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CORC

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1-Phenyl-dihydrobenzoindazoles as novel colchicine site inhibitors: Structural basis and antitumor efficacy 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 177, 页码: 448-456
作者:  Jiang, Junhang;  Zhang, Hao;  Wang, Chongqing;  Zhang, Qingsen;  Fang, Shaoyu
收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01
Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 7, 页码: 10
作者:  Zhang, Yu;  Goto, Masuo;  Oda, Akifumi;  Hsu, Pei-Ling;  Guo, Ling-Li
收藏  |  浏览/下载：67/0  |  提交时间：2019/07/29
Synthesis and bioevaluation of diarylpyrazoles as antiproliferative agents 期刊论文
European Journal of Medicinal Chemistry, 2019
作者:  Chao Wang;  Shuang Yang;  Jianan Du;  Jia Ni;  Yue Wu
收藏  |  浏览/下载：7/0  |  提交时间：2019/12/13
Discover 4 beta-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 170, 页码: 73-86
作者:  Zhao, Wei;  He, Long;  Xiang, Tian-Le;  Tang, Ya-Jie
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/11
Tubulin colchicine site binding agent LL01 displays potent antitumor efficiency both in vitro and in vivo with suitable drug-like properties 期刊论文
Investigational New Drugs, 2019
作者:  Wu J.-D.;  Cui Y.-J.;  Zhou Y.-G.;  Tang L.-Q.;  Zhang C.-M.
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/11
Identification of novel and potent small-molecule inhibitors of tubulin with antitumor activities by virtual screening and biological evaluations 期刊论文
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, 2019, 卷号: 33, 期号: 7, 页码: 659-664
作者:  Liu, Guangpu;  Jiao, Yang;  Huang, Chunxi;  Chang, Ping
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11
Discover 4β-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain 期刊论文
European Journal of Medicinal Chemistry, 2019, 页码: 73-86
作者:  Zhao W.;  He L.;  Xiang T.-L.;  Tang Y.-J.
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11
Design, synthesis and biological evaluation of quinoline-indole derivatives as anti-tubulin agents targeting the colchicine binding site 期刊论文
European Journal of Medicinal Chemistry, 2019, 卷号: Vol.163, 页码: 428-442
作者:  Wenlong Li;  Wen Shuai;  Honghao Sun;  Feijie Xu;  Yi Bi
收藏  |  浏览/下载：13/0  |  提交时间：2019/12/13
Synthesis, molecular properties prediction and biological evaluation of indole-vinyl sulfone derivatives as novel tubulin polymerization inhibitors targeting the colchicine binding site 期刊论文
Bioorganic Chemistry, 2019, 卷号: Vol.85, 页码: 49-59
作者:  Wenlong Li;  Honghao Sun;  Feijie Xu;  Wen Shuai;  Jie Liu
收藏  |  浏览/下载：30/0  |  提交时间：2019/12/13
The Structure of MT189-Tubulin Complex Provides Insights into Drug Design 期刊论文
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 9, 页码: 1069-1073
作者:  Li, Zhongping;  Ma, Lingling;  Wu, Chengyong;  Meng, Tao;  Ma, Lanping
收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01

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