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CORC

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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:  Liu, Yingqiang;  Lai, Mengzhen
收藏  |  浏览/下载：62/0  |  提交时间：2022/01/18
Oxidized Low-Density Lipoprotein Links Hypercholesterolemia and Bladder Cancer Aggressiveness by Promoting Cancer Stemness 期刊论文
CANCER RESEARCH, 2021, 卷号: 81, 期号: 22, 页码: 5720-5732
作者:  Yang, Lin;  Sun, Jingya;  Li, Meiqian;  Long, Yiming;  Zhang, Dianzheng
收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04
A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies 期刊论文
MOLECULAR CELL, 2021, 卷号: 81, 期号: 19, 页码: 4076-+
作者:  Liu, Zhiwei;  Liu, Yingluo;  Qian, Lili;  Jiang, Shangwen;  Gai, Xiameng
收藏  |  浏览/下载：27/0  |  提交时间：2021/12/01
Insights into agonist-elicited activation of the human glucose-dependent insulinotropic polypeptide receptor 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 192, 页码: 16
作者:  Yuliantie, Elita;  van der Velden, Wijnand J. C.;  Labroska, Viktorija;  Dai, Antao;  Zhao, Fenghui
收藏  |  浏览/下载：44/0  |  提交时间：2021/11/04
Discovery of a Potential Liver Fibrosis Inhibitor from a Mushroom Endophytic Fungus by Genome Mining of a Silent Biosynthetic Gene Cluster 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 38, 页码: 11303-11310
作者:  Cheng, Jin-Tao;  Wang, Han-Min;  Yu, Jia-Hui;  Sun, Chen-Fan;  Cao, Fei
收藏  |  浏览/下载：28/0  |  提交时间：2021/12/01
Global identification of phospho-dependent SCF substrates reveals a FBXO22 phosphodegron and an ERK-FBXO22-BAG3 axis in tumorigenesis 期刊论文
CELL DEATH AND DIFFERENTIATION, 2021, 页码: 13
作者:  Liu, Ping;  Cong, Xiaoji;  Liao, Shengjie;  Jia, Xinglong;  Wang, Xiaomin
收藏  |  浏览/下载：79/0  |  提交时间：2021/08/17
Design, synthesis and pharmacological evaluation of bicyclic and tetracyclic pyridopyrimidinone analogues as new KRAS(G12C) inhibitors 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 213, 页码: 17
作者:  Xiao, Xuanzheng;  Lai, Mengzhen;  Song, Zilan;  Geng, Meiyu;  Ding, Jian
收藏  |  浏览/下载：47/0  |  提交时间：2021/05/24
Design, Synthesis, and Biological Evaluation of IRAK4-Targeting PROTACs 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 1, 页码: 82-87
作者:  Chen, Yun;  Ning, Yi;  Bai, Gang;  Tong, Linjiang;  Zhang, Tao
收藏  |  浏览/下载：19/0  |  提交时间：2021/05/24
SAF-189s, a potent new-generation ROS1 inhibitor, is active against crizotinib-resistant ROS1 mutant-driven tumors 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 7
作者:  Xia, Zong-jun;  Ji, Yin-chun;  Sun, De-qiao;  Peng, Xia;  Gao, Ying-lei
收藏  |  浏览/下载：76/0  |  提交时间：2020/12/21
Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 16, 页码: 6
作者:  Su, Zhicheng;  Yang, Tingyuan;  Wang, Jie;  Lai, Mengzhen;  Tong, Linjiang
收藏  |  浏览/下载：27/0  |  提交时间：2020/12/24
EGFR  NSCLC  C797S  

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