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Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 13
作者:  Meng, Xiang-Dong;  Gao, Li-Xin;  Wang, Zhi-Jia;  Feng, Bo;  Zhang, Chun
收藏  |  浏览/下载:30/0  |  提交时间:2021/12/01
Synthesis of 5-Phenyl-1,3,4-thiadiazole Derivatives and Their Biochemical Evaluation against Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase 1 (SHP1) 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3097-3105
作者:  Yu Lijie;  Feng Bo;  Wang Zhijia;  Gao Lixin;  Zhang Chun
收藏  |  浏览/下载:195/0  |  提交时间:2021/11/04
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:  Liu, Wen;  Yin, Ye;  Wang, Meijing;  Fan, Ting;  Zhu, Yuyu
收藏  |  浏览/下载:191/0  |  提交时间:2020/12/24
Phytochemical and biological studies on rare and endangered plants endemic to China. Part XIV. Structurally diverse terpenoids from the twigs and needles of the endangered plant Picea brachytyla 期刊论文
PHYTOCHEMISTRY, 2020, 卷号: 169, 页码: 11
作者:  Jiang, Wei;  Xiong, Juan;  Zang, Yi;  Li, Junmin;  Osman, Ezzat E. A.
收藏  |  浏览/下载:83/0  |  提交时间:2020/07/01
Dietary quercetin potentiates the antiproliferative effect of interferon-alpha in hepatocellular carcinoma cells through activation of JAK/STAT pathway signaling by inhibition of SHP2 phosphatase 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 69, 页码: 113734-113748
作者:  Igbe, I;  Shen, XF;  Jiao, W;  Qiang, Z;  Deng, T
收藏  |  浏览/下载:58/0  |  提交时间:2018/08/28
Quercetin  Interferon  Shp2  Jak  Stat  
Ultra-deep tyrosine phosphoproteomics enabled by a phosphotyrosine superbinder 期刊论文
NATURE CHEMICAL BIOLOGY, 2016, 卷号: 12, 期号: 11, 页码: 959-+
作者:  Liu, Xuguang;  Bian, Yangyang;  Li, Lei;  Dong, Mingming;  Kaneko, Tomonori
收藏  |  浏览/下载:20/0  |  提交时间:2019/06/20
Luteolin sensitizes the antiproliferative effect of interferon alpha/beta by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in cancer cells 期刊论文
CELLULAR SIGNALLING, 2014, 卷号: 26, 期号: 3, 页码: 619-628
Tai, Zhengfu; Lin, Yuan; He, Yujiao; Huang, Junmei; Guo, Jiajia; Yang, Lijuan; Zhang, Guolin; Wang, Fei
收藏  |  浏览/下载:27/0  |  提交时间:2016/01/07
HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice 期刊论文
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 350-362
作者:  Shi, Dayong;  Guo, Shuju;  Jiang, Bo;  Guo, Chao;  Wang, Tao
收藏  |  浏览/下载:28/0  |  提交时间:2014/07/17
HPN, a Synthetic Analogue of Bromophenol from Red Alga Rhodomela confervoides: Synthesis and Anti-Diabetic Effects in C57BL/KsJ-db/db Mice 期刊论文
MARINE DRUGS, 2013, 卷号: 11, 期号: 2, 页码: 350-362
作者:  Shi, Dayong;  Guo, Shuju;  Jiang, Bo;  Guo, Chao;  Wang, Tao
收藏  |  浏览/下载:20/0  |  提交时间:2019/01/08
Suppressor of cytokine signaling 3 inhibits head kidney macrophage activation and cytokine expression in Scophthalmus maximus 期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2011, 卷号: 35, 期号: 2, 页码: 174-181
作者:  Zhang, Min;  Xiao, Zhi-zhong;  Sun, Li
收藏  |  浏览/下载:14/0  |  提交时间:2012/07/03


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