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武汉大学 [18]
复旦大学上海医学院 [13]
上海药物研究所 [10]
中南大学 [7]
中国医学科学院 北京... [7]
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期刊论文 [96]
会议论文 [3]
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半导体器件 [2]
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Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9458-9483
作者:
Huang, Huoming
;
Li, Xueping
;
Xie, Peng
;
Li, Xinwei
;
Xu, XueJun
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/08/17
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:
Liu, Xiao
;
Jiang, Shuang
;
Kong, Linghui
;
Ye, Rongrong
;
Xiao, Li
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2021/05/24
Morphinans
arylacetamidyl substituent
kappa opioid receptor modulators
structure-activity relationships
Design, Synthesis, and Structure-Activity Relationship Exploration of Alkyl/Phenylalkyl Piperidine Analogues as Novel Highly Potent and Selective mu Opioid Receptor Agonists
期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 2, 页码: 285-299
作者:
Huang, Huoming
;
Li, Xinwei
;
Guo, Wei
;
Zhu, Chen
;
Qian, Yuanyuan
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
pain
opioid analgesic
SAR
selective MOR agonist
molecular dynamics simulations
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
期刊论文
AUTOPHAGY, 2021, 卷号: 17
作者:
Klionsky, Daniel J.
;
Abdel-Aziz, Amal Kamal
;
Abdelfatah, Sara
;
Abdellatif, Mahmoud
;
Abdoli, Asghar
收藏
  |  
浏览/下载:267/0
  |  
提交时间:2021/05/31
Autophagosome
cancer
flux
LC3
lysosome
macroautophagy
neurodegeneration
phagophore
stress
vacuole
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:
Xiao, Li
;
Wang, Yujun
;
Zhang, Mumei
;
Wu, Weiwei
;
Kong, Linghui
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2020/07/01
Single institution experience of split course radiotherapy in patients with desmoid tumors
期刊论文
ONCOTARGETS AND THERAPY, 2019, 卷号: 12
作者:
Luo, Jurui
;
Jin, Kairui
;
Qian, Shuizhang
;
Ma, Xuejun
;
Pan, Zigiang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
split course radiation
desmoid tumors
local control
Safety and Efficacy of Methotrexate for Chinese Adults With Psoriasis With and Without Psoriatic Arthritis
期刊论文
JAMA DERMATOLOGY, 2019, 卷号: 155, 期号: 3
作者:
Yan, Kexiang
;
Zhang, Yuanjing
;
Han, Ling
;
Huang, Qiong
;
Zhang, Zhenghua
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/12/05
Fine mapping and subphenotyping implicates ADRA1B gene variants in psoriasis susceptibility in a Chinese population
期刊论文
EPIGENOMICS, 2019, 卷号: 11, 期号: 4
作者:
Fan, Xing
;
Wang, Hongyan
;
Sun, Liangdan
;
Zheng, Xiaodong
;
Yin, Xianyong
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/12/05
ADRA1B
IL12B
mapping
psoriasis
psoriasis
PTTG1
SNP
subphenotyping analysis
susceptibility
variants
Enhanced toughness of bearing steel by combining prior cold deformation with martensite pre-quenching and bainite transformation
期刊论文
MATERIALS LETTERS, 2019, 卷号: 234, 页码: 5-8
作者:
Lu, Xiaohui
;
Qian, Dongsheng*
;
Li, Wei
;
Jin, Xuejun*
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/04
GCr15 bearing steel
Martensite-Bainite
Prior cold deformation
Toughness
Acoustic levitation and manipulation by a high-frequency focused ring ultrasonic transducer
期刊论文
APPLIED PHYSICS LETTERS, 2019, 卷号: 114, 期号: 5
作者:
Chen, Xiaoyang
;
Lam, Kwok Ho
;
Chen, Ruimin
;
Chen, Zeyu
;
Qian, Xuejun
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
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