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CORC

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Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation 期刊论文
JOURNAL OF ADVANCED RESEARCH, 2021, 卷号: 33, 页码: 241-251
作者:  Li, Heng;  Zhang, Xianglei;  Xiang, Caigui;  Feng, Chunlan;  Fan, Chen
收藏  |  浏览/下载：86/0  |  提交时间：2021/11/04
Inhibition of PDE4 by apremilast attenuates skin fibrosis through directly suppressing activation of M1 and T cells 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:  Lu, Qiu-kai;  Fan, Chen;  Xiang, Cai-gui;  Wu, Bing;  Lu, Hui-min
收藏  |  浏览/下载：57/0  |  提交时间：2021/06/11
Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:  Zhang, Rui;  Li, Heng;  Zhang, Xianglei;  Li, Jian;  Su, Haixia
收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24
Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:  Weng, Zhiying;  Xu, Guowei;  Chen, Dingyuan;  Yang, Yaqing;  Song, Gao
收藏  |  浏览/下载：17/0  |  提交时间：2020/03/18
Ligand-induced activation of ERK1/2 signaling by constitutively active G(s)-coupled 5-HT receptors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1157-1167
作者:  Liu, Ping;  Yin, Yu-ling
收藏  |  浏览/下载：20/0  |  提交时间：2020/07/01
5-HT4R  5-HT6R  5-HT7AR  5-HT  ERK1/2  G(s)  beta-arrestin  Fyn  Src  
cAMP-modulated biomimetic ionic nanochannels based on a smart polymer 期刊论文
JOURNAL OF MATERIALS CHEMISTRY B, 2019, 卷号: 7, 期号: 23, 页码: 3710-3715
作者:  Chen, Zhixiang;  Sun, Taolei;  Qing, Guangyan
收藏  |  浏览/下载：70/0  |  提交时间：2019/12/02
Pulsed electromagnetic fields promote bone formation by activating the sAC-cAMP-PKA-CREB signaling pathway 期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: 234, 期号: 3, 页码: 2807-2821
作者:  Wang, Yuan-Yuan;  Pu, Xiu-Ying;  Shi, Wen-Gui;  Fang, Qing-Qing;  Chen, Xin-Ru
收藏  |  浏览/下载：4/0  |  提交时间：2019/11/15
Pulsed electromagnetic fields promote bone formation by activating the sAC-cAMP-PKA-CREB signaling pathway 期刊论文
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 卷号: 234, 期号: 3, 页码: 2807-2821
作者:  Wang, Yuan-Yuan
收藏  |  浏览/下载：7/0  |  提交时间：2022/03/01
Changes in key enzyme activities and metabolites during in vitro maturation of Apostichopus japonicus oocyte under desiccation stress 期刊论文
AQUACULTURE RESEARCH, 2019, 卷号: 50, 期号: 2, 页码: 400-411
作者:  Liu, Shilin;  Lin, Chenggang;  Qu, Hongxia;  Sun, Jingchun;  Ru, Xiaoshang
收藏  |  浏览/下载：72/0  |  提交时间：2019/08/27
Evaluation of selected traditional Chinese medical extracts for bone mineral density maintenance: A mechanistic study. 期刊论文
Journal of traditional and complementary medicine, 2019, 卷号: 9, 期号: 3
作者:  Rebhun John F;  Du Qin;  Hood Molly;  Guo Hailing;  Glynn Kelly M
收藏  |  浏览/下载：44/0  |  提交时间：2019/12/05
Anti-inflammatory  BMD, bone mineral density  BSA, bovine serum albumin  Bmp4, bone morphogenic protein 4  CRE, cyclic adenosine monophosphate response element  CREB, cyclic adenosine monophosphate response element binding protein  DEXA, dual-energy X-ray absorptiometry  DMSO, Dimethyl sulfoxide  Drynaria fortunei  E2, estradiol  ER, estrogen receptor  ERE, estrogen response element  Epimedium brevicornu  Estrogenic  FBS, fetal bovine serum  Fsk, forskolin  Hprt, hypoxanthine-guanine phosphoribosyl-transferase  IL-1, interleukin 1  LBD, ligand binding domain  LBM, low bone mass  M-CSF, macrophage colony-stimulating factor  MAPK, mitogen activated protein kinase  NF-κβ, nuclear factor kappa beta  OP, osteoporosis  Osteoporosis  PTH, parathyroid hormone  PTHrp, PTH related peptide  RANKL, receptor activator of nuclear factor kappa beta ligand  RLU, relative luminescence unit  ROI, region of interest  Runx2, runt-related transcription factor 2  SFM, serum free media  TCM, traditional Chinese medicine  TNFα, tumor necrosis factor alpha  TRAP, tartrate-resistant acid phosphatase  UAS, upstream activating sequence  cAMP, cyclic adenosine monophosphate  qPCR, quantitative polymerase chain reaction  

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