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武汉大学 [6]
西安交通大学 [4]
上海药物研究所 [4]
暨南大学 [4]
复旦大学上海医学院 [4]
华中师范大学 [2]
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期刊论文 [25]
学位论文 [6]
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W2476 represses TXNIP transcription via dephosphorylation of FOXO1 at Ser319
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2021, 页码: 11
作者:
Zhong, Li
;
Liu, Qing
;
Liu, Qiaofeng
;
Zhang, Shikai
;
Cao, Yongbing
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
chromatin immunoprecipitation
diabetes
transcription
TXNIP
W2476
Resveratrol Suppresses A beta-Induced Microglial Activation Through the TXNIP/TRX/NLRP3 Signaling Pathway
期刊论文
DNA AND CELL BIOLOGY, 2019, 卷号: 38, 期号: 8
作者:
Feng, Lifang
;
Zhang, Lingli
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/05
resveratrol
amyloid-beta protein
activation
neuroinflammation
TXNIP
TRX
NLRP3
Resveratrol protects human renal proximal tubular cells from high glucose and hypoxia/reoxygenation induced injury via inhibiting p38-MAPK and thioredoxin-interacting protein (TXNIP) pathways
期刊论文
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2019, 卷号: 12, 期号: 3
作者:
Xiao, Yeda
;
Yang, Yingcong
;
Cao, Hong
;
Huang, Yayi
;
Wang, Huaxin
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
Resveratrol
p38-MAPK/TXNIP
oxidative stress
inflammatory mediator
high-glucose
hypoxia-oxygenation injury
Dl-3-n-Butylphthalide Inhibits NLRP3 Inflammasome and Mitigates Alzheimer's-Like Pathology via Nrf2-TXNIP-TrX Axis
期刊论文
Antioxidants & Redox Signaling, 2019, 卷号: Vol.30 No.11, 页码: 1411-1431
作者:
Chun-Yan Wang
;
Ye Xu
;
Xu Wang
;
Chuang Guo
;
Tao Wang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/13
Alzheimer's disease
APP/PS1 transgenic mouse
Nrf2-TXNIP-TrX axis
Dl-NBP
NLRP3 inflammasome
Protective effect of ginsenoside metabolite compound K against diabetic nephropathy by inhibiting NLRP3 inflammasome activation and NF-kappa B/p38 signaling pathway in high-fat diet/streptozotocin-induced diabetic mice
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 卷号: 63
作者:
Song, Wu
;
Wei, Lin
;
Du, Yanwei
;
Wang, Yimei
;
Jiang, Shuang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Compound K
Nox1
TXNIP
NLRP3
Diabetic nephropathy
p38
Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis
期刊论文
Redox Biology, 2018, 卷号: 16, 页码: 32-46
作者:
Han, Yachun
;
Xu, Xiaoxuan
;
Tang, Chengyuan
;
Gao, Peng
;
Chen, Xianghui
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/12/03
ALT
alanine aminotransferase
AST
aspartate aminotransferase
BUN
blood urea nitrogen
BW
body weight
BG
blood glucose
DCFDA
dichlorodihydrofluorescein diacetate
DN
diabetic nephropathy
ECL
enhanced chemiluminescence
EM
electron microscopy
EMT
epithelial–mesenchymal transition
HbA1C
hemoglobin A1c
HE
hematoxylin-eosin
IF
immunofluorescence
IHC
immunohistochemistry
KW
kidney weight
LDL
low-density lipoprotein
MDA
malondialdehyde
MFI
median fluorescence intensity
MMP
mitochondrial transmembrane potential
MMT
methyl methane-thiosulphonate
MPTP
mitochondrial permeability transition pore
MSU
monosodium urate
MtROS
mitochondria reactive oxygen species
PAS
periodic acid-Schiff
Scr
serum creatinine
TC
total cholesterol
TG
triglyceride
TBARS
thiobarbituric acid reactive substances
TPP
triphenylphosphonium
TRX
thioredoxin
TXNIP
thioredoxin-interacting protein
TUNEL
terminal deoxynucleotidyl transferase dUTP nick end-labeling
8-OHdG
8-oxo-deoxyguanosine
UA
uric acid
Diabetic nephropathy
Mitochondria
Reactive oxygen species (ROS)
TRX/TXNIP
NLRP3 inflammasome
MitoQ
TXNIP knockdown alleviates hepatocyte ischemia reperfusion injury through preventing p38/JNK pathway activation
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 502, 页码: 409-414
作者:
Zhang, Yong
;
Miao, Liang-Sheng
;
Cai, Ying-Min
;
He, Jia-Xuan
;
Zhang, Zhen-Ni
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/11/26
TXNIP
Hepatic ischemia reperfusion injury
Cell apoptosis
p38/JNK pathway
c-Myc-driven glycolysis via TXNIP suppression is dependent on glutaminase-MondoA axis in prostate cancer
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 504, 页码: 415-421
作者:
Qu, Xuan
;
Sun, Jing
;
Zhang, Yami
;
Li, Jun
;
Hu, Junbi
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/26
Prostate cancer
c-Myc
Glutaminolysis
MondoA
TXNIP
Glutaminase
Icariin Ameliorates Palmitate-Induced Insulin Resistance Through Reducing Thioredoxin-Interacting Protein (TXNIP) and Suppressing ER Stress in C2C12 Myotubes
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Li, Mingxin
;
Zhang, Yemin
;
Cao, Yingkang
;
Zhang, Deling
;
Liu, Le
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
icariin
insulin resistance
TXNIP
proteasome
skeletal muscle cells
Verapamil Ameliorates Hepatic Metaflammation by Inhibiting Thioredoxin-Interacting Protein/NLRP3 Pathways
期刊论文
FRONTIERS IN ENDOCRINOLOGY, 2018, 卷号: 9
作者:
Zhou, Feng
;
Zhang, Ying
;
Chen, Jing
;
Hu, Yimeng
;
Xu, Yancheng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
hepatic metaflammation
NLRP3 inflammasome
non-alcoholic fatty liver disease
verapamil
thioredoxin-interacting protein(TXNIP)
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