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上海药物研究所 [26]
厦门大学 [17]
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复旦大学上海医学院 [6]
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Drug-resistant HER2-positive breast cancer: Molecular mechanisms and overcoming strategies
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Wu, Xiaofan
;
Yang, Hongjian
;
Yu, Xingfei
;
Qin, Jiang-Jiang
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/12/22
HER2
breast cancer
targeted therapy
drug resistance
overcoming strategies
Intervention of antimicrobial peptide usage on antimicrobial resistance in aquaculture
期刊论文
JOURNAL OF HAZARDOUS MATERIALS, 2022, 卷号: 427, 页码: 9
作者:
Lu, Jian
;
Zhang, Yuxuan
;
Wu, Jun
;
Wang, Jianhua
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/08/13
Antimicrobial peptide
Antibiotics
Antibiotic resistance genes
Aquaculture
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML)
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2021, 卷号: 897
作者:
Lu, Tingting
;
Cao, Jiangyan
;
Zou, Fengming
;
Li, Xixiang
;
Wang, Aoli
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/04/26
BCR-ABL
ABL mutants
Chronic myeloid leukemia
Kinase inhibitor
Imatinib resistance
Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:
Wang, Yu-xiang
;
Zhang, Xu
;
Ma, Qing-yang
;
Hu, Lan-dian
;
Zhang, Xi
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
YES1amplification confers trastuzumab-emtansine (T-DM1) resistance in HER2-positive cancer
期刊论文
BRITISH JOURNAL OF CANCER, 2020, 页码: 12
作者:
Wang, Lei
;
Wang, Quanren
;
Xu, Piaopiao
;
Fu, Li
;
Li, Yun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/12/24
Osimertinib successfully combats EGFR-negative glioblastoma cells by inhibiting the MAPK pathway
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020
作者:
Chen, Cheng
;
Cheng, Chuan-dong
;
Wu, Hong
;
Wang, Zuo-wei
;
Wang, Li
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/11/26
glioblastoma
osimertinib
temozolamide
MAPK-signaling pathway
MNK
eukaryotic translation initiation factor 4E
Structural and functional insights into a novel two-component endolysin encoded by a single gene in Enterococcus faecalis phage
期刊论文
PLOS PATHOGENS, 2020, 卷号: 16, 期号: 3, 页码: -
作者:
Zhou, B
;
Zhen, XK
;
Zhou, H
;
Zhao, FY
;
Fan, CP
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/09/06
CRYSTAL-STRUCTURE
BACTERIOPHAGE ENDOLYSINS
STAPHYLOCOCCUS-AUREUS
DIABETIC FOOT
LYSIN
RECOGNITION
MECHANISM
PROTEIN
Potential risks of microplastics combined with superbugs: Enrichment of antibiotic resistant bacteria on the surface of microplastics in mariculture system
期刊论文
Ecotoxicology and Environmental Safety, 2020, 卷号: 187, 期号: 0, 页码: 109852
作者:
Yuxuan Zhang
;
Lu J(吕剑)
;
Jun Wu
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/06/17
Microplastic
Antibiotic resistant bacteria
Superbugs
Multi-drug resistance
Antibiotic resistance genes
Mariculture
Antimicrobial Activity and Mechanism of Functionalized Quantum Dots
期刊论文
POLYMERS, 2019, 卷号: 11, 期号: 10, 页码: 13
作者:
Rajendiran, Keerthiga
;
Zhao, Zizhen
;
Pei, De-Sheng
;
Fu, Ailing
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/08/24
quantum dots
antimicrobial efficiency
multi-drug resistance
reactive oxygen species (ROS)
SHR-A1403, a novel c-mesenchymal-epithelial transition factor (c-Met) antibody-drug conjugate, overcomes AZD9291 resistance in non-small cell lung cancer cells overexpressing c-Met
期刊论文
CANCER SCIENCE, 2019, 页码: 11
作者:
Tong, Mengya
;
Gao, Mingzhao
;
Xu, Yongping
;
Fu, Li
;
Li, Yun
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
AZD9291
c-Met ADC
c-Met overexpression
resistance
SHR-A1403
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