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Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64
作者:  Fu, Weitao;  Zhang, Minkui;  Liao, Jianing;  Tang, Qing;  Lei, Yixuan
收藏  |  浏览/下载:53/0  |  提交时间:2022/03/21
GPR52 Antagonist Reduces Huntingtin Levels and Ameliorates Huntington's Disease-Related Phenotypes 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 2, 页码: 941-957
作者:  Wang, Congcong;  Zhang, Yu-Fang;  Guo, Shimeng;  Zhao, Quan;  Zeng, Yanping
收藏  |  浏览/下载:21/0  |  提交时间:2021/05/24
Sanguinarine is an agonist of TRPA1 channel 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021, 卷号: 534, 页码: 226-232
作者:  Chi, Hao;  Zhang, Xian;  Chen, Xueqin;  Fang, Sui;  Ding, Qiang
收藏  |  浏览/下载:17/0  |  提交时间:2021/05/24
Discovery of 3-((dimethylamino)methyl)-4-hydroxy-4-(3-methoxypheny1)-N-phenylpiperidine-1-carboxamide as novel potent analgesic 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 189, 页码: 14
作者:  Huang, Huoming;  Wang, Wenli;  Xu, Xuejun;  Zhu, Chen;  Wang, Yujun
收藏  |  浏览/下载:34/0  |  提交时间:2020/07/01
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
收藏  |  浏览/下载:92/0  |  提交时间:2020/07/01
Discovery of Novel Androgen Receptor Ligands by Structure-based Virtual Screening and Bioassays 期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 16, 期号: 6, 页码: 416-427
作者:  Hou, Tingjun;  Li, Dan;  Chang, Shan;  Xu, Lei;  Sun, Huiyong
收藏  |  浏览/下载:263/0  |  提交时间:2019/06/24
Enantioselective determination of ketamine in dog plasma by chiral liquid chromatography-tandem mass spectrometry 期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2019, 卷号: 33, 期号: 9, 页码: 8
作者:  Li, Ranran;  Zhong, Kan;  Jiang, Jinfang;  Zhan, Yuan;  Chen, Xiaoyan
收藏  |  浏览/下载:23/0  |  提交时间:2020/07/01
Carboxylesterase 2 and Intestine Transporters Contribute to the Low Bioavailability of Allisartan, a Prodrug of Exp3174 for Hypertension Treatment in Humans 期刊论文
DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 8, 页码: 843-853
作者:  Li, Xiuli;  Sun, Jingchao;  Guo, Zitao;  Zhong, Dafang;  Chen, Xiaoyan
收藏  |  浏览/下载:21/0  |  提交时间:2020/07/01
A meta-analysis of naldemedine for the treatment of opioid-induced constipation 期刊论文
EXPERT REVIEW OF CLINICAL PHARMACOLOGY, 2019, 卷号: 12, 期号: 2
作者:  Song, Xuesong;  Qu, Xiaoyu;  Dong, Naifu;  Teng, Shiyong;  Wang, Dunwei
收藏  |  浏览/下载:23/0  |  提交时间:2019/12/05
Structure-Based Design of 1-Heteroary1-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 21, 页码: 9621-9636
作者:  Peng, Panfeng;  Chen, Huan;  Zhu, Ya;  Wang, Zhilong;  Li, Jian
收藏  |  浏览/下载:56/0  |  提交时间:2019/01/08


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