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科研机构
上海药物研究所 [17]
内容类型
期刊论文 [16]
会议论文 [1]
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2021 [2]
2020 [2]
2019 [3]
2017 [1]
2016 [1]
2010 [1]
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Metabolic Study of Stable Isotope Labeled Indolinone Derivative in Hepatocyte Cell by UPLC/Q TOF MS
期刊论文
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2021, 卷号: 32, 期号: 6, 页码: 1538-1544
作者:
Yang, Jixia
;
Zhang, Gongzheng
;
Wang, Zhaoyang
;
Meng, Jian
;
Wen, Hongliang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/12/16
indolinone derivatives
alpha-synuclein
[C-3(2), N-15]-isotope labeling, metabolite
UPLC/QTOF
Aha1 Exhibits Distinctive Dynamics Behavior and Chaperone-Like Activity
期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 7, 页码: 20
作者:
Hu, Huifang
;
Wang, Qing
;
Du, Jingwen
;
Liu, Zhijun
;
Ding, Yiluan
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/05/24
Aha1
NMR
dynamics
chaperone-like activity
α
-synuclein
Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 4, 页码: 483-498
作者:
Xu, Ming-ming
;
Ryan, Philip
;
Rudrawar, Santosh
;
Quinn, Ronald J.
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
advancesinthedevelopmentofimagingprobesandaggregationinhibitorsforalphasynuclein
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 4, 页码: 483
作者:
Xu Mingming
;
Ryan Philip
;
Rudrawar Santosh
;
Quinn Ronald J
;
Zhang Haiyan
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Parkinson’s disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
Caffeic acid reduces A53T alpha-synuclein by activating JNK/Bcl-2-mediated autophagy in vitro and improves behaviour and protects dopaminergic neurons in a mouse model of Parkinson's disease
期刊论文
PHARMACOLOGICAL RESEARCH, 2019, 卷号: 150, 页码: 14
作者:
Zhang, Yu
;
Wu, Qimei
;
Zhang, Lei
;
Wang, Qing
;
Yang, Zexian
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Caffeic acid
A53T
Parkinson's disease
Autophagy
JNK
Neuroprotective Effects of Ginseng Phytochemicals: Recent Perspectives
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 16, 页码: 20
作者:
Huang, Xing
;
Li, Ning
;
Pu, Yiqiong
;
Zhang, Tong
;
Wang, Bing
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
neuroprotective effects
ginseng
Alzheimer's disease
ginsenoside
Parkinson's disease
Identification of a New alpha-Synuclein Aggregation Inhibitor via Mass Spectrometry Based Screening
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 6, 页码: 2683-2691
作者:
Xu, Mingming
;
Loa-Kum-Cheung, Wendy
;
Zhang, Haiyan
;
Quinn, Ronald J.
;
Mellick, George D.
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
aggregation
mass spectrometry
screening
inhibitor
Nuclear Accumulation of Histone Deacetylase 4 (HDAC4) Exerts Neurotoxicity in Models of Parkinson's Disease
期刊论文
MOLECULAR NEUROBIOLOGY, 2017, 卷号: 54, 期号: 9, 页码: 6970-6983
作者:
Wu, Qimei
;
Yang, Xiaoyu
;
Zhang, Lei
;
Zhang, Yu
;
Feng, Linyin
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
HDAC4
alpha-Synuclein
Neuroprotection
Parkinson's disease
PKC
Chronic mild stress accelerates the progression of Parkinson's disease in A53T alpha-synuclein transgenic mice
期刊论文
EXPERIMENTAL NEUROLOGY, 2016, 卷号: 285, 页码: 61-71
作者:
Wu, Qimei
;
Yang, Xiaoyu
;
Zhang, Yu
;
Zhang, Lei
;
Feng, Linyin
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Chronic mild stress
Parkinson's disease
alpha-synuclein
Dopamine
Microglia
Interaction with synphilin-1 promotes inclusion formation of alpha-synuclein: mechanistic insights and pathological implication
期刊论文
FASEB JOURNAL, 2010, 卷号: 24, 期号: 1, 页码: 196-205
作者:
Xie, Yuan-Yuan
;
Zhou, Chen-Jie
;
Zhou, Zi-Ren
;
Hong, Jing
;
Che, Mei-Xia
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2019/01/08
coiled coil
solution structure
Parkinson's disease
Lewy body
dimerization
N-terminal stretch
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