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Intestinal farnesoid X receptor signaling controls hepatic fatty acid oxidation 期刊论文
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2022, 卷号: 1867, 期号: 2, 页码: 13
作者:  Lu, Dasheng;  Liu, Yameng;  Luo, Yuhong;  Zhao, Jie;  Feng, Chao
收藏  |  浏览/下载:49/0  |  提交时间:2022/01/18
Discovery of a Potential Liver Fibrosis Inhibitor from a Mushroom Endophytic Fungus by Genome Mining of a Silent Biosynthetic Gene Cluster 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 38, 页码: 11303-11310
作者:  Cheng, Jin-Tao;  Wang, Han-Min;  Yu, Jia-Hui;  Sun, Chen-Fan;  Cao, Fei
收藏  |  浏览/下载:28/0  |  提交时间:2021/12/01
Discovery of novel ketoxime ether derivatives with potent FXR agonistic activity, oral effectiveness and high liver/blood ratio 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 43, 页码: 13
作者:  Tang, Xuehang;  Ning, Mengmeng;  Ye, Yangliang;  Gu, Yipei;  Yan, Hongyi
收藏  |  浏览/下载:49/0  |  提交时间:2021/11/04
A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage 期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2021, 卷号: 120, 页码: 12
作者:  Huang, Suling;  Wu, Yanwei;  Zhao, Zhuohui;  Wu, Bing;  Sun, Kai
收藏  |  浏览/下载:89/0  |  提交时间:2021/08/17
Discovery and Optimization of Non-bile Acid FXR Agonists as Preclinical Candidates for the Treatment of Nonalcoholic Steatohepatitis 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 21, 页码: 12748-12772
作者:  Li, Junyou;  Liu, Mengqi;  Li, Yazhou;  Sun, Dan-dan;  Shu, Zhihao
收藏  |  浏览/下载:22/0  |  提交时间:2021/05/24
A novel bile acid analog, A17, ameliorated non-alcoholic steatohepatitis in high-fat diet-fed hamsters 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 卷号: 404, 页码: 14
作者:  Wang, Ying;  Zhu, Yao;  Niu, Junxing;  Deng, Qiangqiang;  Guo, Shimeng
收藏  |  浏览/下载:60/0  |  提交时间:2020/12/21
The protective effect and mechanism of the FXR agonist obeticholic acid via targeting gut microbiota in non-alcoholic fatty liver disease 期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13
作者:  Zhang, Dan-Ying;  Zhu, Lin;  Liu, Hai-Ning;  Tseng, Yu-Jen;  Weng, Shu-Qiang
收藏  |  浏览/下载:25/0  |  提交时间:2019/12/05
FXR-Dependent Modulation of the Human Small Intestinal Microbiome by the Bile Acid Derivative Obeticholic Acid 期刊论文
Gastroenterology, 2018, 卷号: Vol.155 No.6, 页码: 1741-1752(e5)
作者:  Elliot S. Friedman;  Yun Li;  Ting-Chin David Shen;  Jack Jiang;  Lillian Chau
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/26
Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer 期刊论文
Gastroenterology, 2018, 卷号: 155, 期号: 2, 页码: 557-571.e14
作者:  Liu, Ting;  Yang, Heping;  Fan, Wei;  Tu, Jian;  Li, Tony W. H.
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/27
Chemoproteomic Profiling of Bile Acid Interacting Proteins 期刊论文
ACS CENTRAL SCIENCE, 2017
Zhuang, Shentian; Li, Qiang; Cai, Lirong; Wang, Chu; Lei, Xiaoguang
收藏  |  浏览/下载:10/0  |  提交时间:2017/12/03


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