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科研机构
中南大学 [7]
南华大学 [5]
复旦大学上海医学院 [4]
上海药物研究所 [3]
山东大学 [3]
清华大学 [1]
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期刊论文 [35]
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2019 [3]
2018 [2]
2017 [3]
2016 [2]
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Regulatory role of Golgi brefeldin A resistance factor-1 in amyloid precursor protein trafficking, cleavage and A beta formation
期刊论文
JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 卷号: 120, 期号: 9
作者:
Liu, Kaifei
;
Liu, Ying
;
Xu, Yanting
;
Nandakumar, Kutty Selva
;
Shen, Xiaoyan
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
amyloid precursor protein
beta-amyloid peptide
endoplasmic reticulum stress
Golgi brefeldin A resistance factor 1
transmembrane trafficking
Identification of inflammatory and vascular markers associated with mild cognitive impairment
期刊论文
AGING-US, 2019, 卷号: 11, 期号: 8
作者:
Shen, Xue-Ning
;
Lu, Yanxia
;
Tan, Crystal Tze Ying
;
Liu, Ling-Yun
;
Yu, Jin-Tai
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/12/05
mild cognitive impairment
TNF-alpha
C-peptide
VEGF-A
PAI-1
sTNFR-1
sIL-2R alpha
ROS/TRPA1/CGRP signaling mediates cortical spreading depression
期刊论文
JOURNAL OF HEADACHE AND PAIN, 2019, 卷号: 20
作者:
Jiang, Liwen
;
Ma, Dongqing
;
Grubb, Blair D.
;
Wang, Minyan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/11/19
Migraine
Transient receptor potential ankyrin a 1
Calcitonin gene-related peptide
Cortical spreading depression
Reactive oxygen species
ApoA-1 Mimetic Peptide ELK-2A2K2E Decreases Inflammatory Factor Levels Through the ABCA1-JAK2-STAT3-TTP Axis in THP-1-Derived Macrophages
期刊论文
Journal of Cardiovascular Pharmacology, 2018, 卷号: 72, 期号: 1, 页码: 60-67
作者:
Wang, Jia-Lin
;
Gong, Duo
;
Hu, Xin-Yan
;
Wu, Su
;
Zheng, Xi-Long
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
atherosclerosis
ABCA1
apoA-I mimetic peptide ELK-2A2K2E
inflammatory cytokines
Dietary supplementation of A-type procyanidins from litchi pericarp improves glucose homeostasis by modulating mTOR signaling and oxidative stress in diabetic ICR mice
期刊论文
Journal of Functional Foods, 2018, 卷号: 44, 页码: 155-165
作者:
Li, Xiaopeng
;
Wu, Qian
;
Sui, Yong
;
Li, Shuyi
;
Xie, Bijun
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/12/27
A-type procyanidins
Oxidative stress
Glucose homeostasis
Type 2 diabetes
mTOR
ACC1
acetyl coenzyme A carboxylase 1
ACL
ATP-citrate lyase
ALT
alanine aminotransferase
AST
aspartate aminotransferase
AUC
area under curve
BAT
brown adipose tissue
FAS
fatty acid synthase
FFA
free fatty acid
FoxO3a
Forkhead box O3a
FoxO1a
Forkhead box O3a
PKCβ
protein kinase C β
mTOR
mechanistic target of rapamycin
HDL
high-density lipoprotein
GHbA1c
glycated hemoglobin A1c
GK
glucokinase
G-6-Pase
glucose-6-phosphatase
GLP-1
glucagon-like peptide-1
GSH-PX
total glutathione peroxidase
HOMA-IR
homeostatic model assessment of insulin resistance
LDHA
lactate dehydrogenase
LDL
low-density lipoprotein
LPOPC
oligomeric procyanidins of litchi pericarp
MDA
malondialdehyde
MnSOD
manganese superoxide dismutase
mTOR
mechanistic target of rapamycin
OGTT
oral glucose tolerance test
PDH
pyruvate dehydrogenase
PEPCK
phosphoenolpyruvate carboxykinase
PFK
phosphofructokinase
PK
pyruvate kinase
PKCβ
protein kinase C β
PPG
postprandial blood glucose
S6K1
S6 Kinase 1
PKCβ
protein kinase C β
RTK
receptor tyrosine kinase
SREBP-1c
sterol regulatory element-binding protein 1c
ACL
ATP-citrate lyase
ACC1
acetyl coenzyme A carboxylase 1
FAS
fatty acid synthase
SCD1
stearoyl CoA desaturase 1
STZ
streptozotocin
S6K1
S6 kinase 1
PPG
postprandial blood glucose
ROS
reactive oxygen species
TC
total cholesterol
TG
triacylglycerol
STZ
streptozotocin
T-AOC
total antioxidant capacity
T-SOD
total superoxide dismutase
UCP-1
uncoupling protein 1
WAT
white adipose tissue
XOS
xylo-oligosaccharides
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
Epithelial cell adhesion molecule independent capture of non-small lung carcinoma cells with peptide modified microfluidic chip
期刊论文
BIOSENSORS & BIOELECTRONICS, 2017, 卷号: 89, 页码: 927-931
作者:
Pu, Kefeng[1]
;
Li, Chunlin[2]
;
Zhang, Nengpan[3]
;
Wang, Hui[4]
;
Shen, Wenjiang[5]
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/04/24
Circulating tumor cells
Epithelial-mesenchymal transition
A-1 peptide
Microfluidic chips
Apelin/APJ system: A bifunctional target for cardiac hypertrophy
期刊论文
International Journal of Cardiology, 2017, 卷号: 230, 页码: 164-170
作者:
Lu, Liqun
;
Wu, Di
;
Li, Lanfang*
;
Chen, Linxi*(陈临溪)
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
Apelin/APJ system
Cardiac hypertrophy
Oxidative stress
Obesity
Hypertension
Myocardial infarction
AT1R
angiotensin II type 1 receptor
Ang II
angiotensin II
PCSK3
proprotein convertase subtilisin/kexin3
5-HT
serotonin
TNF-α
tumor necrosis factor-a
HW/BW
the ratio of heart weight/body weight
ANP
atrial natriuretic peptide
LV
left ventricular
ANF
atrial natriuretic factor
TGF-β1
transforming growth factor beta1
ROS
reactive oxygen species
β-MHC
beta-myosin heavy chain
HFD
high-fat diet
ER
endoplasmic reticulum
FA
fatty acid
MI
myocardial infarction
ACE2
angiotensin-converting enzyme 2
LVH
left ventricular hypertrophy
1,25-DIHYDROXYVITAMIN D-3 REGULATES EXPRESSION OF LRP1 AND RAGE IN VITRO AND IN VIVO, ENHANCING A beta(1-40) BRAIN-TO-BLOOD EFFLUX AND PERIPHERAL UPTAKE TRANSPORT
期刊论文
Neuroscience, 2016, 卷号: 322, 页码: 28-38
作者:
Guo, Y-X
;
He, L-Y
;
Zhang, M
;
Wang, F
;
Liu, F
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
1,25(OH)2D3
1,25-dihydroxyvitamin D3
AD
Alzheimer’s disease
Aβ
amyloid-β
BBB
blood–brain barrier
bEnd.3
mouse brain microvascular endothelial cell lines
DMEM
Dulbecco’s modified Eagle’s medium
ELISA
enzyme-linked immunosorbent assay
FBS
fetal bovine serum
HepG2
human hepatoblastoma cell lines
HRP
horseradish peroxidase
LRP1
low-density lipoprotein receptor-related protein 1
RAGE
receptor for advanced glycation end products
RAP
receptor-associated peptide
TEER
transendothelial electrical resistance
VDR
vitamin D receptor
Alzheimer’s disease
1,25(OH)2D3
amyloid-β1–40
LRP1
RAGE
VDR
Synthesis and Functional Characterization of MAF-1A Peptide Derived From the Larvae of Housefly, Musca domestica (Diptera: Muscidae)
期刊论文
Journal of Medical Entomology, 2016, 卷号: 53, 期号: 6, 页码: 1467-1472
作者:
Zhou, Jing
;
Kong, Lina
;
Fang, Nainai
;
Mao, Bin
;
Ai, Hui*
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/23
*MAF-1A peptide
*Musca domestica L.
*antifungal activity
*antioxidant activity
*antiviral activity
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