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CORC

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Acetaldehyde induces similar cytotoxic and genotoxic risks in BEAS-2B cells and HHSteCs: involvement of differential regulation of MAPK/ERK and PI3K/AKT pathways 期刊论文
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2023, 卷号: 30
作者:  Zhang, Jingni;  Wang, Hongjuan;  Chen, Huan;  Liu, Yong;  Wang, An
收藏  |  浏览/下载：123/0  |  提交时间：2023/11/17
二苯乙烯类化合物对胰岛素抵抗HepG2细胞糖脂代谢紊乱的改善作用 期刊论文
中国药理学通报, 2023, 卷号: 39, 期号: 09, 页码: 1746-1754
作者:  马宏婷;  铁芳芳;  王瑞楠;  胡娜;  王洪伦
收藏  |  浏览/下载：0/0  |  提交时间：2023/12/01
Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma 期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:  Chen, Zi-qi;  Cao, Zhe-rui;  Wang, Yi;  Zhang, Xi;  Xu, Lan
收藏  |  浏览/下载：53/0  |  提交时间：2021/12/16
CYH33  MYC  P300  BET  B cell lymphoma  PI3K  
Low molecular weight fucoidan attenuating pulmonary fibrosis by relieving inflammatory reaction and progression of epithelial-mesenchymal transition 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 273, 页码: 10
作者:  Wu, Ning;  Li, Zhi;  Wang, Jing;  Geng, Lihua;  Yue, Yang
收藏  |  浏览/下载：57/0  |  提交时间：2021/12/02
Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9
作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu
收藏  |  浏览/下载：39/0  |  提交时间：2022/01/04
Rhodomeroterpene alleviates macrophage infiltration and the inflammatory response in renal tissue to improve acute kidney injury 期刊论文
FASEB JOURNAL, 2021, 卷号: 35, 期号: 11, 页码: 17
作者:  Wu, Yong-Mei;  Shi, Qing;  Zhu, Peng-Fei;  Ma, Hai-Jian;  Cui, Shi-Chao
收藏  |  浏览/下载：54/0  |  提交时间：2021/12/16
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Zhang, Xi;  Duan, Yu-ting;  Wang, Yi;  Zhao, Xing-dong;  Sun, Yi-ming
收藏  |  浏览/下载：36/0  |  提交时间：2021/05/24
FK228 sensitizes radioresistant small cell lung cancer cells to radiation 期刊论文
CLINICAL EPIGENETICS, 2021, 卷号: 13
作者:  Li, Hong;  Ma, Liying;  Bian, Xing;  Lv, Yang;  Lin, Wenchu
收藏  |  浏览/下载：47/0  |  提交时间：2021/04/26
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10
作者:  Xiang, Hao-Yue
收藏  |  浏览/下载：33/0  |  提交时间：2021/05/24
Discovery of 2-(5-(quinolin-6-yl)-1,3,4-oxadiazol-2-yl)acetamide derivatives as novel PI3K alpha inhibitors via docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 9
作者:  Gu, Dongyan;  Cheng, Gang;  Zhang, Mengmeng;  Zhou, Yu-Bo;  Li, Jia
收藏  |  浏览/下载：15/0  |  提交时间：2021/05/24

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