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1,2-Difunctionalized bicyclo[1.1.1]pentanes: Long-sought-after mimetics for ortho/ meta-substituted arenes 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 28, 页码: 5
作者:  Zhao, Jin-Xin;  Chang, Yu-Xuan;  He, Chi;  Burke, Benjamin J.;  Collins, Michael R.
收藏  |  浏览/下载:17/0  |  提交时间:2021/11/04
Allenamide as a bioisostere of acrylamide in the design and synthesis of targeted covalent inhibitors 期刊论文
MEDCHEMCOMM, 2018, 卷号: 9, 期号: 2, 页码: 244-253
作者:  Chen, Deheng;  Guo, Dexiang;  Yan, Ziqin;  Zhao, Yujun
收藏  |  浏览/下载:32/0  |  提交时间:2019/01/08
Melatonin-directed micellization: a case for tryptophan metabolites and their classical bioisosteres as templates for the self-assembly of bipyridinium-based supramolecular amphiphiles in water. 期刊论文
Soft Matter, 2018, 卷号: Vol.14 No.15, 页码: 2893-2905
作者:  Wang, Z.a;  Cui, H.b,e;  Sun, Z.a;  Roch, L.M.a,c,f;  Goldner, A.N.b,g
收藏  |  浏览/下载:3/0  |  提交时间:2019/11/21
In silico design of colchicine-based bioisosteric inhibitors of tubulin for the treatment of rheumatoid arthritis 期刊论文
MOLECULAR MEDICINE REPORTS, 2017, 卷号: 16, 页码: 4823-4828
作者:  Wang, Li;  Yang, Hao-Jie;  Tu, Ran;  Shen, Min;  Liu, Dan
收藏  |  浏览/下载:3/0  |  提交时间:2019/11/26
Deoxygenative gem-difluoroolefination of carbonyl compounds with (chlorodifluoromethyl)trimethylsilane and triphenylphosphine 期刊论文
Beilstein J. Org. Chem., 2014, 卷号: 10, 页码: 344-351
作者:  Wang F(王飞);  Li LC(李铃春);  Ni CF(倪传法);  Hu JB(胡金波)
收藏  |  浏览/下载:34/0  |  提交时间:2016/08/30
Tetrazole and triazole as bioisosteres of carboxylic acid: Discovery of diketo tetrazoles and diketo triazoles as anti-HCV agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 16
作者:  Song, Wu-Hui;  Liu, Ming-Ming;  Zhong, Dong-Wei;  Zhu, Ye-lin;  Bosscher, Mike
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/19
Thiadiazole—a Promising Structure in Medicinal Chemistry 期刊论文
ChemMedChem, 2013, 卷号: 8, 期号: 1, 页码: 27-41
作者:  Yijing Li;  Jingkun Geng;  Yang Liu
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/23
Synthesis of C-4-modified zanamivir analogs as neuraminidase inhibitors and their anti-AIV activities 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 54, 页码: 764-770
作者:  Ye, Deju;  Shin, Woo-Jin;  Li, Ning;  Tang, Wei;  Feng, Enguang
收藏  |  浏览/下载:12/0  |  提交时间:2019/01/08
Novel dimeric aryldiketo containing inhibitors of HIV-1 integrase: Effects of the phenyl substituent and the linker orientation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 卷号: 16, 期号: 16, 页码: 7777-7787
作者:  Zeng, Li-Fan;  Jiang, Xiao-Hua;  Sanchez, Tino;  Zhang, Hu-Shan;  Dayam, Raveendra
收藏  |  浏览/下载:13/0  |  提交时间:2019/01/08
Three-dimensional holographic vector of atomic interaction field for quantitative structure-activity relationship of Aza-bioisosteres of anthrapyrazoles (Aza-APs) 期刊论文
2008, 卷号: 26, 页码: 1252-1258
作者:  Xu Luo-nan[1,2];  Liang Gui-Zhao[2];  Li Zhi-liang[1,2];  Wang Juan[1];  Zhou Peng[1]
收藏  |  浏览/下载:2/0  |  提交时间:2019/11/28


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