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科研机构
上海药物研究所 [57]
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期刊论文 [57]
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2021 [5]
2020 [5]
2019 [3]
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GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhang, Qing
;
Chen, Lin-hai
;
Yang, Hui
;
Fang, You-chen
;
Wang, Si-wei
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/01/18
GPR84
medium chain fatty acid receptor
GPCR
inflammatory bowel diseases
ulcerative colitis
NLRP3 inflammasome
macrophages
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2021/08/17
Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 37, 页码: 16
作者:
Yang, Gui-Xiang
;
Sun, Jia-Min
;
Zheng, Lu-Lu
;
Zhang, Li
;
Li, Jie
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2021/06/11
Vascular dementia
Diosgenin
Antioxidant
Anti-cholinesterase
Multi-target-directed ligands
Development of a nanobody-based immunoassay for the sensitive detection of fibrinogen-like protein 1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhang, Wan-ting
;
Liu, Ting-ting
;
Wu, Man
;
Chen, Xiao-chen
;
Han, Li
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2021/05/24
nanobody
FGL1
cancer immunology
diagnosis
immune checkpoint
PI3K alpha inhibitor CYH33 triggers antitumor immunity in murine breast cancer by activating CD8(+)T cells and promoting fatty acid metabolism
期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 卷号: 9, 期号: 8, 页码: 16
作者:
Sun, Pu
;
Zhang, Xi
;
Wang, Rong-Jing
;
Ma, Qing-Yang
;
Xu, Lan
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/11/04
tumor microenvironment
immunomodulation
immunologic memory
lymphocytes
tumor-infiltrating
macrophages
Neuroprotective and Anti-inflammatory Ditetrahydrofuran-Containing Diarylheptanoids from Tacca chantrieri
期刊论文
JOURNAL OF NATURAL PRODUCTS, 2020, 卷号: 83, 期号: 12, 页码: 3681-3688
作者:
Yang, Yue
;
Gong, Qi
;
Wang, Wei
;
Mao, Ying-Le
;
Wang, Xiao-Rong
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2021/05/24
Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
He, Zhi-di
;
Zhang, Meng
;
Wang, Yong-hui
;
He, Yang
;
Wang, Hai-rui
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/05/24
tumor-targeted delivery
immunogenic cell death
PD-1
PD-L1 blockade
tumor immune microenvironment
irinotecan
JQ1
immune checkpoint
Photochromic Fluorescent Probe Strategy for the Super-resolution Imaging of Biologically Important Biomarkers
期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 卷号: 142, 期号: 42, 页码: 18005-18013
作者:
Chai, Xianzhi
;
Han, Hai-Hao
;
Sedgwick, Adam C.
;
Li, Na
;
Zang, Yi
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/24
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Su, Hai-xia
;
Yao, Sheng
;
Zhao, Wen-feng
;
Li, Min-jun
;
Liu, Jia
收藏
  |  
浏览/下载:115/0
  |  
提交时间:2020/12/24
SARS-CoV-2
3CL protease
traditional Chinese medicines
Shuanghuanglian oral liquid
baicalin
baicalein
Comparison of intramuscular and intravenous pharmacokinetics of ginsenosides in humans after dosing XueShuanTong, a lyophilized extract of Panax notoginseng roots
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 253, 页码: 7
作者:
Zhang, Hai-Yan
;
Niu, Wei
;
Olaleye, Olajide E.
;
Du, Fei-Fei
;
Wang, Feng-Qing
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
Ginsenoside
Pharmacokinetics
Intramuscular
Intravascular
XueShuanTong
Panay notoginseng roots
Sanqi
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