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浏览/检索结果:
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学科主题:Biochemistry & Molecular Biology
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Large Conformational Changes of Insertion 3 in Human Glycyl-tRNA Synthetase (hGlyRS) during Catalysis
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 卷号: 291, 期号: 11, 页码: 5740-5752
作者:
Deng, Xiangyu
;
Qin, Xiangjing
;
Chen, Lei
;
Jia, Qian
;
Zhang, Yonghui
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2016/12/26
aminoacyl tRNA synthetase
Charcot-Marie-Tooth disease (CMT)
conformational change
crystal structure
enzyme mechanism
High-throughput screening-compatible assays of As(III) S-adenosylmethionine methyltransferase activity
期刊论文
ANALYTICAL BIOCHEMISTRY, 2015, 卷号: 480, 页码: 67-73
作者:
Dong, Hui
;
Xu, Wenzhong
;
Pillai, Jitesh K.
;
Packianathan, Charles
;
Rosen, Barry P.
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  |  
浏览/下载:8/0
  |  
提交时间:2022/09/13
Arsenic
Methylation
AS3MT
High-throughput screens
Subdomain II of alpha-Isopropylmalate Synthase Is Essential for Activity INFERRING A MECHANISM OF FEEDBACK INHIBITION
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 卷号: 289, 期号: 40, 页码: 27966-27978
作者:
Zhang, ZL
;
Wu, J
;
Lin, W
;
Wang, J
;
Yan, H
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  |  
浏览/下载:61/0
  |  
提交时间:2015/07/22
Allosteric Regulation
Cooperativity
Enzyme Catalysis
Enzyme Structure
Protein Conformation
Catalytic Module
Feedback Inhibition
A bridge between the aminoacylation and editing domains of leucyl-tRNA synthetase is crucial for its synthetic activity
期刊论文
RNA-A PUBLICATION OF THE RNA SOCIETY, 2014, 卷号: 20, 期号: 9, 页码: 1440-1450
作者:
Huang, Q
;
Zhou, XL
;
Hu, QH
;
Lei, HY
;
Fang, ZP
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  |  
浏览/下载:17/0
  |  
提交时间:2015/07/22
Homo sapiens cytoplasm
leucyl-tRNA synthetase
CP1 hairpin
amino acid activation
aminoacylation
tRNA binding
The tRNA recognition mechanism of the minimalist SPOUT methyltransferase, TrmL
期刊论文
NUCLEIC ACIDS RESEARCH, 2013, 卷号: 41, 期号: 16, 页码: 7828-7842
作者:
Liu, RJ
;
Zhou, M
;
Fang, ZP
;
Wang, M
;
Zhou, XL
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  |  
浏览/下载:12/0
  |  
提交时间:2015/07/22
Structures of trans-2-enoyl-00A reductases from Clostridium acelobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
期刊论文
BIOCHEMICAL JOURNAL, 2013, 卷号: 449, 期号: 1, 页码: 79-89
作者:
Hu, K
;
Zhao, M
;
Zhang, TL
;
Zha, MW
;
Zhong, C
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  |  
浏览/下载:22/0
  |  
提交时间:2015/07/22
biofuel
catalytic mechanism
crystal structure
reductase
substrate specificity
synthetic biology
Insights into the Catalytic Mechanism of 16S rRNA Methyltransferase RsmE (m(3)U1498) from Crystal and Solution Structures
期刊论文
JOURNAL OF MOLECULAR BIOLOGY, 2012, 卷号: 423, 期号: 4, 页码: 576-589
作者:
Zhang H(张衡)
;
Zhang, H
;
Gao ZQ(高增强)
;
Wan, H
;
Gao, ZQ
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  |  
浏览/下载:28/0
  |  
提交时间:2016/04/08
RNA methylation
methyltransferase
PUA domain
trefoil knot
dimerization
Microbial biotransformation of water-insoluble herbimycin A to 11-hydroxy-(11-demethoxy)-herbimycin C by Eupenicillium sp SD017
期刊论文
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC, 2010, 卷号: 62, 期号: 1, 页码: 76-80
作者:
Xie, LW
;
Wang, GH
;
Zhang, H
;
Ouyang, YC
;
Sun, W
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2011/07/02
Herbimycin a
Biotransformation
Water-insoluble Anti-tumor Drug
O-demethylase
tRNA-dependent Pre-transfer Editing by Prokaryotic Leucyl-tRNA Synthetase
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 卷号: 285, 期号: 5, 页码: 3235-3244
作者:
Tan, M
;
Zhu, B
;
Zhou, XL
;
He, R
;
Chen, X
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  |  
浏览/下载:11/0
  |  
提交时间:2015/07/22
The Mechanisms of Human Hotdog-fold Thioesterase 2 (hTHEM2) Substrate Recognition and Catalysis Illuminated by a Structure and Function Based Analysis
期刊论文
BIOCHEMISTRY, 2009, 卷号: 48, 期号: 6, 页码: 1293-1304
Cao, Jian
;
Xu, Hang
;
Zhao, Hong
;
Gong, Weimin
;
龚为民
;
DunawayMariano, Debra
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  |  
浏览/下载:8/0
  |  
提交时间:2013/12/25
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