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Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文
FRONTIERS IN CHEMISTRY, 2022, 卷号: 10
作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng
收藏  |  浏览/下载:19/0  |  提交时间:2022/12/23
Identification of SARS-CoV-2 entry inhibitors among already approved drugs 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:  Yang, Li;  Pei, Rong-juan;  Li, Heng;  Ma, Xin-na;  Zhou, Yu
收藏  |  浏览/下载:42/0  |  提交时间:2020/12/24
GPR91, a critical signaling mechanism in modulating pathophysiologic processes in chronic illnesses 期刊论文
FASEB JOURNAL, 2020, 页码: 15
作者:  Li, Xinyi;  Xie, Li;  Qu, Xiangli;  Zhao, Bangyi;  Fu, Wei
收藏  |  浏览/下载:26/0  |  提交时间:2020/12/24
Molecular dynamics simulation revealed the intrinsic conformational change of cellular inhibitor of apoptosis protein-1 期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020, 卷号: 38, 期号: 4, 页码: 975-984
作者:  Xu, Heng;  Tang, Zhengkuan;  Zuo, Yu;  Xiong, Fengmin;  Chen, Kaixian
收藏  |  浏览/下载:40/0  |  提交时间:2020/07/01
3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 18, 页码: 8136-8154
作者:  Baqi, Younis;  Pillaiyar, Thanigaimalai;  Abdelrahman, Aliaa;  Kaufmann, Olesja;  Aishaibani, Samer
收藏  |  浏览/下载:105/0  |  提交时间:2019/01/08
Structural basis of ligand binding modes at the neuropeptide Y Y-1 receptor 期刊论文
NATURE, 2018, 卷号: 556, 期号: 7702, 页码: 520-+
作者:  Yang, Zhenlin;  Han, Shuo;  Keller, Max;  Kaiser, Anette;  Bender, Brian J.
收藏  |  浏览/下载:38/0  |  提交时间:2019/01/08
The chemical diversity and structure-based evolution of non-peptide CXCR4 antagonists with diverse therapeutic potential 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 149, 页码: 148-169
作者:  Peng, Dian;  Cao, Bin;  Zhou, Ying-Jun;  Long, Ya-Qiu
收藏  |  浏览/下载:38/0  |  提交时间:2019/01/08
Design, synthesis and pharmacological evaluation of new acyl sulfonamides as potent and selective Bcl-2 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 2, 页码: 443-454
作者:  Liu, Xiaohua;  Zhang, Yu;  Huang, Wenjing;  Tan, Wenfu;  Zhang, Ao
收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
A Fusion Protein of the p53 Transaction Domain and the p53-Binding Domain of the Oncoprotein MdmX as an Efficient System for High-Throughput Screening of MdmX Inhibitors 期刊论文
BIOCHEMISTRY, 2017, 卷号: 56, 期号: 25, 页码: 3273-3282
作者:  Qin, Lingyun;  Zhou, Jingjing;  Su, Zhengding;  Liu, Huili;  Huang, Yongqi
收藏  |  浏览/下载:32/0  |  提交时间:2017/12/06
Discovery of non-peptide small molecular CXCR4 antagonists as anti-HIV agents: Recent advances and future opportunities 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 114, 页码: 65-78
作者:  Zhang, Heng;  Kang, Dongwei;  Huang, Boshi;  Liu, Na;  Zhao, Fabao
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/16


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