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浏览/检索结果: 共18条，第1-10条 帮助 限定条件 发表日期：2021     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Zhang, Qing;  Chen, Lin-hai;  Yang, Hui;  Fang, You-chen;  Wang, Si-wei 收藏  |  浏览/下载：45/0  |  提交时间：2022/01/18 GPR84  medium chain fatty acid receptor  GPCR  inflammatory bowel diseases  ulcerative colitis  NLRP3 inflammasome  macrophages   Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site 期刊论文 ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452 作者:  Wang, Jiang;  Yang, Dehua;  Cheng, Xi;  Yang, Linlin;  Wang, Zhaohui 收藏  |  浏览/下载：27/0  |  提交时间：2022/01/04 Constitutive signal bias mediated by the human GHRHR splice variant 1 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10 作者:  Cong, Zhaotong;  Zhou, Fulai;  Zhang, Chao;  Zou, Xinyu;  Zhang, Huibing 收藏  |  浏览/下载：26/0  |  提交时间：2021/12/01 class B1 GPCR  receptor bias  cancer  cell proliferation   Structures of full-length glycoprotein hormone receptor signalling complexes 期刊论文 NATURE, 2021, 页码: 24 作者:  Duan, Jia;  Xu, Peiyu;  Cheng, Xi;  Mao, Chunyou;  Croll, Tristan 收藏  |  浏览/下载：53/0  |  提交时间：2021/11/04 Different conformational responses of the beta(2)-adrenergic receptor-Gs complex upon binding of the partial agonist salbutamol or the full agonist isoprenaline 期刊论文 NATIONAL SCIENCE REVIEW, 2021, 卷号: 8 作者:  Yang, Fan;  Ling, Shenglong;  Zhou, Yingxin;  Zhang, Yanan;  Lv, Pei 收藏  |  浏览/下载：43/0  |  提交时间：2021/11/01 cryo-EM structure  G protein-coupled receptor (GPCR)  partial and full agonists  conformational change  desensitization   Structural mechanism of calcium-mediated hormone recognition and G beta interaction by the human melanocortin-1 receptor 期刊论文 CELL RESEARCH, 2021, 页码: 11 作者:  Ma, Shanshan;  Chen, Yan;  Dai, Antao;  Yin, Wanchao;  Guo, Jia 收藏  |  浏览/下载：24/0  |  提交时间：2021/11/04 Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 15 作者:  Lu, Shaoyong;  He, Xinheng;  Yang, Zhao;  Chai, Zongtao;  Zhou, Shuhua 收藏  |  浏览/下载：35/0  |  提交时间：2021/11/04 Discovery of Novel Allosteric Modulators Targeting an Extra-Helical Binding Site of GLP-1R Using Structure- and Ligand-Based Virtual Screening 期刊论文 BIOMOLECULES, 2021, 卷号: 11, 期号: 7, 页码: 14 作者:  Zhou, Qingtong;  Guo, Wanjing;  Dai, Antao;  Cai, Xiaoqing;  Vass, Marton 收藏  |  浏览/下载：41/0  |  提交时间：2021/08/17 GLP-1R  virtual screening  allosteric modulator  drug discovery  molecular docking   Structures of G(i)-bound metabotropic glutamate receptors mGlu2 and mGlu4 期刊论文 NATURE, 2021, 卷号: 594, 期号: 7864, 页码: 583-+ 作者:  Lin, Shuling;  Han, Shuo;  Cai, Xiaoqing;  Tan, Qiuxiang;  Zhou, Kexiu 收藏  |  浏览/下载：37/0  |  提交时间：2021/11/16 Structures of human mGlu2 and mGlu7 homo- and heterodimers 期刊论文 NATURE, 2021, 卷号: 594, 期号: 7864, 页码: 589-+ 作者:  Du, Juan;  Wang, Dejian;  Fan, Hongcheng;  Xu, Chanjuan;  Tai, Linhua 收藏  |  浏览/下载：26/0  |  提交时间：2021/08/17