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上海药物研究所 [7]
中国医学科学院 北京... [5]
山东大学 [4]
复旦大学上海医学院 [3]
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期刊论文 [23]
会议论文 [1]
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Design, Synthesis and Pharmacological Evaluation of Novel Hsp90N-terminal Inhibitors Without Induction of Heat Shock Response
期刊论文
CHEMISTRYOPEN, 2019, 卷号: 8, 期号: 3, 页码: 344-353
作者:
Liu, Peng
;
Chen, Xiangling
;
Zhu, Jianming
;
Li, Bo
;
Chen, Zhaoqiang
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
autophagy
Hsp72
Hsp90 inhibitor
triazines
antitumor activity
Recent Advances in the Discovery of Novel HSP90 Inhibitors: An Update from 2014
期刊论文
Current drug targets, 2019
作者:
Xiao Yan
;
Liu Yajun
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/02
HSP90
Anticancer
Drug design
HSP90 inhibitor
HSP90β GRP94
Lead optimization
HSP90 inhibitor DPB induces autophagy and more effectively apoptosis in A549 cells combined with autophagy inhibitors
期刊论文
IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2019, 卷号: 55, 期号: 5, 页码: 349-354
作者:
Zhao, YanChun
;
Li, Kunlun
;
Zhao, BaoXiang
;
Su, Le
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/11
HSP90 inhibitor
DPB
A549
Autophagy
Apoptosis
Discovery of Small-Molecule Inhibitors of the HSP90-Calcineurin-NFAT Pathway against Glioblastoma
期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 3, 页码: 352-3650000000
作者:
Liu, Zhenzhen
;
Li, Hongli
;
He, Lian
;
Xiang, Yu
;
Tian, Chengsen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
calcineurin
cancer therapy
cell signaling
click chemistry
drug screening
gene expression
glioblastoma
HSP90 inhibitor
NFAT
proteomics
Hsp90 beta inhibitors prevent GLT-1 degradation but have no beneficial efficacy on absence epilepsy
期刊论文
2019, 卷号: 21, 期号: 9, 页码: 905-915
作者:
Peng, Yu-Chen
;
Wang, Shan
;
Zhang, Yong
;
Huang, Long-Jian
;
Wang, Xiao-Liang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Hsp90 beta inhibitor
epilepsy
GLT-1
absence epilepsy
Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86
作者:
Geng, Kaijun
;
Liu, Hongchun
;
Song, Zilan
;
Zhang, Chi
;
Zhang, Minmin
收藏
  |  
浏览/下载:177/0
  |  
提交时间:2019/01/08
Heat shock protein 90 (Hsp90)
Tyrosine kinase ALK
Dual inhibitor
Drug resistance
Antiproliferative activity
Vibsane-Type Diterpenoids from Viburnum odoratissimum and Their Cytotoxic and HSP90 Inhibitory Activities
期刊论文
CHEMISTRY & BIODIVERSITY, 2018, 卷号: 15, 期号: 5, 页码: 1800049
作者:
Zhu, Qin-Feng
;
Qi, Yan-Yan
;
Zhang, Zhi-Jun
;
Fan, Min
;
Bi, Ran
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2018/07/16
Vibsane-type Diterpenoids
Viburnum Odoratissimum
Cytotoxicity
Hsp90 Inhibitor
In vitro interactions between 17-AAG and azoles against Exophiala dermatitidis
期刊论文
MYCOSES, 2018, 卷号: 61, 期号: 11
作者:
Gao, Lujuan
;
Sun, Yi
;
He, Chengyan
;
Li, Ming
;
Zeng, Tongxiang
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
17-AAG
azole
Exophiala dermatitidis
Hsp90 inhibitor
synergy
Image-guided photo-therapeutic nanoporphyrin synergized HSP90 inhibitor in patient-derived xenograft bladder cancer model
期刊论文
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2018, 卷号: 14, 期号: 3
作者:
Lam, Kit S.
;
Long, Qilai
;
Lin, Tzu-yin
;
Huang, Yee
;
Li, Xiaocen
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Photodynamic therapy
Photothermal therapy
HSP90 inhibitor
Bladder cancer
Nanoparticle
Discovery of novel HSP90 inhibitors that induced apoptosis and impaired autophagic flux in A549 lung cancer cells
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 551-558
作者:
Wei, Qun
;
Ning, Jun-Ya
;
Dai, Xi
;
Gao, Yuan-Di
;
Su, Le
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
Coumarin
Pyrazoline
HSP90 inhibitor
Lung cancer cell
Apoptosis
Autophagy
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