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浏览/检索结果: 共4条，第1-4条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Olaparib hydroxamic acid derivatives as dual PARP and HDAC inhibitors for cancer therapy 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 页码: 4100-4109 作者:  Yuan, Zigao[1,2];  Chen, Shaopeng[2];  Sun, Qinsheng[2,3];  Wang, Ning[1,2];  Li, Dan[1,2] 收藏  |  浏览/下载：9/0  |  提交时间：2019/04/24 PARP  HDAC  Multitarget  Drug design  Antitumor   Design, synthesis and biological evaluation of 4-amidobenzimidazole acridine derivatives as dual PARP and Topo inhibitors for cancer therapy 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 138, 页码: 1135-1146 作者:  Yuan, Zigao[1,2];  Chen, Shaopeng[2];  Chen, Changjun[2];  Chen, Jiwei[1,2];  Chen, Chengken[1,2] 收藏  |  浏览/下载：8/0  |  提交时间：2019/04/24 Topo  PARP  Multitarget  Acridines  Antitumor bioactivity   Design, synthesis and anticancer potential of NSC-319745 hydroxamic acid derivatives as DNMT and HDAC inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 134, 页码: 281-292 作者:  Yuan, Zigao[1,2];  Sun, Qinsheng[2,3];  Li, Dan[1,2];  Miao, Shuangshuang[2];  Chen, Shaopeng[2] 收藏  |  浏览/下载：6/0  |  提交时间：2019/04/24 Epigenetic targets  Multi-target  Drug design  Antitumor bioactivity  DNMT  HDAC   Synthesis and biological research of novel azaacridine derivatives as potent DNA-binding ligands and topoisomerase II inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 页码: 3437-3446 作者:  Li, Dan[1,2,3];  Yuan, Zigao[1,2,3];  Chen, Shaopeng[2,3];  Zhang, Cunlong[3];  Song, Lu[1,2,3] 收藏  |  浏览/下载：6/0  |  提交时间：2019/04/24 Azaacridine derivatives  Molecular docking  DNA binding  Topoisomerase II inhibitor  Antiproliferative activity