×
验证码:
换一张
忘记密码?
记住我
CORC
首页
科研机构
检索
知识图谱
申请加入
托管服务
登录
注册
在结果中检索
科研机构
厦门大学 [2]
上海药物研究所 [2]
南华大学 [1]
北京大学 [1]
四川大学 [1]
中南大学 [1]
更多...
内容类型
期刊论文 [10]
发表日期
2018 [1]
2016 [2]
2015 [2]
2014 [1]
2013 [4]
×
知识图谱
CORC
开始提交
已提交作品
待认领作品
已认领作品
未提交全文
收藏管理
QQ客服
官方微博
反馈留言
浏览/检索结果:
共10条,第1-10条
帮助
已选(
0
)
清除
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
作者升序
作者降序
题名升序
题名降序
发表日期升序
发表日期降序
提交时间升序
提交时间降序
Dihydrocelastrol exerts potent antitumor activity in mantle cell lymphoma cells via dual inhibition of mTORC1 and mTORC2
期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 卷号: 53, 期号: 2, 页码: 823-834
作者:
Xie, Yongsheng
;
Li, Bo
;
Bu, Wenxuan
;
Gao, Lu
;
Zhang, Yong
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2019/01/08
mantle cell lymphoma
dihydrocelastrol
apoptosis
cell cycle
mTORC1
mTORC2
Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer
期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 67071-67086
作者:
Qian, Jianchang
;
Chen, Yaqing
;
Meng, Tao
;
Ma, Lanping
;
Meng, Lanfang
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
mTOR kinase inhibitor
mTORC2
apoptosis
lipid metabolism
Bridges between mitochondrial oxidative stress, ER stress and mTOR signaling in pancreatic β cells
期刊论文
Cellular Signalling, 2016, 卷号: 28, 期号: 8, 页码: 1099-1104
作者:
Wang, Jing
;
Yang, Xin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/12/03
4E-BP1
4E binding protein
AMPK
AMP-activated protein kinase
ATF6
activating transcription factor 6
ATP
adenosine triphosphate
DEPTOR
DEP domain containing mTOR-interacting protein
CI
complexes I
CII
complex II
CIII
complex III
CIV
complex IV
CV
complex V
eIF2α
Eukaryotic Initiation Factor 2α
ER
Endoplasmic Reticulum
ERAD
ER-associated degradation
ERO1α
ER oxidoreductase 1 α
FoxO1
Forkhead box O1
GβL
G Protein β Subunit Like Protein
GRP78
78 kDa glucose-regulated protein precursor
GSIS
glucose-stimulated insulin secretion
IRE1
Inositol-requiring enzyme 1
IRS1
Insulin receptor substrate 1
IRS2
Insulin receptor substrate 2
mLST8
mammalian lethal with sec-13 protein 8
mSin1
the mammalian stress-activated MAP kinase-interaction protein 1
mtDNA
mitochondrial deoxyribonucleic acid
mTOR
mammalian TOR
mTORC1
mTOR complex 1
mTORC2
mTOR complex 2
NADPH oxidase
Nicotinamide adenine dinucleotide phosphate-oxidase
NOS
nitric oxide synthase
O2–·
superoxide anion
H2O2
hydrogen peroxide
OH·
hydroxyl radical
3O2
triplet-state molecular oxygen
OXPHOS
oxidative phosphorylation
CAT
catalase
GPx
glutathioneperoxidase
PERK
Protein kinase R-like endoplasmic reticulum kinase
PDI
ER protein disulfide isomerases
PI3K
the phosphoinositide3-kinase
PRAS40
40-kDa proline-rich Akt substrate
PRAS40
the 40-kDa proline-rich Akt substrate
PROTOR
the protein observed with RICTOR
RAPTOR
regulatory-associated protein of mTOR
RICTOR
The rapamycin-insensitive companion of mTOR
REDD1
DNA damage response 1
RNS
reactive nitrogen species
ROS
reactive oxygen species
RNS
reactive nitrogen species
S6K
S6 kinase
SOD
superoxidedismutase
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TOR
the target of rapamycin
TSC2
Tuberous sclerosis 2
UPR
unfolded protein response
Mitochondrial oxidative stress
ER stress
mTOR
Pancreatic β cells
Insulin upregulates the expression of epithelial sodium channel in vitro and in a mouse model of acute lung injury: Role of mTORC2/SGK1 pathway
期刊论文
Experimental Cell Research, 2015, 卷号: Vol.331 No.1, 页码: 164-175
作者:
Jing He
;
Di Qi
;
Dao-xin Wang
;
Wang Deng
;
Yuan Ye
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/02/25
Acute lung injury
Alveolar fluid clearance
Epithelial sodium channel
Mammalian target of rapamycin complex
Insulin
Serum and glucocorticoid-induced kinase-1
The synergistic inhibition of breast cancer proliferation by combined treatment with 4EGI-1 and MK2206
期刊论文
2015, 卷号: 14, 期号: 2, 页码: 232-242
作者:
Wang, Hongtao
;
Huang, Fang
;
Wang, Jian
;
Wang, Peng
;
Lv, Wenjie
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/13
AKT
eIF4E
eIF4F complex
cap-dependent translation
4EBP1
4EGI-1
mTORC1
mTORC2
eIF4E
eukaryotic translation initiation factor 4E
4EBP1
eIF4E-binding protein 1
p70S6K
ribosomal p70 S6 kinase
mTORC1
mammalian target of rapamycin complex 1
mTORC2 mammalian target of rapamycin complex 2
PI3K
phosphatidylinositol 3-kinase
ER stress
endoplasmic reticulum stress
SIRT1 in cardiovascular aging
期刊论文
Clinica Chimica Acta, 2014, 卷号: 437, 页码: 106-114
作者:
Luo, Xin-Yuan
;
Qu, Shun-Lin
;
Tang, Zhi-Han
;
Zhang, Yuan
;
Liu, Mi-Hua
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/27
CVD
cardiovascular disease
SIRT1
sirtuin1
LV
left ventricular
Sir2
silent information regulator 2
rDNA
recombinant DNA
PI3K
phosphoinositide 3-hydroxykinase
NF-κB
nuclear factor kappa B
FOXOs
forkhead box O transcription factors
ROS
reactive oxygen species
mTOR
mammalian (or mechanistic) target of rapamycin
H2O2
hydrogen peroxide
NO
nitric oxide
GADD45
DNA damage-inducible protein 45
MnSOD
manganese superoxide dismutase
H2S
hydrogen sulfide
HUVECs
human umbilical vein endothelial cells
eNOS
endothelial nitric oxide synthase
miR
microRNA
CR
caloric restriction
AP-1
activator protein 1
STACs
small molecule activators of SIRT1
mTORC1
mTOR complex 1
mTORC2
mTOR complex 2
LC
light chain
IGF
insulin-like growth factor
Atgs
autophagy-related genes
SIRT1
Cardiovascular aging
Oxidative stress
Inflammation
Autophagy
Anti-aging strategies
IKK interacts with rictor and regulates mTORC2
期刊论文
CELLULAR SIGNALLING, 2013, 卷号: 25, 期号: 11
作者:
Xu, Yuanfei
;
Lai, Eryong
;
Liu, Jun
;
Lin, Jun
;
Yang, Cuilan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/04
The IKB kinase
Rictor
The mammalian target of rapamycin complex 2
Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway
期刊论文
genes development, 2013
Lee, Kyu-Sun
;
Wu, Zhihao
;
Song, Yan
;
Mitra, Siddhartha S.
;
Feroze, Abdullah H.
;
Cheshier, Samuel H.
;
Lu, Bingwei
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/16
Notch
PINK1
mTORC2/AKT signaling
mitochondria
neural stem cells
cancer stem cells
PARKINSONS-DISEASE
QUALITY-CONTROL
SELF-RENEWAL
DROSOPHILA
CANCER
DIVISION
GROWTH
DIFFERENTIATION
MUTATIONS
INTERACTS
The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling
期刊论文
http://dx.doi.org/10.1002/emmm.201201369, 2013
Wang, Rong-Hao
;
He, Jian-Ping
;
Su, Mao-Long
;
Luo, Jie
;
Xu, Ming
;
Du, Xiao-Dan
;
Chen, Hang-Zi
;
Wang, Wei-Jia
;
Wang, Yuan
;
Zhang, Nan
;
Zhao, Bi-Xing
;
Zhao, Wen-Xiu
;
Shan, Zhong-Gui
;
Han, Jiahuai
;
Chang,
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2013/12/12
angiotensin II
cardiac hypertrophy
mammalian target of rapamycin
orphan receptor TR3
tuberous sclerosis complex
The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling
期刊论文
http://dx.doi.org/10.1002/emmm.201201369, 2013
Wang, Rong-Hao
;
He, Jian-Ping
;
Su, Mao-Long
;
Luo, Jie
;
Xu, Ming
;
Du, Xiao-Dan
;
Chen, Hang-Zi
;
Wang, Wei-Jia
;
Wang, Yuan
;
Zhang, Nan
;
Zhao, Bi-Xing
;
Zhao, Wen-Xiu
;
Shan, Zhong-Gui
;
Han, Jiahuai
;
Chang,Chawnshang
;
Wu,Qiao
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2013/12/12
angiotensin II
cardiac hypertrophy
mammalian target of rapamycin
orphan receptor TR3
tuberous sclerosis complex
©版权所有 ©2017 CSpace - Powered by
CSpace