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北京大学 [12]
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5-Aminonaphthalene derivatives as selective nonnucleoside nuclear receptor binding SET domain-protein 2 (NSD2) inhibitors for the treatment of multiple myeloma
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 19
作者:
Wang, Shuni
;
Yang, Hong
;
Su, Mingbo
;
Lian, Fulin
;
Cong, Zhanqing
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2021/11/04
NSD2
Methyltransferase
HTS
Multiple myeloma
5-Aminonaphthalene derivatives
Inhibitor
Synthesis and biological evaluation of novel cabazitaxel analogues
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 41, 页码: 12
作者:
Ren, Sumei
;
Zhang, Minmin
;
Wang, Yujie
;
Guo, Jia
;
Wang, Junfei
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/08/17
Tritium extraction
Hydrogen isotopes
Eutectic Pb-Li
Fusion fuel cycle
Cabazitaxel
Docetaxel
Taxel
Anticancer
Semi-synthesis
10-Deacetylbaccatin III
Cytotoxicity
Transplantation of GMP-grade human iPSC-derived retinal pigment epithelial cells in rodent model: the first pre-clinical study for safety and efficacy in China
期刊论文
ANNALS OF TRANSLATIONAL MEDICINE, 2021, 卷号: 9
作者:
Zhang, Hang
;
Su, Bingnan
;
Jiao, Luyan
;
Xu, Ze-Hua
;
Zhang, Chang-Jun
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/05/31
GMP grade
human iPSCs
RPE cells
pre-clinical study
transplantation
tumorigenicity
Genistein inhibits radiation-induced invasion and migration of glioblastoma cells by blocking the DNA-PKcs/Akt2/Rac1 signaling pathway
期刊论文
RADIOTHERAPY AND ONCOLOGY, 2021, 卷号: 155, 页码: 93-104
作者:
Liu, Xiongxiong
;
Wang, Qiqi
;
Liu, Bingtao
;
Zheng, Xiaogang
;
Li, Ping
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/12/10
Glioblastoma multiforme
DNA-PKcs/Akt2/Rac1 signaling
Genistein
Radiation
Invasion and migration
Design, synthesis and biological evaluation of thioether-containing lenalidomide and pomalidomide derivatives with anti-multiple myeloma activity
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 13
作者:
Wang, Yuhong
;
Mi, Tian
;
Li, Yiming
;
Kan, Weijuan
;
Xu, Gaoya
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Lenalidomide
Multiple myeloma
MM.1S
Late-stage sulfuration
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
Design, synthesis and biological evaluation of the thioether-containing lenalidomide analogs with anti-proliferative activities
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 176, 页码: 419-430
作者:
Xiao, Donghuai
;
Wang, Yu-jie
;
Hu, Xiao-bei
;
Kan, Wei-juan
;
Zhang, Qiumeng
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  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Lenalidomide
Thioether
Anti-Tumor
Structural modification
Comparative Metabonomic Investigations of Schistosoma japonicum From SCID Mice and BALB/c Mice: Clues to Developmental Abnormality of Schistosome in the Immunodeficient Host
期刊论文
FRONTIERS IN MICROBIOLOGY, 2019, 卷号: 10
作者:
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
Schistosoma japonicum
growth and development
SCID mouse
BALB/c mouse
LC-MS/MS
metabolomics
Novel Murine Model of Immune Thrombocytopaenia through Immunized CD41 Knockout Mice
期刊论文
THROMBOSIS AND HAEMOSTASIS, 2019, 卷号: 119, 期号: 3, 页码: 377-383
作者:
Li, Xin
;
Wang, Shu-wen
;
Feng, Qi
;
Hou, Yu
;
Lu, Nan
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/11
bleeding disorder
immune thrombocytopaenia
mouse model
CD41
SCID
mouse
Safety and efficacy of ex vivo expanded CD34(+) stem cells in murine and primate models
期刊论文
2019, 卷号: 10, 期号: 1, 页码: 173
作者:
Zhang, Yu
;
Shen, Bin
;
Guan, Xin
;
Qin, Meng
;
Ren, Zhihua
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/01/03
Long-term HSC
Ex vivo expansion
Human cord blood
Transplantation
NOD
SCID mice
Nonhuman primates
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