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上海药物研究所 [19]
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Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1
期刊论文
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Wang, Zuo-wei
;
Zou, Feng-ming
;
Wang, Ao-li
;
Yang, Jing
;
Jin, Rui
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/22
AZD4547
RIPK1
inhibitors
SIRS model
anti-necroptosis
Regulation of the Cell Cycle, Apoptosis, and Proline Accumulation Plays an Important Role in the Stress Response of the Eastern Oyster Crassostrea Virginica
期刊论文
FRONTIERS IN MARINE SCIENCE, 2022, 卷号: 9, 页码: 12
作者:
Li, Cui
;
Wang, Haiyan
;
Guo, Ximing
收藏
  |  
浏览/下载:181/0
  |  
提交时间:2022/08/17
stress
transcriptome
cell cycle control
apoptosis
growth
immune function
epigenetic modification
Synthesis of pyranochalcone derivatives and their inhibitory effect on NF-kappa B activation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 42, 页码: 5
作者:
Ajiaikebaier, Dilidaer
;
Li, Zuopeng
;
Lin, TzuChun
;
Sun, Xinyu
;
Wang, Bianlin
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/08/17
Pyranochalcone derivatives
NF-kappa B inhibitor
Anti-inflammatory
Inflammatory factor
Diversity-oriented synthesis of cembranoid derivatives as potential anti-inflammatory agents
期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 111, 页码: 8
作者:
Zhang, Cong
;
Li, Heng
;
Liu, Jin
;
Liu, Moting
;
Zhang, Hao
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  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
Marine natural product
Cembranoid
Anti-inflammation
molecular docking
structuremodification
Structure Activity Relationship
Pharmacological inhibition of NF-kappa B-inducing kinase (NIK) with small molecules for the treatment of human diseases
期刊论文
RSC MEDICINAL CHEMISTRY, 2021, 卷号: 12, 期号: 4, 页码: 552-565
作者:
Cheng, Jing
;
Feng, Xuexin
;
Li, Zhiqiang
;
Zhou, Feilong
;
Yang, Jin-Ming
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2021/08/17
Design, synthesis, and biological evaluation of tetrahydroisoquinolines derivatives as novel, selective PDE4 inhibitors for antipsoriasis treatment
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 211, 页码: 20
作者:
Zhang, Rui
;
Li, Heng
;
Zhang, Xianglei
;
Li, Jian
;
Su, Haixia
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2021/05/24
PDE4 inhibitors
Tetrahydroisoquinoline
Antipsoriasis
Synthesis of pyranochalcone derivatives and their inhibitory effect on NF-kappa B activation
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 42, 期号: 6, 页码: 1-5
作者:
Ajiaikebaier, D (Ajiaikebaier, Dilidaer) 1 , 3
;
Li, ZP (Li, Zuopeng) 2
;
Lin, TC (Lin, TzuChun) 1
;
Sun, XY (Sun, Xinyu) 1
;
Wang, BL (Wang, Bianlin) 2
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/07/27
Pyranochalcone derivativesNF-kappa B inhibitorAnti-inflammatoryInflammatory factor
Natural Potent NAAA Inhibitor Atractylodin Counteracts LPS-Induced Microglial Activation
期刊论文
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 9
作者:
Yang, Longhe
;
Ji, Chunyan
;
Li, Yitian
;
Hu, Fan
;
Zhang, Fang
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/12/10
NAAA inhibitor
atractylodin
>
anti-inflammation
microglia
traditional Chinese medicine
Identification of new dual FABP4/5 inhibitors based on a naphthalene-1-sulfonamide FABP4 inhibitor
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 19, 页码: 16
作者:
He, Yulong
;
Dou, Huixia
;
Gao, Dingding
;
Wang, Ting
;
Zhang, Mingming
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Dual FABP4/5 inhibitor
Structure-based design
Lipolysis inhibition
Anti-inflammatory effects
Inhibitory Effect of Metalloproteinase Inhibitors on Skin Cell Inflammation Induced by Jellyfish Nemopilema nomurai Nematocyst Venom
期刊论文
TOXINS, 2019, 卷号: 11, 期号: 3, 页码: 12
作者:
Li, Aoyu
;
Yu, Huahua
;
Li, Rongfeng
;
Liu, Song
;
Xing, Ronge
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/08/28
Nemopilema nomurai nematocyst venom (NnNV)
jellyfish dermatitis
matrix metalloproteinases (MMPs)
inflammatory factors
skin cells
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