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The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1
期刊论文
出版物, 2111, 页码: 1-44
作者:
1M S Grace
;
T Lieu
;
B Darby
;
F C Abogadie
;
N Veldhuis N W Bunnett
;
P McIntyre
收藏
  |  
浏览/下载:226/0
  |  
提交时间:2017/07/24
Transient Receptor Potential Ion Channel
Trpv4
Protease Activated Receptor
Par2
Pain
Tyrosine Kinase
Bafetinib
Gefitinib enhances the anti-tumor immune response against EGFR-mutated NSCLC by upregulating B7H5 expression and activating T cells via CD28H
期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2022, 卷号: 61
作者:
Guo, Huihui
;
Zhang, Xilin
;
Xie, Shangzhi
;
Chen, Tianwei
;
Xie, Dong
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  |  
浏览/下载:19/0
  |  
提交时间:2022/12/22
gefitinib
CD28H
NSCLC
EGFR mutation
Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract
期刊论文
CANCER COMMUNICATIONS, 2022
作者:
Wu, Huanwen
;
Yu, Zicheng
;
Liu, Yueping
;
Guo, Lei
;
Teng, Lianghong
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  |  
浏览/下载:22/0
  |  
提交时间:2022/12/22
Neuroendocrine carcinomas
Gastrointestinal tract
Genomic characterization
Heterogeneity
Therapeutic implications
Associations Between Serum Reproductive Hormone Concentrations and Hormonal Receptor Status Among Postmenopausal Chinese Women With Breast Cancer: An Observational Study
期刊论文
FRONTIERS IN ONCOLOGY, 2022, 卷号: 12
作者:
Jiang, Chuner
;
Wu, Peng
;
He, Xiangming
;
Ni, Jianfen
;
Ding, Xiaowen
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/12/23
breast cancer
postmenopausal
reproductive hormones
estrogen receptor
progesterone receptor
HER2 receptor
Liquid chromatography-mass spectrometry based metabolic characterization of pleural effusion in patients with acquired EGFR-TKI resistance
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 202
作者:
Li, Na
;
Mao, Weimin
;
Gao, Yun
;
Wang, Ding
;
Song, Zhengbo
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/08/31
Lung cancer
EGFR-TKI
Resistance
Pleural effusion
Metabolomics
Biomarker
Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18
作者:
Xu, Dandan
;
Sun, Deqiao
;
Wang, Wei
;
Peng, Xia
;
Zhan, Zhengsheng
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  |  
浏览/下载:45/0
  |  
提交时间:2021/08/17
Axl
Cancer
Inhibitor
Pyrrolo[2,3-d]pyrimidine
PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy
期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12
作者:
Qi, Si-Min
;
Dong, Jinyun
;
Xu, Zhi-Yuan
;
Cheng, Xiang-Dong
;
Zhang, Wei-Dong
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  |  
浏览/下载:47/0
  |  
提交时间:2021/06/15
PROTAC
E3 ubiquitin ligase
protein degradation
ubiquitin-proteasome system
cancer therapy
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yu-ting
;
Ding, Hui-hua
;
Lin, Ze-min
;
Wang, Que
;
Chen, Li
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
rheumatoid arthritis
BTK inhibitors
B cells
macrophages
RANKL
osteoclastogenesis
Inhibition of B-cell receptor signaling disrupts cell adhesion in mantle cell lymphoma via RAC2
期刊论文
BLOOD ADVANCES, 2021, 卷号: 5, 期号: 1, 页码: 185-197
作者:
Wu, Wenjun
;
Wang, Weige
;
Franzen, Carrie A.
;
Guo, Hui
;
Lee, Jimmy
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/07/01
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:
Lai, Meng-zhen
;
Song, Pei-ran
;
Dou, Dou
;
Diao, Yan-yan
;
Tong, Lin-jiang
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  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
B cell receptor
Bruton's tyrosine kinase
ibrutinib
small-molecule inhibitor
B cell malignancies
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