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CORC

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Scalable Process for Making 5,7-Dichlorotetrahydroisoquinoline-6-carboxylic Acid Using Methylene as the Protecting Group 期刊论文
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 11, 页码: 2447-2452
作者:  Xu, Wanbin;  Gong, Xudong;  Odilov, Abdullajon;  Hu, Tianwen;  Jiang, Xiangrui
收藏  |  浏览/下载：50/0  |  提交时间：2022/01/18
Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:  Zhang, Rui;  Li, Heng;  Zhang, Xianglei;  Li, Jian;  Su, Haixia
收藏  |  浏览/下载：22/0  |  提交时间：2021/05/24
On-DNA Cross-Dehydrogenative Coupling Reaction toward the Synthesis of Focused DNA-Encoded Tetrahydroisoquinoline Libraries 期刊论文
ORGANIC LETTERS, 2020, 卷号: 22, 期号: 15, 页码: 5721-5725
作者:  Wen, Xin;  Duan, Zhiqiang;  Liu, Jiaxiang;  Lu, Weiwei;  Lu, Xiaojie
收藏  |  浏览/下载：18/0  |  提交时间：2020/12/24
Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5579-5593
作者:  Zhang, Xianglei;  Dong, Guangyu;  Li, Heng;  Chen, Wuyan;  Li, Jian
收藏  |  浏览/下载：14/0  |  提交时间：2020/07/01
Design and Synthesis of Potent, Selective Inhibitors of Protein Arginine Methyltransferase 4 against Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 11, 页码: 5414-5433
作者:  Guo, Zuhao;  Zhang, Zhuqing;  Yang, Hong;  Cao, Danyan;  Xu, Xiaowei
收藏  |  浏览/下载：16/0  |  提交时间：2020/07/01
Discovery of 2-substituted-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxamide as potent and selective protein arginine methyltransferases 5 inhibitors: Design, synthesis and biological evaluation 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 164, 页码: 317-333
作者:  Shao, Jingwei;  Zhu, Kongkai;  Du, Daohai;  Zhang, Yuanyuan;  Tao, Hongrui
收藏  |  浏览/下载：35/0  |  提交时间：2020/07/01
Discovery and development of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as Bcl-2/Mcl-1 inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 88
作者:  Liu, Renshuai;  Liu, Lulu;  Yang, Xinying;  Fang, Hao
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/11
Synthesis of 4-Aryl Isoquinolinedione Derivatives by a Palladium-Catalyzed Coupling Reaction of Aryl Halides with Isoquinoline-1,3(2H,4H)-diones 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 83, 期号: 6, 页码: 3348-3353
作者:  Yang, Yuanyong;  Li, Yingxian;  Cheng, Cheng;  Yang, Guo;  Zhang, Jiquan
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08
Design, synthesis and pharmacological evaluation of new acyl sulfonamides as potent and selective Bcl-2 inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 2, 页码: 443-454
作者:  Liu, Xiaohua;  Zhang, Yu;  Huang, Wenjing;  Tan, Wenfu;  Zhang, Ao
收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08
Organometallic Gold(III) Complexes Similar to Tetrahydroisoquinoline Induce ER-Stress-Mediated Apoptosis and Pro-Death Autophagy in A549 Cancer Cells 期刊论文
Journal of Medicinal Chemistry, 2018, 卷号: 61, 期号: 8, 页码: 3478-3490
作者:  Huang, Ke-Bin;  Wang, Feng-Yang;  Tang, Xiao-Ming;  Feng, Hai-Wen;  Chen, Zhen-Feng*
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/03

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