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浏览/检索结果: 共304条，第1-10条 帮助 限定条件 发表日期：2016    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Deep Phosphoproteomic Measurements Pinpointing Drug Induced Protective Mechanisms in Neuronal Cells 期刊论文 FRONTIERS IN PHYSIOLOGY, 2016, 卷号: 7 作者:  Yu, Chengli;  Gao, Jing;  Zhou, Yanting;  Chen, Xiangling;  Xiao, Ruoxuan 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 phosphoproteomics  Alzheimer's disease  drug effect  mass spectrometry  neutronal cells   Design, Synthesis, and Pharmacological Evaluation of 2-(2,5-Dimethyl-5,6,7,8-tetrahydroquinolin-8-yl)-N-aryl Propanamides as Novel Smoothened (Smo) Antagonists 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 24, 页码: 11050-11068 作者:  Liu, Gang;  Xue, Ding;  Yang, Jun;  Wan, Juan;  Liu, Xiaohua 收藏  |  浏览/下载：54/0  |  提交时间：2019/01/08 Miltirone protects human EA.hy926 endothelial cells from oxidized low-density lipoprotein-derived oxidative stress via a heme oxygenase-1 and MAPK/Nrf2 dependent pathway 期刊论文 PHYTOMEDICINE, 2016, 卷号: 23, 期号: 14, 页码: 1806-1813 作者:  Zhang, Liu;  Zhang, Hui;  Li, Xueyan;  Jia, Bingjie;  Yang, Yuyu 收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 Miltirone  Nrf2  HO-1  Endothelial dysfunction  Oxidative stress   Elucidating the druggable interface of protein-protein interactions using fragment docking and coevolutionary analysis 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 卷号: 113, 期号: 50, 页码: E8051-E8058 作者:  Bai, Fang;  Morcos, Faruck;  Cheng, Ryan R.;  Jiang, Hualiang;  Onuchic, Jose N. 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 protein-protein interface  druggable surface  hot spots  direct coupling analysis  drug design   Functional human induced hepatocytes (hiHeps) with bile acid synthesis and transport capacities: A novel in vitro cholestatic model 期刊论文 Scientific Reports, 2016, 卷号: 6 作者:  Ni, Xuan;  Gao, Yimeng;  Wu, Zhitao;  Ma, Leilei;  Chen, Chen 收藏  |  浏览/下载：48/0  |  提交时间：2019/01/08 Scrodentoids F-I, four C-19-norditerpenoids from Scrophularia dentata 期刊论文 TETRAHEDRON, 2016, 卷号: 72, 期号: 49, 页码: 8031-8035 作者:  Zhang, Liu-qiang;  Zhao, Yuan-yuan;  Huang, Cheng;  Chen, Kai-xian;  Li, Yi-ming 收藏  |  浏览/下载：72/0  |  提交时间：2019/01/08 Scrophularia dentata  C-19-Norditerpenoids  Scrodentoids F-I  X-ray crystallography  FXR agonistic effect   Gsy, a novel glucansucrase from Leuconostoc mesenteroides, mediates the formation of cell aggregates in response to oxidative stress 期刊论文 SCIENTIFIC REPORTS, 2016, 卷号: 6 作者:  Yan, Minghui;  Han, Jin;  Xu, Xiaofen;  Liu, Lianliang;  Gao, Caixia 收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08 Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis 期刊论文 CELL RESEARCH, 2016, 卷号: 26, 期号: 12, 页码: 1330-1344 作者:  Zhang, Lin;  Xiao, Jianfeng;  Xu, Jianrong;  Fu, Tianran;  Cao, Zhiwei 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 fatty acid biosynthesis  dehydratase  ACP  complex structure   Stereoselective and Regioselective Preparation of C-Pentopyranosides and Formal Synthesis of Omarigliptin 期刊论文 EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 期号: 34, 页码: 5624-5628 作者:  Liu, Tongchao;  Hou, Jian;  Xie, Wuchen;  Li, You;  Ren, Huanming 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Asymmetric synthesis  C-glycosides  Drug design  Epoxides  Glycosylation   Rearranged diterpenoids from the seeds of Caesalpinia sappan 期刊论文 CHINESE CHEMICAL LETTERS, 2016, 卷号: 27, 期号: 12, 页码: 1751-1754 作者:  Xiao, Fang;  Tang, Chun-Ping;  Ke, Chang-Qiang;  Yao, Sheng;  Ye, Yang 收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08 Diterpenoid  Tomocinol C  Spirocaesalmin C  Caesalpinia sappan  Absolute configuration  X-ray crystallography