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浏览/检索结果:
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High-throughput prediction and characterization of antimicrobial peptides from multi-omics datasets of Chinese tubular cone snail (Conus betulinus)
期刊论文
FRONTIERS IN MARINE SCIENCE, 2022, 卷号: 9, 页码: 13
作者:
Li, Ruihan
;
Huang, Yu
;
Peng, Chao
;
Gao, Zijian
;
Liu, Jie
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2023/12/13
Conus betulinus
antimicrobial peptide
multi-omics
in silico prediction
in vitro assessment
Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor Agonists
期刊论文
PHARMACEUTICALS, 2022, 卷号: 15
作者:
Sun, Lei
;
Zheng, Zhi-Ming
;
Shao, Chang-Sheng
;
Zhang, Zhi-Yong
;
Li, Ming-Wei
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2022/12/22
glucagon-like peptide-1
GLP-1 receptor agonist
functional protein design
molecular dynamics simulation
long-acting antihyperglycemic
GM-Pep: A High Efficiency Strategy to De Novo Design Functional Peptide Sequences
期刊论文
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2022, 卷号: 62, 期号: 10, 页码: 2617-2629
作者:
Chen, Qushuo
;
Yang, Changyan
;
Xie, Yihao
;
Wang, Yuqiang
;
Li, Xiaoxu
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2022/06/21
BioactivityDrug interactionsLearning systemsToxicity
Auto encodersComputation methodsDe novo designFunctional peptidesHigher efficiencyMulti-classifierPeptide sequencesPeptide therapeuticsTherapeutic agentsTherapeutic peptides
Targeted-detection and sequential-treatment of small hepatocellular carcinoma in the complex liver environment by GPC-3-targeted nanoparticles
期刊论文
Journal of Nanobiotechnology, 2022, 卷号: 20, 期号: 1, 页码: 20
作者:
Deng,Han
;
Shang,Wenting
;
Wang,Kun
;
Guo,Kunxiong
;
Liu,Yu
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  |  
浏览/下载:22/0
  |  
提交时间:2022/06/06
Small hepatocellular carcinoma
Complex liver environment
Targeted detection
Dynamic contrast-enhanced photoacoustic imaging
Sequential catalysis-targeted therapy
Biomimetic manganese-eumelanin nanocomposites for combined hyperthermia-immunotherapy against prostate cancer
期刊论文
Journal of Nanobiotechnology, 2022, 卷号: 20, 期号: 1
作者:
Liu,Yu
;
Shang,Wenting
;
Liu,Heng
;
Hui,Hui
;
Wu,Jun
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  |  
浏览/下载:43/0
  |  
提交时间:2022/02/16
Tumor-associated macrophages
Immunomodulation
Hyperthermia-immunotherapy
Eumelanin
Prostate cancer
Distal mutation V486M disrupts the catalytic activity of DPP4 by affecting the flap of the propeller domain
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Li, Teng-teng
;
Peng, Cheng
;
Wang, Ji-qiu
;
Xu, Zhi-jian
;
Su, Ming-bo
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  |  
浏览/下载:42/0
  |  
提交时间:2022/01/18
DPP4
distal mutation
enzymatic activity
molecular dynamics simulation
structure-function mechanism
Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site
期刊论文
ACS CHEMICAL BIOLOGY, 2021, 卷号: 16, 期号: 11, 页码: 2444-2452
作者:
Wang, Jiang
;
Yang, Dehua
;
Cheng, Xi
;
Yang, Linlin
;
Wang, Zhaohui
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/01/04
Genetically-engineered "all-in-one" vaccine platform for cancer immunotherapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 11, 页码: 3622-3635
作者:
Wu, Aihua
;
Chen, Yingzhi
;
Wang, Hairui
;
Chang, Ya
;
Zhang, Meng
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/01/18
Trichosanthin
Legumain
TRP2
Transcutaneous immunization
Adjuvant
Cancer vaccine
Protein engineering
Recombinant cancer nanovaccine for targeting tumor-associated macrophage and remodeling tumor microenvironment
期刊论文
NANO TODAY, 2021, 卷号: 40, 页码: 14
作者:
Tang, Yisi
;
Fan, Wufa
;
Chen, Guihua
;
Zhang, Meng
;
Tang, Xueping
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/12/01
Cancer therapeutic vaccine
Legumain
Tumor-associated macrophage
Trichosanthin
Liposome
Adjuvant
Structural insights into ligand recognition and activation of the melanocortin-4 receptor
期刊论文
CELL RESEARCH, 2021, 页码: 13
作者:
Zhang, Huibing
;
Chen, Li-Nan
;
Yang, Dehua
;
Mao, Chunyou
;
Shen, Qingya
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  |  
浏览/下载:33/0
  |  
提交时间:2021/11/04
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