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科研机构
化学研究所 [1]
四川大学 [1]
华中师范大学 [1]
福州大学 [1]
兰州化学物理研究所 [1]
内容类型
期刊论文 [5]
发表日期
2018 [1]
2017 [1]
2016 [1]
2015 [1]
2001 [1]
学科主题
物理化学与绿色催化 [1]
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DFT investigation on the metabolic mechanisms of theophylline by cytochrome P450 monooxygenase
期刊论文
Journal of Molecular Graphics and Modelling, 2018, 卷号: Vol.84, 页码: 109-117
作者:
Fan Rao
;
Zeqin Chen
;
Dagang Zhou
;
Yuan Kang
;
Linfeng Guo
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/02/28
Theophylline
Cytochrome
P450
monooxygenase
N-demethylation
Density
functional
theory
Kinetic
isotope
effect
Acetic Acid Accelerated Visible-Light Photoredox Catalyzed N-Demethylation of N,N-Dimethylaminophenyl Derivatives
期刊论文
ADVANCED SYNTHESIS & CATALYSIS, 2017, 卷号: 359, 页码: 687-692
作者:
Wu, Guolin
;
Li, Yazhen
;
Yu, Xuemei
;
Gao, Yu
;
Chen, Haijun
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/21
practical
visible-light
photoredox catalyzed
N-demethylation
Detoxification of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) by cytochrome P450 enzymes: A theoretical investigation
期刊论文
Journal of Inorganic Biochemistry, 2016, 卷号: 154, 页码: 21-28
作者:
Li, Xiao-Xi
;
Wang, Yong
;
Zheng, Qing-Chuan
;
Zhang, Hong-Xing
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2016/02/02
Cytochrome P450 enzyme
Density functional calculations
N-demethylation
Aromatic hydroxylation
Epigenetic targets and drug discovery Part 2: Histone demethylation and DNA methylation
期刊论文
Pharmacology and Therapeutics, 2015, 卷号: 151, 页码: 121-140
作者:
Liu, Ke
;
Liu, Yanli
;
Lau, Johnathan L
;
Min, Jinrong*
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/23
Histone demethylation
DNA methylation
Inhibitor
Chemical probe
Drug discovery
LSD
lysine-specific histone demethylase
HDAC
histone deacetylase
REST
REST corepressor
DNMT
DNA methyltransferase
MAO
monoamine oxidase
AML
acute myeloid leukemia
KDM
lysine-specific demethylase
MLL
mixed lineage leukemia
FAD
flavin adenine dinucleotide
PCPA
trans-2-phenylcyclopropylamine
2,4-PDCA
2, 4-pyridinedicarboxylic acid
PHD
plant homeobox domain
SCLC
small cell lung cancer
JHDMs
JmjC-domain-containing histone demethylases
NOG
N-oxalylglycine
IOX1
5-carboxy-8-hydroxyquinoline
MDS
myelodysplastic syndrome
2-OG, 2-oxoglutarate or
α-ketoglutarate
G9a
euchromatic histone-lysine N-methyltransferase 2
CoREST complex
restin corepressor complex
SAH
S-adenosyl-l-homocysteine
l
SWI complex
ATP dependent chromatin remodeling complexes
Pan-Histone Demethylase Inhibitor
the inhibitor can simultaneously inhibit both LSDs and JHDMs
LSC colony
leukemic stem cell colony
Pan JmjC domain-containing demethylase inhibitor
the inhibitor can simultaneously inhibit all the members of JHDMs
E2F1
E2F transcription factor 1
E2F2
E2F transcription factor 2
RCC
renal cell carcinoma
Photooxidative N-demethylation of methylene blue in aqueous TiO2 dispersions under UV irradiation
期刊论文
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2001, 卷号: 140, 期号: 2, 页码: 163-172
作者:
Zhang, TY
;
Oyama, T
;
Aoshima, A
;
Hidaka, H
;
Zhao, JC
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/04/09
Methylene Blue
Photocatalytic Reaction
Titanium Dioxide
N-demethylation
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