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上海药物研究所 [5]
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期刊论文 [18]
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Challenges and stepwise fit-for-purpose optimization for bioanalyses of remdesivir metabolites nucleotide monophosphate and triphosphate in mouse tissues using LC-MS/MS
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2021, 卷号: 194, 页码: 10
作者:
Hu, Wenjuan
;
Chang, Lu
;
Ke, Changqiang
;
Xie, Yuanchao
;
Shen, Jingshan
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/05/24
Remdesivir
Nucleotide monophosphate
Nucleotide triphosphate
Stability
Recovery
LC-MS/MS
Effects on larval metamorphosis in the mussel Mytilus coruscus of compounds that act on downstream effectors of G-protein-coupled receptors
期刊论文
JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM, 2018, 卷号: 98, 期号: 2, 页码: 333-339
作者:
Liang, Xiao
;
Chen, Yu-Ru
;
Gao, Wei
;
Guo, Xing-Pan
;
Ding, De-Wen
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/08/19
Mytilus coruscus
larval metamorphosis
pharmacological compounds
G protein-coupled receptor
Effects on larval metamorphosis in the mussel Mytilus coruscus of compounds that act on downstream effectors of G-protein-coupled receptors
期刊论文
JOURNAL OF THE MARINE BIOLOGICAL ASSOCIATION OF THE UNITED KINGDOM, 2018, 卷号: 98, 期号: 2, 页码: 333-339
作者:
Liang, Xiao
;
Chen, Yu-Ru
;
Gao, Wei
;
Guo, Xing-Pan
;
Ding, De-Wen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2018/12/07
Mytilus coruscus
larval metamorphosis
pharmacological compounds
G protein-coupled receptor
Varying 10-year off-treatment responses to nucleos(t)ide analogues in patients with chronic hepatitis B according to their pretreatment hepatitis B e antigen status
期刊论文
JOURNAL OF DIGESTIVE DISEASES, 2018, 卷号: 19, 期号: 9, 页码: 561-571
作者:
Liu, Feng
;
Liu, Zhi Rong
;
Li, Tao
;
Liu, You De
;
Zhang, Meng
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/11
chronic hepatitis B
hepatitis B e antigens
hepatitis B surface
antigens
nucleoside analogue
nucleotide analogue
recurrence
Crystal structures of the kinase domain of PpkA, a key regulatory component of T6SS, reveal a general inhibitory mechanism
期刊论文
BIOCHEMICAL JOURNAL, 2018, 卷号: 475, 期号: -, 页码: 2209-2224
作者:
Li, PP
;
Xu, DQ
;
Ma, TQ
;
Wang, DY
;
Li, WD
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/17
VI SECRETION SYSTEM
DEPENDENT PROTEIN-KINASE
GRAM-NEGATIVE BACTERIA
MYCOBACTERIUM-TUBERCULOSIS
SERINE/THREONINE KINASE
CATALYTIC DOMAIN
CONFORMATIONAL PLASTICITY
PSEUDOMONAS-AERUGINOSA
ACTIVATION MECHANISM
EDWARDSIELLA-TARDA
The enrichment of HBV immune-escape mutations during nucleoside/nucleotide analogue therapy
期刊论文
ANTIVIRAL THERAPY, 2017, 卷号: 22, 期号: 8
作者:
Shan, Menglin
;
Shen, Zhen
;
Sun, Hua
;
Zheng, Jianghua
;
Zhang, Min
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor alpha and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 17, 页码: 7856-7876
作者:
Golani, Lalit K.
;
Wallace-Povirk, Adrianne
;
Deis, Siobhan M.
;
Wong, Jennifer
;
Ke, Jiyuan
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Meta-analysis of the efficacy and safety of nucleotide/nucleoside analog monotherapy for hepatitis B virus-associated glomerulonephritis
期刊论文
CLINICAL NEPHROLOGY, 2016, 卷号: 85, 期号: 1
作者:
Wang, Wan-ning
;
Xu, Zhong-gao
;
Sun, Tao
;
Ma, Fu-zhe
;
Wu, Mei-yan
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
meta-analysis
hepatitis B virus
glomerulonephritis
nucleotide/nucleoside analogue
The Crystal Structure of the PB2 Cap-binding Domain of Influenza B Virus Reveals a Novel Cap Recognition Mechanism
期刊论文
the journal of biological chemistry, 2015
Liu Yong
;
Yang Yongfeng
;
Fan Jialin
;
He Ruina
;
Luo Ming
;
Zheng Xiaofeng
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/13
Cap Binding,Crystal Structure,GDP,Influenza Virus,Nucleoside/Nucleotide Analogue,PB2,Protein Structure,RNA Polymerase,m7GDP
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