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科研机构
上海药物研究所 [221]
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期刊论文 [218]
会议论文 [3]
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2021 [20]
2020 [25]
2019 [15]
2018 [29]
2017 [21]
2016 [15]
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Chemistry [3]
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Discovery of a Potential Liver Fibrosis Inhibitor from a Mushroom Endophytic Fungus by Genome Mining of a Silent Biosynthetic Gene Cluster
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 38, 页码: 11303-11310
作者:
Cheng, Jin-Tao
;
Wang, Han-Min
;
Yu, Jia-Hui
;
Sun, Chen-Fan
;
Cao, Fei
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/12/01
fungus
Calcarisporium arbuscula
natural product
gene cluster activation
liver fibrosis
Engineering Chameleon Prodrug Nanovesicles to Increase Antigen Presentation and Inhibit PD-L1 Expression for Circumventing Immune Resistance of Cancer
期刊论文
ADVANCED MATERIALS, 2021, 页码: 12
作者:
Zhou, Fengqi
;
Gao, Jing
;
Tang, Yang
;
Zou, Zhifeng
;
Jiao, Shi
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/11/04
antigen presentation
autophagy inhibition
immune resistance
immunotherapy
prodrug nanovesicles
Competitive CatSper Activators of Progesterone from Rhynchosia volubilis
期刊论文
PLANTA MEDICA, 2021, 页码: 10
作者:
Xiang, Jin
;
Kang, Hang
;
Li, Hong-Gang
;
Shi, Yu-Long
;
Zhang, Ya-Li
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/11/04
Leguminosae
Rhynchosia volubilis
CatSper
prenylated isoflavonoids
rhynchones A - E
Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Huang, He-ming
;
Fan, Shi-jie
;
Zhou, Xiao-ru
;
Liu, Yan-jun
;
Li, Xiao
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/04
nonalcoholic steatohepatitis
inflammation
histone deacetylase inhibitor
givinostat
epigenetics
Design, synthesis, and antibacterial evaluation of vancomycin-LPS binding peptide conjugates
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 45, 页码: 8
作者:
Shi, Weiwei
;
Chen, Feifei
;
Zou, Xiangman
;
Jiao, Shang
;
Wang, Siqi
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/08/17
Vancomycin analogues
LPS binding peptides
Vancomycin-Peptide Conjugates
Antibacterial activity
Supramolecular Antagonists Promote Mitochondrial Dysfunction
期刊论文
NANO LETTERS, 2021, 卷号: 21, 期号: 13, 页码: 5730-5737
作者:
Li, Mingming
;
Song, Yanqiu
;
Song, Na
;
Wu, Guangyao
;
Zhou, Hao
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2021/08/17
Self-Assembly
Peptides
Drug Delivery
Mitochondrion-Targeting
Antagonists
Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9217-9237
作者:
Liang, Xuewu
;
Sun, Chenxia
;
Li, Chunpu
;
Yu, Haolan
;
Wei, Xiaohui
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/08/17
A facile method for vancomycin C-terminus functionalization and derivatization through hydrazide
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 42, 页码: 6
作者:
Hu, Yu
;
Zou, Xiangman
;
Shi, Weiwei
;
Ma, Chenhui
;
Chen, Feifei
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/08/17
Vancomycin C-terminus modification
Hydrazide derivatives
Native Chemical Ligation
Antibacterial activity
Activating Adenosine Monophosphate-Activated Protein Kinase Mediates Fibroblast Growth Factor 1 Protection From Nonalcoholic Fatty Liver Disease in Mice
期刊论文
HEPATOLOGY, 2021, 卷号: 73, 期号: 6, 页码: 2206-2222
作者:
Lin, Qian
;
Huang, Zhifeng
;
Cai, Genxiang
;
Fan, Xia
;
Yan, Xiaoqing
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/08/17
A novel phosphoramide compound, DCZ0805, shows potent anti-myeloma activity via the NF-κB pathway
期刊论文
Cancer Cell International, 2021, 卷号: 21, 期号: 1
作者:
Gao,Xuejie
;
Li,Bo
;
Ye,Anqi
;
Wang,Houcai
;
Xie,Yongsheng
收藏
  |  
浏览/下载:97/0
  |  
提交时间:2021/06/11
Multiple myeloma
Anti-tumor activity
NF-κB
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