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上海药物研究所 [41]
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长春应用化学研究所 [12]
合肥物质科学研究院 [11]
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期刊论文 [194]
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Proteomics Analysis Revealed Smad3 as a Potential Target of the Synergistic Anti-tumor Activity of Disulfiram and Cisplatin in Ovarian Cancer
期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23
作者:
Du, Ruiping
;
Sun, Feilong
;
Li, Kai
;
Qi, Jian
;
Zhong, Wen
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/11/10
Disulfiram
cisplatin resistance
ovarian cancer
proteomics analysis
SMAD3
lactate dehydrogenase
Darinaparsin (ZIO-101) enhances the sensitivity of small-cell lung cancer to PARP inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Guo-Zhen
;
Ma, Li-Ying
;
Zhang, Zong-Hui
;
Wang, Xiao-Lin
;
Hua, Jing-Han
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/22
small-cell lung cancer
H3
3
PARP1
PARP inhibitor
darinaparsin
combination treatment
Injectable magnetic montmorillonite colloidal gel for the postoperative treatment of hepatocellular carcinoma
期刊论文
JOURNAL OF NANOBIOTECHNOLOGY, 2022, 卷号: 20
作者:
Chen, Sheng
;
Song, Yonghong
;
Yan, Xu
;
Dong, Liang
;
Xu, Yunjun
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/12/23
Colloidal gel
Magnetic hyperthermia
Hepatocellular carcinoma
Postoperative therapy
Hemostasis
Key Considerations in Targeted Protein Degradation Drug Discovery and Development
期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:
Qin, Liena
;
Dai, Han
;
Wang, Junfeng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/12/23
targeted protein degradation
PROTAC
molecular glue
chemically induced proximity
drug discovery and development
Self-assembled Pt(II) metallacycles enable precise cancer combination chemotherapy
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119
作者:
Zhang, Pengge
;
Zhou, Zhixuan
;
Long, Wen
;
Yan, Yuping
;
Li, Youshan
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/12/22
self-assembly
supramolecular coordination complex
combination chemotherapy
targeted cancer therapy
drug delivery
Innovative Synthesis of PANI/Cu2O Nanocomposite and Its Antibacterial Properties**
期刊论文
CHEMISTRYSELECT, 2021, 卷号: 6, 期号: 47, 页码: 13636-13641
作者:
Zhang, Mengmeng
;
Han, Sha
;
Niu, Xiaohui
;
Li, Hongxia
;
Zhang, Deyi
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/03/01
Antibiotics
Cuprous oxide nanoparticles
Drug resistant
Nanocomposites
Polyaniline
Discovery and Development of a Potent, Selective, and Orally Bioavailable CHK1 Inhibitor Candidate: 5-((4-((3-Amino-3-methylbutyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)picolinonitrile
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15069-15090
作者:
Jin, Tingting
;
Xu, Lei
;
Wang, Peipei
;
Hu, Xiaobei
;
Zhang, Runyuan
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/01/04
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
Metal-drug nanoparticles-mediated osteolytic microenvironment regulation for enhanced radiotherapy of orthotopic osteosarcoma
期刊论文
CHEMICAL ENGINEERING JOURNAL, 2021, 卷号: 417, 页码: 11
作者:
Geng, Huan
;
Zhou, Mengxue
;
Li, Bin
;
Liu, Liang
;
Yang, Xu
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/08/17
Metal-drug nanoparticles
Orthotopic osteosarcoma
Osteolytic microenvironment
Zoledronate
Radiotherapy
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3K delta inhibitor idelalisib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhou, Xiao-ru
;
Li, Xiao
;
Liao, Li-ping
;
Han, Jie
;
Huang, Jing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/06/11
mantle cell lymphoma
idelalisib
drug resistance
P300
CBP
synergistic drug action
PI3Kδ
epigenetics
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