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上海药物研究所 [22]
中南大学 [2]
复旦大学上海医学院 [2]
昆明医科大学 [2]
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期刊论文 [41]
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Dipeptidyl peptidase 4 inhibitor sitagliptin protected against dextran sulfate sodium-induced experimental colitis by potentiating the action of GLP-2
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Ning, Meng-meng
;
Yang, Wen-ji
;
Guan, Wen-bo
;
Gu, Yi-pei
;
Feng, Ying
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
ulcerative colitis
dextran sulfate sodium
dipeptidyl peptidase 4
sitagliptin
glucagon-like peptide-2
GLP-2(3-33)
apoptosis
proliferation
Saxagliptin alters bile acid profiles and yields metabolic benefits in drug-naive overweight or obese type 2 diabetes patient
期刊论文
JOURNAL OF DIABETES, 2019, 页码: 11
作者:
Li, Wen
;
Liu, Ruixin
;
Li, Xuelin
;
Tao, Bei
;
Zhai, Nan
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2019/12/02
bile acids
dipeptidyl peptidase-4 inhibitor
obesity
saxagliptin
type 2 diabetes
Alogliptin alleviates liver fibrosis via suppression of activated hepatic stellate cell
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 511, 期号: 2, 页码: 387-393
作者:
Zhang, Hanyan
;
Sun, Dandan
;
Wang, Guanzhen
;
Cui, Shichao
;
Field, Robert A.
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
DPP4
Alogliptin
Liver fibrosis
Hepatic stellate cell
Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 5, 页码: 2348-2361
作者:
Li, Shiliang
;
Qin, Chun
;
Cui, Shichao
;
Xu, Hongling
;
Wu, Fangshu
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases
期刊论文
Drug metabolism and disposition: the biological fate of chemicals, 2018
作者:
Kong, Fandi
;
Pang, Xiaoyan
;
Zhao, Jihui
;
Deng, Pan
;
Zheng, Mingyue
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2019/01/08
Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 12, 页码: 2131-2135
作者:
Li, Ning
;
Wang, Li-Jun
;
Jiang, Bo
;
Guo, Shu-Ju
;
Li, Xiang-Qian
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2019/08/21
Pyrimidinedionederivatives
DPP-4 inhibitor
Molecular hybrid
SARs
Type 2 diabetes
A manganese-salen complex as dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2018, 卷号: 120
作者:
Zhu, Ming-rong
;
Zhou, Jie
;
Jin, Yi
;
Gao, Li-Hui
;
Li, Ling
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/04
Manganese(II)
Schiff base complex
Enzyme inhibitors
Dipeptidyl peptidase IV
Molecular docking
Effect of sitagliptin, a DPP-4 inhibitor, against DENA-induced liver cancer in rats mediated via NF-kappa B activation and inflammatory cytokines
期刊论文
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2018, 卷号: 32, 期号: 12
作者:
Yang, Yongsheng
;
Yin, Fangying
;
Zheng, Ge
;
Jiang, Weidong
;
Wen, Dacheng
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/05
dipeptidyl-peptidase inhibitor 4 (DPP-4) inhibitor inflammation
lipid profile
liver cancer
nuclear factor-kappa B (NF-kappa B)
sitagliptin
Dipeptidyl Peptidase-4 Inhibitor Use is Associated with Decreased Risk of Fracture in Patients with Type 2 Diabetes: A Population-Based Cohort Study.
期刊论文
British journal of clinical pharmacology, 2018
作者:
Hou Wen-Hsuan
;
Chang Kai-Cheng
;
Li Chung-Yi
;
Ou Huang-Tz
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/26
CD26
antigen
*DIABETICS
*NON-insulin-dependent
diabetes
diagnosis
*METFORMIN
*DRUG
efficacy
Effect of Saxagliptin on Circulating Endothelial Progenitor Cells and Endothelial Function in Newly Diagnosed Type 2 Diabetic Patients
期刊论文
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, 2017, 卷号: 125, 期号: 6
作者:
Li, Fang
;
Chen, Jiachao
;
Leng, Fei
;
Lu, Zhiqiang
;
Ling, Yan
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/05
type 2 diabetes
endothelial progenitor cell
flow-mediated dilation
dipeptidyl peptidase-4 inhibitor
saxagliptin
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