01/08
Thyroid hormone receptor β1 suppresses proliferation and migration by inhibiting PI3K/Akt signaling in human colorectal cancer cells 期刊论文
Oncology reports, 2016, 卷号: 36, 期号: 3, 页码: 1419-26
作者:  Zhu, Lei;  Tian, Guangang;  Yang, Qin;  De, Gejing;  Zhang, Zhigang
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase 期刊论文
ACTA PHARMACEUTICA SINICA B, 2016, 卷号: 6, 期号: 1, 页码: 32-45
作者:  Zhou, Yu;  Liu, Jun;  Zheng, Mingyue;  Zheng, Shuli;  Jiang, Chunyi
收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08
structuraloptimizationandbiologicalevaluationofl5disubstitutedpyrazole3carboxaminesaspotentinhibitorsofhuman5lipoxygenase 期刊论文
actapharmaceuticasinicab, 2016, 卷号: 6, 期号: 1, 页码: 32
作者:  Zhou Yu;  Liu Jun;  Zheng Mingyue;  Zheng Shuli;  Jiang Chunyi
收藏  |  浏览/下载：5/0  |  提交时间：2020/07/01
Structural optimization and biological evaluation of l,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase 期刊论文
Acta Pharmaceutica Sinica B, 2016, 卷号: 6, 期号: 1, 页码: 32
作者:  Zhou Yu;  Liu Jun;  Zheng Mingyue;  Zheng Shuli;  Jiang Chunyi
收藏  |  浏览/下载：20/0  |  提交时间：2020/12/24
2,4-Diarylamino-pyrimidines as kinase inhibitors co-targeting IGF1R and EGFR(L858R/T790M) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 19, 页码: 4277-4281
作者:  Chan, Shingpan;  Han, Kun;  Qu, Rong;  Tong, Linjiang;  Li, Yingjun
收藏  |  浏览/下载：47/0  |  提交时间：2019/01/08
C5-substituted pyrido[2,3-d]pyrimidin-7-ones as highly specific kinase inhibitors targeting the clinical resistance-related EGFR(T790M) mutant 期刊论文
MEDCHEMCOMM, 2015, 卷号: 6, 期号: 9, 页码: 1693-1697
作者:  Xu, Tianfeng;  Peng, Ting;  Ren, Xiaomei;  Zhang, Lianwen;  Yu, Lei
收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08
Design, Synthesis, and Biological Evaluation of Novel Conformationally Constrained Inhibitors Targeting Epidermal Growth Factor Receptor Threonine(790) -> Methionine(790) Mutant 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 55, 期号: 6, 页码: 2711-2723
作者:  Chang, Shaohua;  Zhang, Lianwen;  Xu, Shilin;  Luo, Jinfeng;  Lu, Xiaoyun
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08

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