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Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 10, 页码: 3206-3219
作者:  Lu, Tian;  Li, Yong;  Lu, Wenchao;  Spitters, Twgm;  Fang, Xueyu
收藏  |  浏览/下载:39/0  |  提交时间:2021/12/01
Identification of methyl (5-(6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinopyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-(trifluoromethyl)pyridin-2-yl)carbamate (CYH33) as an orally bioavailable, highly potent, PI3K alpha inhibitor for the treatment of advanced solid tumors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 10
作者:  Xiang, Hao-Yue;  Wang, Xiang;  Chen, Yan-Hong;  Zhang, Xi;  Tan, Cun
收藏  |  浏览/下载:33/0  |  提交时间:2021/05/24
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao
收藏  |  浏览/下载:17/0  |  提交时间:2020/03/18
A selenium- containing selective histone deacetylase 6 inhibitor for targeted in vivo breast tumor imaging and therapy 期刊论文
JOURNAL OF MATERIALS CHEMISTRY B, 2019, 卷号: 7, 期号: 22, 页码: 3528-3536
作者:  Tang, Chu;  Du, Yang;  Liang, Qian;  Cheng, Zhen;  Tian, Jie
收藏  |  浏览/下载:56/0  |  提交时间:2019/09/30
Design, Synthesis, and Biological Evaluation of 2,4-Imidazolinedione Derivatives as HDAC6 Isoform-Selective Inhibitors 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 10, 期号: 8, 页码: 1122-1127
作者:  Liang, Tao;  Hou, Xuben;  Zhou, Yi;  Yang, Xinying;  Fang, Hao
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/11
Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia
收藏  |  浏览/下载:84/0  |  提交时间:2019/01/08
Molecular cloning, expression pattern of follistatin gene and association analysis with growth traits in bighead carp (Hypophthalmichthys nobilis) 期刊论文
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 2018, 卷号: 218, 期号: 1, 页码: 44-53
作者:  Pang, Meixia;  Tong, Jingou;  Yu, Xiaomu;  Fu, Beide;  Zhou, Ying
收藏  |  浏览/下载:29/0  |  提交时间:2019/07/03
A RECK-WNT7 Receptor-Ligand Interaction Enables Isoform-Specific Regulation of Wnt Bioavailability 期刊论文
CELL REPORTS, 2018
作者:  Kuo, Calvin J.;  Garcia, K. Christopher;  Noda, Makoto;  Essler, Markus;  Miao, Yi
收藏  |  浏览/下载:39/0  |  提交时间:2019/01/31
Arenobufagin is a novel isoform-specific probe for sensing human sulfotransferase 2A1 期刊论文
药学学报, 2018, 卷号: 8, 期号: 5
作者:  Tian Xiangge;  Wang Chao;  Dong Peipei;  An Yue;  Zhao Xinyu
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/05
Arenobufagin is a novel isoform-specific probe for sensing human sulfotransferase 2A1 期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 5
作者:  Tian, Xiangge;  Wang, Chao;  Dong, Peipei;  An, Yue;  Zhao, Xinyu
收藏  |  浏览/下载:9/0  |  提交时间:2019/12/05


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