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科研机构
山东大学 [12]
内容类型
期刊论文 [12]
发表日期
2018 [5]
2017 [4]
2016 [2]
2015 [1]
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Novel 5-methyl-2-phenylphenanthridium derivatives as FtsZ-targeting antibacterial agents from structural simplification of natural product sanguinarine
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 10, 页码: 1825-1831
作者:
Liu, Jingru
;
Ma, Ruxin
;
Bi, Fangchao
;
Zhang, Fa
;
Hu, Chaoyu
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/16
Antibacterial activity
FtsZ-targetingantibacterial agents
5-Methyl-2-phenylphenanthridium derivatives
Structural simplification
Design, synthesis and biological activity evaluation of novel 4-subtituted 2-naphthamide derivatives as AcrB inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 143, 页码: 699-709
作者:
Wang, Yinhu
;
Mowla, Rumana
;
Ji, Shengli
;
Guo, Liwei
;
Lopes, Miguel A. De Barros
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
2-Naphthamide
Antibiotic resistance
Drug efflux
Efflux pump inhibitor
Substitution of terminal amide with 1H-1,2,3-triazole: Identification of unexpected class of potent antibacterial agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 5, 页码: 884-891
作者:
Bi, Fangchao
;
Ji, Shengli
;
Venter, Henrietta
;
Liu, Jingru
;
Semple, Susan J.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/11
1H-1,2,3-Triazole
Terminal amide
Mimic
Antibacterial agents
In
silico prediction
Design, synthesis and structure-based optimization of novel isoxazole-containing benzamide derivatives as FtsZ modulators
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 159, 页码: 90-103
作者:
Bi, Fangchao
;
Song, Di
;
Zhang, Nan
;
Liu, Zhiyang
;
Gu, Xinjie
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/11
Isoxazole-containing benzamide
Antibacterial activity
FtsZ inhibitor
Molecular docking analysis
Structure-based optimization
Kinetic analysis of the inhibition of the drug efflux protein AcrB using surface plasmon resonance
期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2018, 卷号: 1860, 期号: 4, 页码: 878-886
作者:
Mowla, Rumana
;
Wang, Yinhu
;
Ma, Shutao
;
Venter, Henrietta
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/11
Multidrug resistance
Drug efflux
Efflux pump inhibitor
Affinity
constant
Surface plasmon resonance
AcrB
Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 4, 页码: 733-739
作者:
Wang, Yinhu
;
Mowla, Rumana
;
Guo, Liwei
;
Ogunniyi, Abiodun D.
;
Rahman, Taufiq
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/12
2-Naphthamide
Antimicrobial resistance
Efflux pump inhibitor
Drug
efflux pump
AcrB
Multidrug resistance
Design, synthesis and biological activity evaluation of novel 2,6-difluorobenzamide derivatives through FtsZ inhibition
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 4, 页码: 958-962
作者:
Bi, Fangchao
;
Guo, Liwei
;
Wang, Yinhu
;
Venter, Henrietta
;
Semple, Susan J.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/12
Benzamide derivatives
Design and synthesis
FtsZ inhibition
Biological
activity
Synthesis and antibacterial activity of novel 3-O-descladinosylazithromycin derivatives
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 127, 页码: 874-884
作者:
Yan, Mi
;
Ma, Ruixin
;
Jia, Li
;
Venter, Henrietta
;
Ma, Shutao
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/12
Antibacterial activity
3-O-Descladinosylazithromycin
Erythromycin-resistant bacteria
Synthesis
Synthesis and antibacterial activity of 5-methylphenanthridium derivatives as FtsZ inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 15, 页码: 3399-3402
作者:
Liu, Fang
;
Venter, Henrietta
;
Bi, Fangchao
;
Semple, Susan J.
;
Liu, Jingru
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/12
Antimicrobials
Biological evaluation
FtsZ
Structure-activity
relationships
5-Methylphenanthridium derivatives
Efflux Pump Inhibitors: A Novel Approach to Combat Efflux-Mediated Drug Resistance in Bacteria
期刊论文
CURRENT DRUG TARGETS, 2016, 卷号: 17, 期号: 6, 页码: 702-719
作者:
Wang, Yinhu
;
Venter, Henrietta
;
Ma, Shutao
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/16
Multi-drug resistance
efflux pumps
efflux pump inhibitors
NorA
MexAB-OprM
AcrAB-TolC
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