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科研机构
上海药物研究所 [1]
华南理工大学 [1]
华中师范大学 [1]
生态环境研究中心 [1]
内容类型
期刊论文 [3]
学位论文 [1]
发表日期
2019 [1]
2015 [2]
2014 [1]
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dynamicmodificationsofbiomacromoleculesmechanismandchemicalinterventions
期刊论文
sciencechinalifesciences, 2019, 卷号: 62, 期号: 11, 页码: 1459
作者:
Wang Chu
;
Zou Peng
;
Yang Caiguang
;
Liu Lei
;
Cheng Liang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
POSTTRANSLATIONAL MODIFICATIONS
PROTEIN LIPIDATION
DNA METHYLATION
TARGET
IDENTIFICATION
GLYCOSYLATION
CHEMISTRY
HEALTH
DYRK2
P53
chemical biology
biomacromolecule
dynamic modification
modification analysis
chemical intervention
Toxicity and DNA methylation changes induced by perfluorooctane sulfonate (PFOS) in sea urchin Glyptocidaris crenularis (EI收录)
期刊论文
Chemosphere, 2015, 卷号: 128, 页码: 225-230
作者:
Ding, Guanghui[1]
;
Wang, Luyan[1]
;
Zhang, Jing[2]
;
Wei, Yuanyuan[2]
;
Wei, Lie[1]
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  |  
浏览/下载:4/0
  |  
提交时间:2019/04/25
Alkylation
Chemical reactions
DNA
Mammals
Marine biology
Methylation
Organic pollutants
Oxygen
Toxicity
Epigenetic targets and drug discovery Part 2: Histone demethylation and DNA methylation
期刊论文
Pharmacology and Therapeutics, 2015, 卷号: 151, 页码: 121-140
作者:
Liu, Ke
;
Liu, Yanli
;
Lau, Johnathan L
;
Min, Jinrong*
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  |  
浏览/下载:13/0
  |  
提交时间:2019/12/23
Histone demethylation
DNA methylation
Inhibitor
Chemical probe
Drug discovery
LSD
lysine-specific histone demethylase
HDAC
histone deacetylase
REST
REST corepressor
DNMT
DNA methyltransferase
MAO
monoamine oxidase
AML
acute myeloid leukemia
KDM
lysine-specific demethylase
MLL
mixed lineage leukemia
FAD
flavin adenine dinucleotide
PCPA
trans-2-phenylcyclopropylamine
2,4-PDCA
2, 4-pyridinedicarboxylic acid
PHD
plant homeobox domain
SCLC
small cell lung cancer
JHDMs
JmjC-domain-containing histone demethylases
NOG
N-oxalylglycine
IOX1
5-carboxy-8-hydroxyquinoline
MDS
myelodysplastic syndrome
2-OG, 2-oxoglutarate or
α-ketoglutarate
G9a
euchromatic histone-lysine N-methyltransferase 2
CoREST complex
restin corepressor complex
SAH
S-adenosyl-l-homocysteine
l
SWI complex
ATP dependent chromatin remodeling complexes
Pan-Histone Demethylase Inhibitor
the inhibitor can simultaneously inhibit both LSDs and JHDMs
LSC colony
leukemic stem cell colony
Pan JmjC domain-containing demethylase inhibitor
the inhibitor can simultaneously inhibit all the members of JHDMs
E2F1
E2F transcription factor 1
E2F2
E2F transcription factor 2
RCC
renal cell carcinoma
光电及电化学发光传感器研究环境污染物导致的DNA特异性损伤
学位论文
博士, 北京: 中国科学院研究生院, 2014
作者:
吴一萍
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浏览/下载:108/0
  |  
提交时间:2015/06/25
光电化学DNA传感器
电化学发光DNA传感器
DNA化学甲基化
8-羟基脱氧鸟苷
碱基缺失
DNA糖基化
photoelectrochemical DNA snesor
electrochemiluminescence DNA sensor
DNA chemical methylation
8-oxo-7
8-dihydro-2'-deoxyguanosine
abasic sites
DNA glycosylase
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