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Construction of a ceRNA Network and Comprehensive Analysis of lncRNA in Hepatocellular Carcinoma
期刊论文
GENES, 2022, 卷号: 13
作者:
Wang, Lin
;
Zhao, Jun
;
Zhu, Cancan
;
Yang, Ke
;
Zhu, Ling
收藏
  |  
浏览/下载:281/0
  |  
提交时间:2022/12/23
hepatocellular carcinoma
competing endogenous RNA
mRNA-miRNA-lncRNA
bioinformatics analysis
GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13
作者:
Zhang, Qing
;
Chen, Lin-hai
;
Yang, Hui
;
Fang, You-chen
;
Wang, Si-wei
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/01/18
GPR84
medium chain fatty acid receptor
GPCR
inflammatory bowel diseases
ulcerative colitis
NLRP3 inflammasome
macrophages
Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 224, 页码: 14
作者:
He, Yu-Long
;
Chen, Meng-Ting
;
Wang, Ting
;
Zhang, Ming-Ming
;
Li, Ying-Xia
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2021/11/04
Type 2 diabetes mellitus
Dual FABP4/5 inhibitors
Anti-lipolytic and anti-inflammatory effects
Metabolic stability
Anti-diabetic activities
Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation
期刊论文
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:
Li, Heng
;
Zhang, Xianglei
;
Xiang, Caigui
;
Feng, Chunlan
;
Fan, Chen
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  |  
浏览/下载:87/0
  |  
提交时间:2021/11/04
PDE4
Arctigenin
Psoriasis
Inflammation
Drug target inference by mining transcriptional data using a novel graph convolutional network framework
期刊论文
PROTEIN & CELL, 2021, 页码: 21
作者:
Zhong, Feisheng
;
Wu, Xiaolong
;
Yang, Ruirui
;
Li, Xutong
;
Wang, Dingyan
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/12/01
drug target inference
transcriptomics
deep learning
experimental verification
Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:
Bao, Weilian
;
Liu, Xiaohong
;
You, Yan
;
Hou, Hui
;
Wang, Xu
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  |  
浏览/下载:58/0
  |  
提交时间:2021/11/16
SNX10
IBD
Macrophage
PIKfyve
TBK1
PPI inhibitor
Molecular Dynamics Simulations Reveal the Modulated Mechanism of STING Conformation
期刊论文
INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES, 2021, 页码: 15
作者:
Chen, Li
;
Zhao, Shuang
;
Zhu, Yanyan
;
Liu, Yongsheng
;
Li, Huiyu
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  |  
浏览/下载:26/0
  |  
提交时间:2021/08/17
STING
Small molecule
Binding site
Modulated mechanism
Molecular dynamics simulation
pi-pi stacking interaction
SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Xi
;
Duan, Yu-ting
;
Wang, Yi
;
Zhao, Xing-dong
;
Sun, Yi-ming
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  |  
浏览/下载:37/0
  |  
提交时间:2021/05/24
PI3Kδ
PI3K
AKT
mTOR
diffuse large B-cell lymphoma
resistance
combination therapy
Diversified strategy for the synthesis of DNA-encoded oxindole libraries
期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 12, 期号: 8, 页码: 2841-2847
作者:
Wang, Xuan
;
Liu, Jiaxiang
;
Yan, Ziqin
;
Liu, Xiaohong
;
Liu, Sixiu
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
NOD-like receptors in autoimmune diseases
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 15
作者:
Chen, Li
;
Cao, Shi-qi
;
Lin, Ze-min
;
He, Shi-jun
;
Zuo, Jian-ping
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2021/05/24
pattern recognition receptors
NOD-like receptors
autoimmune diseases
inflammasomes
inhibitors
botanicals
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