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上海药物研究所 [19]
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海洋研究所 [4]
合肥物质科学研究院 [3]
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Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge
期刊论文
PLOS COMPUTATIONAL BIOLOGY, 2021, 卷号: 17, 期号: 9, 页码: 19
作者:
Xiong, Zhaoping
;
Jeon, Minji
;
Allaway, Robert J.
;
Kang, Jaewoo
;
Park, Donghyeon
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/11/04
A nanoselenium-coating biomimetic cytomembrane nanoplatform for mitochondrial targeted chemotherapy- and chemodynamic therapy through manganese and doxorubicin codelivery
期刊论文
JOURNAL OF NANOBIOTECHNOLOGY, 2021, 卷号: 19
作者:
Xiao, Jianmin
;
Yan, Miao
;
Zhou, Ke
;
Chen, Hui
;
Xu, Zhaowei
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/08/30
Cell membrane
Reactive oxygen species
Superoxide dismutase-1
Glutathione peroxidase 4
Dual-mode therapeutic pathways
Drug delivery system
Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors
期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 3, 页码: 781-794
作者:
Wu, Xiaowei
;
Dai, Mengdi
;
Cui, Rongrong
;
Wang, Yulan
;
Li, Chunpu
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
Tyrosine kinase
Covalent FGFR inhibitors
Virtual screening
Pyrazolo[3,4-d] pyridazinone
Structure-activity relationships
Antitumor efficacy
Structural insights into the human D1 and D2 dopamine receptor signaling complexes
期刊论文
CELL, 2021, 卷号: 184, 期号: 4, 页码: 931-+
作者:
Zhuang, Youwen
;
Xu, Peiyu
;
Mao, Chunyou
;
Wang, Lei
;
Krumm, Brian
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  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
RNA-dependent RNA polymerase: Structure, mechanism, and drug discovery for COVID-19
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021, 卷号: 538, 页码: 47-53
作者:
Jiang, Yi
;
Yin, Wanchao
;
Xu, H. Eric
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  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
COVID-19
SARS-CoV-2
RNA-dependent RNA polymerase
Structure
RNA recognition
Remdesivir
Reprogramming the immunosuppressive microenvironment of IDH1 wild-type glioblastoma by blocking Wnt signaling between microglia and cancer cells
期刊论文
ONCOIMMUNOLOGY, 2021, 卷号: 10, 期号: 1, 页码: 13
作者:
Fan, Dandan
;
Yue, Qi
;
Chen, Jian
;
Wang, Cong
;
Yu, Ruilin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
Wnt/beta-catenin
IDH1-wildtype glioblastoma
Microglia
Phenotypic polarization
Identification of miR-4644 as a suitable endogenous normalizer for circulating miRNA quantification in hepatocellular carcinoma
期刊论文
Journal of Cancer, 2020, 卷号: 11
作者:
朱灵(zhu ling)
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  |  
浏览/下载:60/0
  |  
提交时间:2020/11/19
circulating microRNA
endogenous control
normalization in RT-qPCR
hepatocellular carcinoma
Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: Network -molecular docking-LC-MSE analysis
期刊论文
JOURNAL OF INTEGRATIVE MEDICINE-JIM, 2020, 卷号: 18, 期号: 3, 页码: 229-241
作者:
Zhang, Zi-jia
;
Wu, Wen-yong
;
Hou, Jin-jun
;
Zhang, Lin-lin
;
Li, Fei-fei
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  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
Lung-toxin Dispelling Formula No. 1
COVID-19
3C-like protease
Network pharmacology
Molecular docking
Meridian tropism
Research Progress of Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder
期刊论文
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2020, 卷号: 47, 期号: 4, 页码: 319-334
作者:
Lu Ping-Ping
;
Wang Liang
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/08/24
posttraumatic stress disorder
transcranial magnetic stimulation
cognitive function
brain function
stimulation pattern
Identification and structural insight of an effective PPAR gamma modulator with improved therapeutic index for anti-diabetic drug discovery
期刊论文
CHEMICAL SCIENCE, 2020, 卷号: 11, 期号: 8, 页码: 2260-2268
作者:
Jiang, Haowen
;
Zhou, X. Edward
;
Shi, Jingjing
;
Zhou, Zhi
;
Zhao, Guanguan
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
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