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期刊论文 [48]
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PI3K/Akt pathway is involved in the activation of RAW 264.7 cells induced by hydroxypropyltrimethyl ammonium chloride chitosan
期刊论文
JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 卷号: 38, 期号: 3, 页码: 834-840
作者:
Yang Yue
;
Xing Rong'e
;
Liu Song
;
Qin Yukun
;
Li Kecheng
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2020/09/24
hydroxypropyltrimethyl ammonium chloride chitosan
RAW 264
7 cells
PI3K
Akt pathway
nuclear factor-kappa B
activating protein 1
Knockdown of Hypoxia-Inducible Factor 1 alpha (HIF-1 alpha) Promotes Autophagy and Inhibits Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Signaling Pathway in Ovarian Cancer Cells
期刊论文
MEDICAL SCIENCE MONITOR, 2019, 卷号: 25
作者:
Huang, Jinling
;
Gao, Likun
;
Li, Bingshu
;
Liu, Cheng
;
Hong, Shasha
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/12/05
Autophagy
Hypoxia-Inducible Factor 1, alpha Subunit
Ovarian Neoplasms
Phosphatidylinositol 3-Kinases
Signal Transduction
TOR Serine-Threonine Kinases
20-Hydroxy-3-Oxolupan-28-Oic Acid Attenuates Inflammatory Responses by Regulating PI3K-Akt and MAPKs Signaling Pathways in LPS-Stimulated RAW264.7 Macrophages
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 3, 页码: 386
作者:
Cao, Yufeng
;
Li, Fu
;
Luo, Yanyan
;
Zhang, Liang
;
Lu, Shuya
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2021/11/16
inflammation
nitric oxide
macrophage
NF-kappa B
lupane-type triterpene
A phosphatidylinositol 4,5-bisphosphate redistribution-based sensing mechanism initiates a phagocytosis programing
期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9, 页码: 16
作者:
Mu, Libing
;
Tu, Zhongyuan
;
Miao, Lin
;
Ruan, Hefei
;
Kang, Ning
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  |  
浏览/下载:91/0
  |  
提交时间:2018/12/04
Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719
作者:
Zhang, Ning
;
Yu, Zhimei
;
Yang, Xiaohong
;
Zhou, Yan
;
Wang, Jia
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2019/01/08
Anticancer drug
Phosphatidylinositol 3-kinase
Structure-activity relationship
Serum and glucocorticoid inducible protein kinases (SGKs): a potential target for cancer intervention
期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 5, 页码: 767-771
作者:
Basnet, Rajesh
;
Gong, Grace Qun
;
Li, Chenyao
;
Wang, Ming-Wei
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  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
SGK
AKT
PI3K
Cancer
Signalling: Kinase
Inhibitor
Collapsin Response Mediator Protein-2 Ameliorates Sevoflurane-Mediated Neurocyte Injury by Targeting PI3K-mTOR-S6K Pathway
期刊论文
MEDICAL SCIENCE MONITOR, 2018, 卷号: 24, 页码: 4982-4991
作者:
He, Jiaxuan
;
Zhu, Jianfang
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/11/19
Neurocysticercosis
Phosphatidylinositol 3-Kinases
TOR Serine-Threonine Kinases
Polysaccharide FMP-1 from Morchella esculenta attenuates cellular oxidative damage in human alveolar epithelial A549 cells through PI3K/AKT/Nrf2/HO-1 pathway.
期刊论文
International Journal of Biological Macromolecules, 2018, 卷号: Vol.120 Part A, 页码: 865-875
作者:
Zhang, Wen-Na
;
Cai, Zheng-Nan
;
Li, Wan
;
Chen, Yan
;
Pan, Wen-Juan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/04/24
POLYSACCHARIDES
*MORELS
*OXIDATIVE
stress
*EPITHELIAL
cells
*PHOSPHATIDYLINOSITOL
kinases
Mangiferin Potentiates Neuroprotection by Isoflurane in Neonatal Hypoxic Brain Injury by Reducing Oxidative Stress and Activation of Phosphatidylinositol-3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling
期刊论文
MEDICAL SCIENCE MONITOR, 2018, 卷号: 24, 页码: 7459-7468
作者:
Xi, Jia-shui
;
Wang, Yu-fen
;
Long, Xin-xin
;
Ma, Yan
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/12/11
Brain Injuries
Cell Hypoxia
Isoflurane
Phosphatidylinositol 3-Kinases
Anti-neuroinflammatory effects of 20C from Gastrodia elata via regulating autophagy in LPS-activated BV-2 cells through MAPKs and TLR4/Akt/mTOR signaling pathways
期刊论文
Molecular Immunology, 2018, 卷号: 99, 页码: 115-123
作者:
Shao, Qian-hang
;
Zhang, Xiao-ling
;
Chen, Ying
;
Zhu, Cheng-Gen
;
Shi, Jian-Gong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/12/27
Akt
protein kinase B
Atg
autophagy related gene
CNS
central nervous system
COX-2
cyclooxygenase-2
CQ
chloroquine
ERK
extracellular signal-regulated kinase
IL-1β
interleukin-1β
iNOS
inducible nitric oxide synthase
JNK
c-jun NH2-terminal kinase
LPS
Lipopolysaccharide
MAPKs
mitogen-activated protein kinases
mTOR
mechanistic target of rapamycin
NO
nitric oxide
PI3K
phosphatidylinositol 3-kinase
PRR
pattern recognition receptor
TLR4
toll like receptor 4
TNF-α
tumor necrosis factor-α
20C
Autophagy
Mitogen-activated protein kinases (MAPKs)
Toll like receptor 4 (TLR4)
Protein kinase B (Akt)
Mechanistic target of rapamycin (mTOR)
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