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An enhanced strategy integrating offline two-dimensional separation with data independent acquisition mode and deconvolution: Characterization of metabolites of Uncaria rhynchophylla in rat plasma as a case
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1181, 页码: 8
作者:
Li, Haojv
;
Wei, Wenlong
;
Li, Zhenwei
;
Wang, Mengyuan
;
Wei, Xuemei
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/11/04
Off-line 2D separation system
Metabolites characterization in vivo
Data independent acquisition
Multi-dimensional deconvolution
Uncaria rhynchophylla
Fast determination of 16 circulating neurotransmitters and their metabolites in plasma samples of spontaneously hypertensive rats intervened with five different Uncaria
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2021, 卷号: 1179, 页码: 9
作者:
Gao, Lei
;
Zhang, Zijia
;
Feng, Zijin
;
Wei, Wenlong
;
Wu, Wenyong
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/11/04
Neurotransmitters
LC-MS
Hypertension
Uncaria
Spontaneously hypertensive rats
Systematic comparison of metabolic differences of Uncaria rhynchophylla in rat, mouse, dog, pig, monkey and human liver microsomes
期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 页码: 7
作者:
Li, Hao-Jv
;
Wei, Wen-Long
;
Li, Zhen-Wei
;
Yao, Chang-Liang
;
Wang, Meng-Yuan
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2020/12/24
Uncaria rhynchophylla
Indole alkaloids
Mass defect filter
Time-staggered targeted ion lists
Metabolite identification
Liver microsomes
A Network-Based Approach to Explore the Mechanisms of Uncaria Alkaloids in Treating Hypertension and Alleviating Alzheimer's Disease
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 5, 页码: 19
作者:
Wu, Wenyong
;
Zhang, Zijia
;
Li, Feifei
;
Deng, Yanping
;
Lei, Min
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/07/01
Uncaria alkaloids
network pharmacology
hypertension
Alzheimer's disease
butyrylcholinesterase
molecular docking
A metabolomics strategy for authentication of plant medicines with multiple botanical origins, a case study of Uncariae Rammulus Cum Uncis
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2020, 卷号: 43, 期号: 6, 页码: 1043-1050
作者:
Pan, Huiqin
;
Yao, Changliang
;
Yao, Shuai
;
Yang, Wenzhi
;
Wu, Wanying
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
discrimination and recognition
herbal medicine
multiple botanical origins
pattern recognition
Antiepileptic geissoschizine methyl ether is an inhibitor of multiple neuronal channels
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Xie, Zhu-qing
;
Tian, Xiao-ting
;
Zheng, Yue-ming
;
Zhan, Li
;
Chen, Xue-qin
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
geissoschizine methyl ether
Uncaria rhynchophyll
antiepileptic drug
hippocampal neurons
action potential
nicotinic acetylcholine receptors
voltage-gated ion channels
mouse seizure model
Antioxidant activity of extracts from Uncaria scandens
会议论文
Changchun, Jilin, China, June 28, 2019 - June 30, 2019
作者:
Zhang, Fulu
;
Yang, Aimei
;
Ma, Songyao
;
Shang, Huilan
;
Wang, Zhihui
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/11/15
Energy resources
Environmental technology
Ethanol
Free radicals
Anti-oxidant activities
Anti-oxidation activities
DPPH free radicals
Ethanol extract
Ethyl acetates
Hydroxyl radicals
Petroleum ether
Reducing power
Dissecting the Metabolic Phenotype of the Antihypertensive Effects of Five Uncaria Species on Spontaneously Hypertensive Rats
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 11
作者:
Feng, Zijin
;
Hou, Jinjun
;
Yu, Yang
;
Wu, Wenyong
;
Deng, Yanping
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Uncaria Stem with Hooks
multiple botanical origins
spontaneously hypertensive rats
systolic blood pressure
metabonomics
indole alkaloids
Secondary Metabolites and PI3K Inhibitory Activity of Colletotrichum gloeosporioides, a Fungal Endophyte of Uncaria rhynchophylla
期刊论文
CURRENT MICROBIOLOGY, 2019, 卷号: 76, 期号: 7, 页码: 904-908
作者:
Yang, Zhong-Duo
;
Li, Zhi-Jie
;
Zhao, Jun-Wen
;
Sun, Jian-Hui
;
Yang, Li-Jun
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2019/11/15
Secondary Metabolites and PI3K Inhibitory Activity of Colletotrichum gloeosporioides, a Fungal Endophyte of Uncaria rhynchophylla
期刊论文
Current Microbiology, Current Microbiology, Current Microbiology, Current Microbiology, 2019, 2019, 2019, 2019, 卷号: 76, 76, 76, 76, 期号: 7, 页码: 904-908, 904-908, 904-908, 904-908
作者:
Yang ZD(杨中铎)
收藏
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浏览/下载:4/0
  |  
提交时间:2020/11/09
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