CORC

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CORC

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A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects 期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15, 页码: 2947-2959
作者:  Qian, Hongjie;  Chen, Qian;  Lang, Liyu;  Zou, Yang;  Pu, Huahua
收藏  |  浏览/下载：34/0  |  提交时间：2021/08/17
Characterization of TPN171 metabolism in humans via ultra-performance liquid chromatography/quadrupole time-of-flight Checir for mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2019, 卷号: 172, 页码: 302-310
作者:  Pan, Lulu;  Guo, Shuang;  Chen, Xiaoyan;  Jiang, Xiangrui;  Shen, Jingshan
收藏  |  浏览/下载：53/0  |  提交时间：2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Zhen;  Jiang, Xiangrui;  Zhang, Xianglei;  Tian, Guanghui;  Yang, Rulei
收藏  |  浏览/下载：39/0  |  提交时间：2020/07/01
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 10, 页码: 4979-4990
作者:  Wang, Z (Wang, Zhen)[ 1 ];  Jiang, XR (Jiang, Xiangrui)[ 1 ];  Zhang, XL (Zhang, Xianglei)[ 1,2 ];  Tian, GH (Tian, Guanghui)[ 3 ];  Yang, RL (Yang, Rulei)[ 3 ]
收藏  |  浏览/下载：137/0  |  提交时间：2019/06/28
Effect of phosphodiesterase type 5 inhibitors on prostate cancer risk and biochemical recurrence after prostate cancer treatment: A systematic review and meta-analysis 期刊论文
ANDROLOGIA, 2019, 卷号: 51, 期号: 2
作者:  Hong, Yang;  Wu, Yougen;  Qu, Xiaofeng;  Wang, Yang;  Xia, Ju
收藏  |  浏览/下载：23/0  |  提交时间：2019/12/05
The effect of CPAP and PDE5i on erectile function in men with obstructive sleep apnea and erectile dysfunction: A systematic review and meta-analysis 期刊论文
Sleep Medicine Reviews, 2019, 卷号: 48
作者:  Li Z.;  Fang Z.;  Xing N.;  Zhu S.;  Fan Y.
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/11
Are phosphodiesterase type 5 inhibitors associated with increased risk of melanoma? 期刊论文
Medicine (Baltimore), 2018, 卷号: Vol.97 No.3, 页码: e9601
作者:  Shijian Feng;  Liang Zhou;  Qinyu Liu;  Qing He;  Banghua Liao
收藏  |  浏览/下载：5/0  |  提交时间：2019/02/25
Association between phosphodiesterase type 5 inhibitors use and risk of melanoma: a meta-analysis 期刊论文
2018, 卷号: 65, 期号: 2, 页码: 216
作者:  Deng, T.[1,2,3];  Duan, X.[1,2,3];  Liu, B.[4];  Lan, Y.[1,2,3];  Cai, C.[1,2,3]
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/17
Characterization of TPN729 metabolites in humans using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry 期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2016, 卷号: 117, 页码: 217-226
作者:  Zhu, Yunting;  Li, Liang;  Deng, Pan;  Chen, Xiaoyan;  Zhong, Dafang
收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08
Systematic review and meta-analysis of phosphodiesterase type 5 inhibitors for the treatment of female sexual dysfunction 期刊论文
International Journal of Gynecology & Obstetrics, 2016, 卷号: Vol.133 No.2, 页码: 139-145
作者:  Liang Gao;  Lu Yang;  Shengqiang Qian;  Tao Li;  Ping Han
收藏  |  浏览/下载：7/0  |  提交时间：2019/02/25

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