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科研机构
上海药物研究所 [12]
复旦大学上海医学院 [3]
内容类型
期刊论文 [15]
发表日期
2020 [2]
2019 [1]
2018 [2]
2017 [2]
2016 [1]
2015 [4]
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Clinical application of pyrrole-hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans
期刊论文
ARCHIVES OF TOXICOLOGY, 2020, 页码: 7
作者:
Ma, Jiang
;
Zhang, Wei
;
He, Yisheng
;
Zhu, Lin
;
Zhang, Chunyuan
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/12/24
Pyrrolizidine alkaloids
Liver injury
Diagnostic biomarkers
Pyrrole-hemoglobin adducts
Pyrrole-plasma protein adducts
Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Zhu, Lin
;
Zhang, Chun-yuan
;
Li, Dong-ping
;
Chen, Hu-biao
;
Ma, Jiang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/12/24
herb-induced liver injury
hepatic sinusoidal obstruction syndrome
pyrrolizidine alkaloids
Tu-San-Qi
Gynura japonica
Pyrrole-Hemoglobin Adducts, a More Feasible Potential Biomarker of Pyrrolizidine Alkaloid Exposure
期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 6, 页码: 1027-1039
作者:
Ma, Jiang
;
Ruan, Jianqing
;
Chen, Xinmeng
;
Li, Dongping
;
Yao, Sheng
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/07/01
The role of formation of pyrrole-ATP synthase subunit beta adduct in pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
ARCHIVES OF TOXICOLOGY, 2018, 卷号: 92, 期号: 11, 页码: 3403-3414
作者:
Lu, Yao
;
Ma, Jiang
;
Song, Zijing
;
Ye, Yang
;
Fu, Peter P.
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloid
Retrorsine
ATP5B
Mitochondrial damage
Pyrrole-protein adduct
Pyrrole-protein adducts - A biomarker of pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
JOURNAL OF FOOD AND DRUG ANALYSIS, 2018, 卷号: 26, 期号: 3, 页码: 965-972
作者:
Ma, Jiang
;
Xia, Qingsu
;
Fu, Peter P.
;
Lin, Ge
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloids
Pyrrole-protein adducts
Covalent binding
Target protein
Mechanism-based biomarker
Clinical diagnosis
First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans
期刊论文
ARCHIVES OF TOXICOLOGY, 2017, 卷号: 91, 期号: 12, 页码: 3913-3925
作者:
Yang, Mengbi
;
Ruan, Jianqing
;
Gao, Hong
;
Li, Na
;
Ma, Jiang
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
Pyrrolizidine alkaloid N-oxide
Pyrrolizidine alkaloid
Hepatic sinusoidal obstruction syndrome
Pyrrole-protein adduct
Biotransformation
Toxicokinetic
Immunoassay approach for diagnosis of exposure to pyrrolizidine alkaloids
期刊论文
Journal of Environmental Science and Health - Part C Environmental Carcinogenesis and Ecotoxicology Reviews, 2017, 卷号: 35, 期号: 3, 页码: 127-139
作者:
Li, Na
;
Zhang, Fan
;
Lian, Wei
;
Wang, Huali
;
Zheng, Jiang
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/01/08
Cytotoxicity of pyrrolizidine alkaloid in human hepatic parenchymal and sinusoidal endothelial cells: Firm evidence for the reactive metabolites mediated pyrrolizidine alkaloid-induced hepatotoxicity
期刊论文
Chemico-biological interactions, 2016, 卷号: 243, 页码: 119-26
作者:
Yang, Mengbi
;
Ruan, Jianqing
;
Fu, Peter P
;
Lin, Ge
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
Blood Pyrrole-Protein Adducts-A Biomarker of Pyrrolizidine Alkaloid-Induced Liver Injury in Humans
期刊论文
JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS, 2015, 卷号: 33, 期号: 4, 页码: 404-421
作者:
Ruan, Jianqing
;
Gao, Hong
;
Li, Na
;
Xue, Junyi
;
Chen, Jie
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
hepatic sinusoidal obstruction syndrome
hepatotoxicity
pyrrolizidine alkaloids
pyrrole-protein adducts
Blood pyrrole-protein adducts as a diagnostic and prognostic index in pyrrolizidine alkaloid-hepatic sinusoidal obstruction syndrome
期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2015, 卷号: 9
作者:
Gao, Hong
;
Ruan, Jianqing Q.
;
Chen, Jie
;
Li, Na
;
Ke, Changqiang Q.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/19
drug-induced liver injury
herb
blood protein adducts
prognostic marker
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