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CORC

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Discovery and structure - activity relationship exploration of pyrazolo [1,5-a]pyrimidine derivatives as potent FLT3-ITD inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 48, 页码: 13
作者:  Chen, Yun;  Bai, Gang;  Li, Yan;  Ning, Yi;  Cao, Sufen
收藏  |  浏览/下载：32/0  |  提交时间：2021/12/01
Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors 期刊论文
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:  Xu, Jianghong;  Hu, Yuanyuan;  Liu, Xiaoqi;  Gao, Anhui;  Gao, Lixin
收藏  |  浏览/下载：37/0  |  提交时间：2021/12/01
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:  Wu, Xiaowei;  Dai, Mengdi;  Cui, Rongrong;  Wang, Yulan;  Li, Chunpu
收藏  |  浏览/下载：47/0  |  提交时间：2021/05/24
Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 16, 页码: 7473-7488
作者:  Wang, Yulan;  Dai, Yang;  Wu, Xiaowei;  Li, Fei;  Liu, Bo
收藏  |  浏览/下载：18/0  |  提交时间：2020/07/01
Synthesis and biological evaluation of novel 1-substituted 3-(3-phenoxyprop-1-yn-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amines as potent Bruton's tyrosine kinase (BTK) inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2
作者:  Zheng, Nan;  Hao, Qun;  Lin, Kuaile;  Pan, Jing;  Li, Yingxia
收藏  |  浏览/下载：14/0  |  提交时间：2019/12/05
3,5-Diaryl-1H-pyrazolo[3,4-b]pyridines as potent tubulin polymerization inhibitors: Rational design, synthesis and biological evaluation 期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: Vol.168, 页码: 426-435
作者:  Min'an Zhai;  Shiyuan Liu;  Meiqi Gao;  Long Wang;  Jun Sun
收藏  |  浏览/下载：30/0  |  提交时间：2019/12/13
Synthesis and structure-activity relationships of pyrazolo-[3,4-b]pyridine derivatives as adenosine 5'-monophosphate-activated protein kinase activators 期刊论文
ARCHIV DER PHARMAZIE, 2019, 卷号: 352, 期号: 8
作者:  Zheng, Bifeng;  Peng, Yajun;  Wu, Weihong;  Ma, Junlong;  Zhang, Yuzhao
收藏  |  浏览/下载：12/0  |  提交时间：2019/12/11
Alcohol Participates in the Synthesis of Functionalized Coumarin-Fused Pyrazolo[3,4-b]Pyridine from a One-Pot Three-Component Reaction 期刊论文
2019, 卷号: 24, 期号: 15
作者:  Lin Wei;  Zhuang Cangwei;  Hu Xiuxiu;  Zhang Juanjuan;  Wang Juxian
收藏  |  浏览/下载：12/0  |  提交时间：2020/01/03
Synthesis and biological evaluation of pyrazolo[3,4-b]pyridine-3-yl pyrimidine derivatives as sGC stimulators for the treatment of pulmonary hypertension 期刊论文
2019, 卷号: 173, 页码: 107-116
作者:  Li, Liang;  Zhang, Wenpeng;  Lin, Feng;  Lu, Xinqiang;  Chen, Wei
收藏  |  浏览/下载：14/0  |  提交时间：2020/01/03
Discovery of novel selective Janus kinase 2 (JAK2) inhibitors bearing a 1H-pyrazolo[3,4-d]pyrimidin-4-amino scaffold 期刊论文
2019, 卷号: 27, 期号: 8, 页码: 1562-1576
作者:  Yin, Yuan;  Chen, Cheng-Juan;  Yu, Ru-Nan;  Shu, Lei;  Zhang, Tian-Tai
收藏  |  浏览/下载：3/0  |  提交时间：2020/01/03

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