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Enhanced Anti-diabetic Effect of Berberine Combined With Timosaponin B2 in Goto-Kakizaki Rats, Associated With Increased Variety and Exposure of Effective Substances Through Intestinal Absorption 期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 15
作者:  Tian, Xiaoting;  Liu, Fang;  Li, Zhixiong;  Lin, Yunfei;  Liu, Huan
收藏  |  浏览/下载:18/0  |  提交时间:2020/07/01
Dual actions of norathyriol as a new candidate hypouricaemic agent: uricosuric effects and xanthine oxidase inhibition 期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2019, 卷号: 853
作者:  Lin, Hua;  Tu, Caixia;  Niu, Yanfen;  Li, Fashuang;  Yuan, Lixian
收藏  |  浏览/下载:21/0  |  提交时间:2019/12/04
Discovery of potent PTP1B inhibitors via structure-based drug design, synthesis and in vitro bioassay of Norathyriol derivatives 期刊论文
2019, 卷号: 86, 页码: 224-234
作者:  Xue, Wenjie;  Tian, Jinlong;  Wang, Xiang Simon;  Xia, Jie;  Wu, Song
收藏  |  浏览/下载:11/0  |  提交时间:2020/01/03
Metabolism, pharmacokinetics, and hepatic disposition of xanthones and saponins on Zhimu treatments for exploratively interpreting the discrepancy between the herbal safety and timosaponin A3-induced hepatotoxicity 期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1923-1934
作者:  Xie, Yang;  Zhou, Xu;  Pei, Hu;  Chen, Ming-Cang;  Sun, Zhao-Lin
收藏  |  浏览/下载:93/0  |  提交时间:2019/01/08
Absorption, Metabolism, and Pharmacokinetics Profiles of Norathyriol, an Aglycone of Mangiferin, in Rats by HPLC-MS/MS 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018, 卷号: 66, 期号: 46, 页码: 12227-12235
作者:  Guo, Xiaozhen;  Cheng, Mingcang;  Hu, Pei;  Shi, Zhangpeng;  Chen, Shuoji
收藏  |  浏览/下载:266/0  |  提交时间:2019/01/08
metabolismpharmacokineticsandhepaticdispositionofxanthonesandsaponinsonzhimutreatmentsforexplorativelyinterpretingthediscrepancybetweentheherbalsafetyandtimosaponina3inducedhepatotoxicity 期刊论文
actapharmacologicasinica, 2018, 卷号: 39, 期号: 12, 页码: 1923
作者:  Xie Yang;  Zhou Xu;  Pei Hu;  Chen Mingcang;  Sun Zhaolin
收藏  |  浏览/下载:5/0  |  提交时间:2020/07/01
Hypouricaemic action of mangiferin results from metabolite norathyriol via inhibiting xanthine oxidase activity 期刊论文
PHARMACEUTICAL BIOLOGY, 2016, 卷号: 54, 期号: 9, 页码: 1680-1686
作者:  Niu, Yanfen;  Liu, Jia;  Liu, Hai-Yang;  Gao, Li-Hui;  Feng, Guo-Hua
收藏  |  浏览/下载:25/0  |  提交时间:2017/01/05
Pharmacokinetics of mangiferin and its metabolite-Norathyriol, Part 1: Systemic evaluation of hepatic first-pass effect in vitro and in vivo 期刊论文
BIOFACTORS, 2016, 卷号: 42, 期号: 5, 页码: 533-544
作者:  Tian, Xiaoting;  Gao, Yu;  Xu, Zhou;  Lian, Shan;  Ma, Yuanjie
收藏  |  浏览/下载:24/0  |  提交时间:2019/01/08
Pharmacokinetics of mangiferin and its metabolite-Norathyriol, Part 2: Influence of UGT, CYP450, P-gp, and enterobacteria and the potential interaction in Rhizoma Anemarrhenae decoction with timosaponin B2 as the major contributor 期刊论文
BIOFACTORS, 2016, 卷号: 42, 期号: 5, 页码: 545-555
作者:  Tian, Xiaoting;  Xu, Zhou;  Li, Zhixiong;  Ma, Yuanjie;  Lian, Shan
收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08
Hypouricaemic action of mangiferin results from metabolite norathyriol via inhibiting xanthine oxidase activity 期刊论文
PHARMACEUTICAL BIOLOGY, 2016, 卷号: 54, 期号: 9
作者:  Li, Ling;  Niu, Yanfen;  Liu, Jia;  Liu, Hai-Yang;  Gao, Li-Hui
收藏  |  浏览/下载:7/0  |  提交时间:2019/12/04


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