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上海药物研究所 [5]
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Characterization of the metabolites of tirabrutinib generated from rat, dog and human liver microsomes using ultra-high-performance liquid chromatography combined with high-resolution mass spectrometry
期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2022, 卷号: 36
作者:
Zhang, Hongjian
;
Hu, Zhen
;
Zhang, Huiping
;
Sun, Xiyan
;
Yang, Jianming
收藏
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浏览/下载:42/0
  |  
提交时间:2022/03/28
An Integrated Strategy to Identify and Quantify the Quality Markers of Xinkeshu Tablets Based on Spectrum-Effect Relationship, Network Pharmacology, Plasma Pharmacochemistry, and Pharmacodynamics of Zebrafish
期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Wei, YH
;
Nie, L
;
Gao, LL
;
Zhong, L
;
Sun, ZY
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浏览/下载:18/0
  |  
提交时间:2022/12/02
Site-specific protein modification by 3-n-butylphthalide in primary hepatocytes: Covalent protein adducts diminished by glutathione and N-acetylcysteine
期刊论文
LIFE SCIENCES, 2021, 卷号: 287, 页码: 14
作者:
Xue, Yaru
;
Ren, Xuelian
;
Zhu, Zhengdan
;
Lei, Peng
;
Liu, Mengling
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浏览/下载:39/0
  |  
提交时间:2022/01/18
3-n-butylphthalide
Hepatotoxicity
Oxidative stresses
Covalent protein modification
Drug-drug interaction
The maximum carbonyl ratio (MCR) as a new index for the structural classification of secondary organic aerosol components
期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2021, 卷号: 35, 期号: 14, 页码: 11
作者:
Zhang, Yun
;
Wang, Kai
;
Tong, Haijie
;
Huang, Ru-Jin
;
Hoffmann, Thorsten
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浏览/下载:72/0
  |  
提交时间:2021/12/06
瘤果黑种草降糖部位的制备及对糖尿病小鼠保护作用研究
学位论文
中国科学院新疆理化技术研究所: 中国科学院大学, 2021
作者:
马冶
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浏览/下载:42/0
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提交时间:2021/08/27
瘤果黑种草
工艺优化
糖尿病肾病保护
糖尿病心肌损伤
Optimization of microwave-assisted extraction using response surface methodology and the potential anti-diabetic efficacy of Nigella glandulifera Freyn determined using the spectrum-effect relationship
期刊论文
INDUSTRIAL CROPS AND PRODUCTS, 2020, 卷号: 153, 期号: 10, 页码: 1-10
作者:
Ma, Y (Ma, Ye)[ 1,2 ]
;
Li, J (Li, Jun)[ 1 ]
;
Tong, F (Tong, Fei)[ 1 ]
;
Xin, XL (Xin, Xue-Lei)[ 1 ]
;
Aisa, HA (Aisa, Haji Akber)[ 1 ]
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浏览/下载:99/0
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提交时间:2020/07/06
Nigella glandulifera Freyn
Microwave-assisted extraction
Response surface methodology
Aldose reductase inhibition
Spectrum-effect relationship
Profiling and identification of aqueous extract of Cordyceps sinensis by ultra-high performance liquid chromatography tandem quadrupole-orbitrap mass spectrometry
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 8, 页码: 631-640
作者:
Yao Chang-Liang
;
Qian Zheng-Ming
;
Tian Wen-Shuai
;
Xu Xiao-Qian
;
Yan Yu
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  |  
浏览/下载:4/0
  |  
提交时间:2020/07/01
Aqueous extract
Cordyceps sinensis
Dipeptides
Nucleosides
Integrated liquid chromatography-mass spectrometry and nuclear magnetic resonance spectra for the comprehensive characterization of various components in the Shuxuening injection
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2019, 卷号: 1599
作者:
Yu, Shuting
;
Li, Jing
;
Guo, Liang
;
Di, Caixia
;
Qin, Xuemei
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  |  
浏览/下载:13/0
  |  
提交时间:2019/12/05
Shuxuening injection
Ginkgo biloba
Chemical composition
NMR
UHPLC-Q-Orbitrap HRMS
Identification and Quantification of Bioactive Compounds in Diaphragma juglandis Fructus by UHPLC-Q-Orbitrap HRMS and UHPLC-MS/MS
期刊论文
Journal of Agricultural and Food Chemistry, 2019, 卷号: 67, 期号: 13, 页码: 3811-3825
作者:
Liu R.
;
Zhao Z.
;
Dai S.
;
Che X.
;
Liu W.
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  |  
浏览/下载:114/0
  |  
提交时间:2019/12/11
bioactive compounds
Diaphragma juglandis fructus
identification
quantification
UHPLC-MS/MS
UHPLC-Q-Orbitrap HRMS
An Integrated Approach to Characterize Intestinal Metabolites of Four Phenylethanoid Glycosides and Intestinal Microbe-Mediated Antioxidant Activity Evaluation In Vitro Using UHPLC-Q-Exactive High-Resolution Mass Spectrometry and a 1,1-Diphenyl-2
期刊论文
2019, 卷号: 10, 页码: 826
作者:
Wang, Xiaoming
;
Chang, Xiaoyan
;
Luo, Xiaomei
;
Su, Meifeng
;
Xu, Rong
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  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
intestinal microbial metabolism
four phenylethanoid glycosides
UHPLC-Q-Exactive Orbitrap HRMS
antioxidant activities
structure-activity relationship
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